Practice “Safe Stress!”

DCIM100GOPROLet’s face it, life is becoming increasingly busy with work, family, social media, and things that go beep all around us. All this stimulation sets off our internal alarm buttons, and gives our physical bodies unnecessary alerts. The messages we receive tell us that it’s hard to stay afloat of all the events and time commitments around us.   It can make you  feel like you are drowning in paper work, or going under with financial burdens. Many feel overwhelmed with commitments or unfinished projects.

STRESS!  Stress!  Stress!

It’s a killer. It’s the NUMBER ONE cause of all illnesses!  I must admit that I didn’t believe it until I felt the effects. Its A sneaky– under the radar– black cloud that just niggles at your adrenal glands until you have nothing more to put out, and find yourself struggling to get out of bed in the morning, or tossing and turning unable to fall asleep at night —Stress_2without popping a pill.  Curiously most of us just don’t recognise that we have this monkey on our back, until we actually do fall apart with some physical signs, such as autoimmune diseases, diabetes, hypertension, rheumatoid arthritis, allergic skin disorders, back aches, disc diseases, Digestive problems,  Cancer (through lowering your immune vigilance) heart palpitations and fibrillation or Thyroid conditions.

Image by Gdudycha :  The effects of stress on the body.

Stress from too much emotional, physical, or mental stimulation needs to be calmed. Stress causes your adrenals to push out the hormones of adrenaline, noradrenaline and cortisol. This can lead to inflammation and wear and tear on your body, it also pushes up your blood sugar and insulin levels, leading to that middle belly fat store and liver diseases.

Some stress is ok, but when we continually burn our adrenals and force them to pump out stress hormones, our bodies go to ground. PTSD or post traumatic stress disorder is a longer term effect.

Nurture and nourish your body and soul. You are here for the long haul, not just for a couple of exams or a University course, a stressful job, parenting a child with autism, or a difficult marriage, or a speeding ticket.  There options and ways to handle your stress levels, even if you cannot completely control your environment/relationship/job.

Here are  top 7 stress busters:

  1. Organize- Clutter control is the key to staying organized. Keep a wastebasket close by and throw away things that you no longer need. Dedicate at least 15 minutes of your time to organizing your study area so you do not have to waste time sorting through rubbles of books and papers when looking for something. Remove and give away excess clothing, pottery, kitchen ware, magazines, newspapers.
  2. Learn how to say “No”- Don’t get over-involved. You don’t have to join every activity, every club, and every community project. You do not have to accept all invitations to socialize with friends. Evaluate your schedule and check your to-do list to see what tasks are important and accomplish them first.
  3. Exercise- Regular exercise releases muscle tension and will rev up your energy. Join a yoga class, Qi Gong, Tai Chi, Swim, go for a walk with a friend, or get up and dance in your living room. You don’t need fancy exercise machines to get regular exercise. Any type of exercise is good for your body and mind. Take a break daily to smell the grass, roses and exercise at the same time. DSC_0720
  4. Eat nutritiously- Students, nurses, doctors and busy housewives, executives and police officers are notorious for not eating right. A healthy diet can enhance your body and mental functions. A poor diet can zap you of brainpower. So grab a fruit, a veggie plate, or nutrition bar when you are hungry or have no time to prepare a healthy meal.
  5. Get enough sleep- Students, shift workers, and Medical professionals  are among the most sleep-deprived group of people due to over-commitment. Getting enough sleep will rebuild your energy and will make you feel better.
  6. Herbal Helpers- The gardening principle comes into play when nourishing your body- to last a lifetime, you will need to spend a lifetime looking after your adrenals, “weed out” the stress by removing yourself from stressful situations, and feed them well replenish them with some of the following herbs at periods of stress with these adaptogens: Withania somnifera= Ashwaganda, Rehmannia glutinosa, Rhodiola, American Ginseng (Panax quinquefolius), Astragalus membranaceus, Bacopa monnieri, Eleutherococcus senticosus (Siberian Ginseng).  See a Naturopath for a consultation to tweak your own personal herbal formula.
  7. Essential oils- Good quality oils and aromatherapy massages can help your brain and adrenals recover. The oils must be of a therapeutic non contaminated blend and individualised for the person’s requirements, preferably by seeing a qualified aromatherapist. Some useful blends might include some of the following: Bergamot, Patchouli, Blood Orange, Ylang Ylang, Chamomile, Jasmine, Lavender, Rose, Sandlewood, and Grapefruit essential oils.

And lastly, remember to SMILE!    Life is a present. Open yourself to receiving JOY.

Hug your dog, neighbour’s dog, friends dog…..or get a nice well behaved and friendly dog- they make you smile!

DSC_0561smile pup

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Vaccinology: for those that need to see the science

….here are 332 studies which show the other side of the issue.
To believe vaccination is 100 effective and that it does not have any major side effects is an absolute contortion of the scientific facts. To make vaccination mandatory takes away our freedom of choice and makes a mockery of informed consent. There is a humans rights issue involved here too with regards to mandatory vaccination.” – scroll down to see the studies:
Link Between Neurologic and Immune Disorders
Aluminum
Aluminum Vaccine Adjuvants: Are they Safe?
http://www.ncbi.nlm.nih.gov/pubmed/21568886
Mechanisms of aluminum adjuvant toxicity and autoimmunity in pediatric populations
http://lup.sagepub.com/content/21/2/223.short
Aluminum hydroxide injections lead to motor deficits and motor neuron degeneration
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819810/
Long-term Persistence of Vaccine-Derived Aluminum Hydroxide is Associated with Chronic Cognitive Dysfunction
http://www.sciencedirect.com/…/article/pii/S0162013409001895
Long-term follow-up of cognitive dysfunction in patients with aluminum hydroxide-induced macrophagic myofasciitis (MMF).
http://www.sciencedirect.com/…/article/pii/S0162013411002194
Do aluminum vaccine adjuvants contribute to the rising prevalence of autism?
http://www.ncbi.nlm.nih.gov/pubmed/22099159
Aluminum Adjuvant Linked to Gulf War Illness Induces Motor Neuron Death in Mice
http://www.springerlink.com/content/x457214811q62412/
The immunobiology of aluminium adjuvants: how do they really work?
http://www.sciencedirect.com/…/article/pii/S1471490609002488
Aluminum inclusion macrophagic myofasciitis: a recently identified condition
http://www.ncbi.nlm.nih.gov/pubmed/14753387
Macrophagic myofasciitis lesions assess long-term persistence of vaccine-derived aluminium hydroxide in muscle
http://brain.oxfordjournals.org/content/…/1821.full.pdf+html
A role for the body burden of aluminium in vaccine-associated macrophagic myofasciitis and chronic fatigue syndrome
http://www.medical-hypotheses.com/…/S0306-9877(08)…/abstract
Aluminum as an adjuvant in Crohn’s disease induction
http://lup.sagepub.com/content/21/2/231.abstract
Aluminum is a potential environmental factor for Crohn’s disease induction: extended hypothesis
http://www.ncbi.nlm.nih.gov/pubmed/17804561
DNA released from dying host cells mediates aluminum adjuvant activity
http://www.nature.com/nm/journal/v17/n8/full/nm.2403.html
Mercury
Sorting out the spinning of autism: heavy metals and the question of incidence
This file is a PDF http://www.ane.pl/pdf/7021.pdf
Comparison of blood and brain mercury levels in infant monkeys exposed to methylmercury or vaccines containing thimerosal
http://www.ncbi.nlm.nih.gov/pubmed/16079072
A Case Series of Children with Apparent Mercury Toxic Encephalopathies Manifesting with Clinical Symptoms of Regressive Autistic Disorders
http://www.ncbi.nlm.nih.gov/pubmed/17454560
Neurodevelopmental disorders following thimerosal-containing childhood immunizations: a follow-up analysis
http://www.ncbi.nlm.nih.gov/pubmed/15764492
Persistent behavioral impairments and alterations of brain dopamine system after early postnatal administration of thimerosal in rats
http://www.ncbi.nlm.nih.gov/pubmed/21549155
Maternal thimerosal exposure results in aberrant cerebellar oxidative stress, thyroid hormone metabolism, and motor behavior in rat pups; sex- and strain-dependent effects
http://www.ncbi.nlm.nih.gov/pubmed/22015705
Neonatal administration of thimerosal causes persistent changes in mu opioid receptors in the rat brain
http://www.ncbi.nlm.nih.gov/pubmed/20803069
Integrating experimental (in vitro and in vivo) neurotoxicity studies of low-dose thimerosal relevant to vaccines
http://www.ncbi.nlm.nih.gov/pubmed/21350943
Thimerosal-Derived Ethylmercury Is a Mitochondrial Toxin in Human Astrocytes: Possible Role of Fenton Chemistry in the Oxidation and Breakage of mtDNA
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395253/
Activation of methionine synthase by insulin-like growth factor-1 and dopamine: a target for neurodevelopmental toxins and thimerosal
http://www.ncbi.nlm.nih.gov/pubmed/14745455
Administration of thimerosal to infant rats increases overflow of glutamate and aspartate in the prefrontal cortex: protective role of dehydroepiandrosterone sulfate.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264864/
Neurologic and Immune Development
The Emerging Link Between Autoimmune Disorders and Neuropsychiatric Disease
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086677/
Influence of pediatric vaccines on amygdala growth and opioid ligand binding in rhesus macaque infants: A pilot study
This file is a PDF http://www.ane.pl/pdf/7020.pdf
Primary Immunization of Premature Infants with Gestational Age <35 Weeks: Cardiorespiratory Complications and C-Reactive Protein Responses Associated with Administration of Single and Multiple Separate Vaccines Simultaneously
http://www.jpeds.com/article/S0022-3476(07)00185-0/abstract
Neonatal administration of thimerosal causes persistent changes in mu opioid receptors in the rat brain
http://www.ncbi.nlm.nih.gov/pubmed/20803069
Maternal thimerosal exposure results in aberrant cerebellar oxidative stress, thyroid hormone metabolism, and motor behavior in rat pups; sex- and strain-dependent effects
http://www.ncbi.nlm.nih.gov/pubmed/22015705
Administration of thimerosal to infant rats increases overflow of glutamate and aspartate in the prefrontal cortex: protective role of dehydroepiandrosterone sulfate.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264864/
Molecular mechanisms underlying anti-inflammatory phenotype of neonatal splenic macrophages
http://www.jleukbio.org/content/82/2/403.full.pdf+html
Abnormal measles-mumps-rubella antibodies and CNS autoimmunity in children with autism
http://www.ncbi.nlm.nih.gov/pubmed/12145534
Integrating experimental (in vitro and in vivo) neurotoxicity studies of low-dose thimerosal relevant to vaccines
http://www.ncbi.nlm.nih.gov/pubmed/21350943
Serological association of measles virus and human herpesvirus-6 with brain autoantibodies in autism
http://www.ncbi.nlm.nih.gov/pubmed/9756729
In Harm’s Way: Toxic Threats to Child Development
http://action.psr.org/site/DocServer/frontmatter.pdf
Novel roles for immune molecules in neural development: implications for neurodevelopmental disorders (Many toxic insults discussed but not vaccines.)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059681/
Immune Activation in Brain Aging and Neurodegeneration: Too Much or Too Little?
http://www.sciencedirect.com/…/article/pii/S0896627309006771
Neurologic and Immune Dysfunction
Primary Immunization of Premature Infants with Gestational Age <35 Weeks: Cardiorespiratory Complications and C-Reactive Protein Responses Associated with Administration of Single and Multiple Separate Vaccines Simultaneously
http://www.jpeds.com/article/S0022-3476(07)00185-0/abstract
Neurodevelopmental disorders following thimerosal-containing childhood immunizations: a follow-up analysis
http://www.ncbi.nlm.nih.gov/pubmed/15764492
Persistent behavioral impairments and alterations of brain dopamine system after early postnatal administration of thimerosal in rats
http://www.ncbi.nlm.nih.gov/pubmed/21549155
Maternal thimerosal exposure results in aberrant cerebellar oxidative stress, thyroid hormone metabolism, and motor behavior in rat pups; sex- and strain-dependent effects
http://www.ncbi.nlm.nih.gov/pubmed/22015705
Administration of thimerosal to infant rats increases overflow of glutamate and aspartate in the prefrontal cortex: protective role of dehydroepiandrosterone sulfate
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264864/
A possible central mechanism in autism spectrum disorders, part 1
http://www.ncbi.nlm.nih.gov/pubmed/19043938
A possible central mechanism in autism spectrum disorders, part 2: immunoexcitotoxicity
http://www.ncbi.nlm.nih.gov/pubmed/19161050
A possible central mechanism in autism spectrum disorders, part 3: the role of excitotoxin food additives and the synergistic effects of other environmental toxins
http://www.ncbi.nlm.nih.gov/pubmed/19284184
Oily adjuvants and autoimmunity: now time for reconsideration?
http://lup.sagepub.com/content/21/2/217.abstract
Evidence of Mitochondrial Dysfunction in Autism and Implications for Treatment
This file is a PDF http://www.icdrc.org/documents/Mitoandautism2008.pdf
Fatal outcome after postexposure rabies vaccination in a patient with Parkinson’s disease
http://www.ncbi.nlm.nih.gov/pubmed/15675624
Specific Vaccines
Neurological Complications of Pertussis Immunization
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025848/?page=1
DPT Vaccine and Chronic Nervous System Dysfunction: A New Analysis
http://www.nap.edu/catalog.php?record_id=9814#toc
Abnormal measles-mumps-rubella antibodies and CNS autoimmunity in children with autism
http://www.ncbi.nlm.nih.gov/pubmed/12145534
Pertussis toxin is required for pertussis vaccine encephalopathy
This file is a PDF http://www.ncbi.nlm.nih.gov/…/PMC391…/pdf/pnas00364-0469.pdf
Hepatitis B triple series vaccine and developmental disability in US children aged 1-9 years
http://www.tandfonline.com/doi/abs/10.1080/02772240701806501
CNS demyelination and quadrivalent HPV vaccination
http://msj.sagepub.com/content/15/1/116.short
Increased Incidence and Clinical Picture of Childhood Narcolepsy following the 2009 H1N1 Pandemic Vaccination Campaign in Finland
http://www.plosone.org/…/info%3Adoi%2F10.1371%2Fjournal.pon…
Safety and immunogenicity of H5N1 vaccine
http://www.thelancet.com/…/PIIS0140-6736(06)69891-7/fulltext
Child influenza vaccination: Ramifications of adverse events in children in Australia
http://www.bmj.com/content/340/bmj.c2994
Progression of Renal Disease in Henoch-Schönlein Purpura After Influenza Vaccination
(Click PDF in upper right corner for full text)
http://jama.jamanetwork.com/article.aspx?articleid=367705
Henoch–Schönlein purpura following meningitis C vaccination
http://rheumatology.oxfordjournals.org/content/40/3/345.full
Fatal outcome after postexposure rabies vaccination in a patient with Parkinson’s disease
http://www.ncbi.nlm.nih.gov/pubmed/15675624
Brain Inflammation (encephalitis) Post Vaccination
Neurological Complications of Pertussis Immunization
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025848/?page=1
Acute disseminated encephalomyelitis
http://www.neurology.org/content/68/16_suppl_2/S23.abstract
Acute disseminated encephalomyelitis following influenza vaccination
Full text available by clicking PDF in upper right corner
http://archneur.jamanetwork.com/article.aspx
A Case Series of Children with Apparent Mercury Toxic Encephalopathies Manifesting with Clinical Symptoms of Regressive Autistic Disorders
http://www.ncbi.nlm.nih.gov/pubmed/17454560
Vaccination against Whooping-Cough: Efficacy versus Risks
http://www.sciencedirect.com/…/article/pii/S0140673677910285
DPT Vaccine and Chronic Nervous System Dysfunction: A New Analysis
http://www.nap.edu/catalog.php?record_id=9814#toc
Acute disseminated encephalomyelitis
http://pmj.bmj.com/content/79/927/11.full
Pertussis toxin is required for pertussis vaccine encephalopathy
This file is a PDF http://www.ncbi.nlm.nih.gov/…/PMC391…/pdf/pnas00364-0469.pdf
Acute necrotizing encephalopathy secondary to diphtheria, tetanus toxoid and whole-cell pertussis vaccination: diffusion-weighted imaging and proton MR spectroscopy findings
http://www.springerlink.com/content/44xt417387hx4877/
The smallpox vaccine and postvaccinal encephalitis
http://www.ncbi.nlm.nih.gov/pubmed/12170398
Encephalo-Myelitis following Vaccination
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2047920/
Encephalo-Myelitis following Vaccination
http://actx.beta.download.thelancet.com/…/PIIS0140…/fulltext
Subacute sclerosing panencephalitis–the continuing threat
Deaths Attributable to Smallpox Vaccination, 1959 to 1966, and 1968
Click PDF in upper right corner for full text.
http://jama.jamanetwork.com/article.aspx
Acute encephalopathy and chronic neurological damage after pertussis vaccine
http://www.ncbi.nlm.nih.gov/pubmed/7906066
Encephalopathies following prophylactic pertussis vaccine
http://pediatrics.aappublications.org/content/…/437.abstract
Treatment of lethal pertussis vaccine reaction with histamine H1 antagonists
http://www.neurology.org/content/37/6/1068
Murine model for pertussis vaccine encephalopathy: linkage to H-2
http://www.nature.com/…/journal/v299/n5885/abs/299738a0.html
Autoimmune Disease
‘ASIA’ – Autoimmune/Inflammatory Syndrome
‘ASIA’ – Autoimmune/Inflammatory Syndrome Induced by Adjuvants
http://www.ncbi.nlm.nih.gov/pubmed/20708902
The spectrum of ASIA: ‘Autoimmune (Auto-inflammatory) Syndrome induced by Adjuvants’
http://lup.sagepub.com/content/21/2/118.full.pdf+html
ASIA: A New Way to Put the Puzzle Together: Autoimmune (autoinflammatory) syndrome induced by adjuvants provides a diagnostic framework for enigmatic conditions
http://www.the-rheumatologist.org/…/ASIA_A_New_Way_to_Put_t…
Induction of the ‘ASIA’ syndrome in NZB/NZWF1 mice after injection of complete Freund’s adjuvant (CFA)
http://lup.sagepub.com/content/21/2/203.abstract
The common immunogenic etiology of chronic fatigue syndrome: from infections to vaccines via adjuvants to the ASIA syndrome
http://www.ncbi.nlm.nih.gov/pubmed/22054760
Shoenfeld’s Syndrome After Pandemic Influenza A/H1N1 Vaccination (Download free full text by clicking ACTA Reumatologica Portuguesa in upper right corner.)
http://www.ncbi.nlm.nih.gov/pubmed/21483283
Human Adjuvant Disease Induced by Foreign Substances: A New Model of ASIA
http://lup.sagepub.com/content/21/2/128.full.pdf+html
Gulf War Syndrome as a part of the autoimmune (autoinflammatory) syndrome induced by adjuvant (ASIA)
http://lup.sagepub.com/content/21/2/190.abstract
Adjuvant Immunization Induces High Levels of Pathogenic Antiphospholipid Antibodies in Genetically Prone Mice: Another Facet of the ASIA Syndrome
http://lup.sagepub.com/content/21/2/210.abstract
Autoimmunity Following Hepatitis B Vaccine as Part of the Spectrum of ‘Autoimmune (Auto-inflammatory) Syndrome Induced by Adjuvants’ (ASIA): analysis of 93 cases
http://lup.sagepub.com/content/21/2/146.abstract
Macrophagic Myofasciitis
Macrophagic myofasciitis lesions assess long-term persistence of vaccine-derived aluminium hydroxide in muscle
http://brain.oxfordjournals.org/content/…/1821.full.pdf+html
Macrophagic myofasciitis: characterization and pathophysiology
http://lup.sagepub.com/content/21/2/184.abstract
Lessons From Macrophagic Myofasciitis: Towards Definition of a Vaccine Adjuvant-Related Syndrome
http://www.ncbi.nlm.nih.gov/pubmed/12660567
AlOH3-adjuvanted vaccine-induced macrophagic myofasciitis in rats is influenced by the genetic background
http://www.ncbi.nlm.nih.gov/pubmed/16616846
Multiple Sclerosis and Demyelinating Disease
Recombinant Hepatitis B Vaccine and the Risk of Multiple Sclerosis: a Prospective Study
http://www.ncbi.nlm.nih.gov/pubmed/15365133
CNS Demyelination and Quadrivalent HPV Vaccination
http://msj.sagepub.com/content/15/1/116.short
Asthma and Allergy
Is infant immunization a risk factor for childhood asthma or allergy?
http://www.ncbi.nlm.nih.gov/pubmed/9345669
Infection of Human B Lymphocytes with MMR Vaccine Induces IgE Class Switching
http://www.ncbi.nlm.nih.gov/pubmed/11513549
Delay in diphtheria, pertussis, tetanus vaccination is associated with a reduced risk of childhood asthma
http://www.jacionline.org/ar…/S0091-6749(07)02379-2/fulltext
Effects of diphtheria-tetanus-pertussis or tetanus vaccination on allergies and allergy-related respiratory symptoms among children and adolescents in the United States
http://www.ncbi.nlm.nih.gov/pubmed/10714532
Vaccination and Allergic Disease: A Birth Cohort Study
(Interesting to note that the data show a risk of allergic disease after vaccination but the authors dismiss it in their conclusion.)
http://ajph.aphapublications.org/…/pdf/10.2105/AJPH.94.6.985
The relationship between vaccine refusal and self-report of atopic disease in children
http://www.sciencedirect.com/…/article/pii/S0091674905000266
Rheumatic Disease
Immunization of patients with autoimmune inflammatory rheumatic diseases (the EULAR recommendations)
http://lup.sagepub.com/content/21/2/162.abstract
Chronic Arthritis after Rubella Vaccination
http://cid.oxfordjournals.org/content/15/2/307.short
Autoimmune response following influenza vaccination in patients with autoimmune inflammatory rheumatic disease
http://lup.sagepub.com/content/21/2/175.abstract
Giant cell arteritis and polymyalgia rheumatica after influenza vaccination: report of 10 cases and review of the literature
http://lup.sagepub.com/content/21/2/153.abstract
Diabetes
Pertussis infections, vaccines and Type 1 diabetes
http://onlinelibrary.wiley.com/…/j.1464-5491.2004.0114…/full
Clustering of cases of type 1 diabetes mellitus occurring 2-4 years after vaccination is consistent with clustering after infections and progression to type 1 diabetes mellitus in autoantibody positive individuals
http://www.ncbi.nlm.nih.gov/pubmed/12793601
Clustering of cases of insulin dependent diabetes (IDDM) occurring three years after hemophilus influenza B (HiB) immunization support causal relationship between immunization and IDDM
http://www.ncbi.nlm.nih.gov/pubmed/12482192
Vaccines and the risk of insulin-dependent diabetes (IDDM): potential mechanism of action
http://www.medical-hypotheses.com/…/S0306-9877(01)…/abstract
Italian pediatric data support hypothesis that simultaneous epidemics of type 1 diabetes and type 2 diabetes/metabolic syndrome/obesity are polar opposite responses (i.e., symptoms) to a primary inflammatory condition
http://www.degruyter.com/…/…/jpem.2011.023/jpem.2011.023.xml
Specific Vaccines and Autoimmunity
Abnormal measles-mumps-rubella antibodies and CNS autoimmunity in children with autism
http://www.ncbi.nlm.nih.gov/pubmed/12145534
Autoimmune hazards of hepatitis B vaccine
http://www.sciencedirect.com/…/article/pii/S1568997204002010
Vaccine Model of Antiphospholipid Syndrome Induced by Tetanus Vaccine
http://lup.sagepub.com/content/21/2/195.abstract
Influenza vaccination can induce new-onset anticardiolipins but not ß2-glycoprotein-I antibodies among patients with systemic lupus erythematosus
http://lup.sagepub.com/content/21/2/168.abstract
Influenza and autoimmunity
http://onlinelibrary.wiley.com/…/j.1749-6632.2009.…/abstract
Systemic lupus erythematosus following HPV immunization or infection?
http://lup.sagepub.com/content/21/2/158.abstract
Early diphtheria-tetanus-pertussis vaccination associated with higher female mortality and no difference in male mortality in a cohort of low birthweight children: an observational study within a randomised trial
http://adc.bmj.com/…/20…/02/13/archdischild-2011-300646.full
Effects of diphtheria-tetanus-pertussis or tetanus vaccination on allergies and allergy-related respiratory symptoms among children and adolescents in the United States
http://www.ncbi.nlm.nih.gov/pubmed/10714532
Henoch–Schönlein purpura following meningitis C vaccination
http://rheumatology.oxfordjournals.org/content/40/3/345.full
Other Autoimmune Diseases
Characterization of antigen-presenting dendritic cells in the peripheral blood and colonic mucosa of patients with ulcerative colitis
http://www.ncbi.nlm.nih.gov/pubmed/11474315
Polymerase chain reaction detection of the hemagglutinin gene from an attenuated measles vaccine strain in the peripheral mononuclear cells of children with autoimmune hepatitis
http://www.springerlink.com/content/tln20u18374r4q30/
Early Childhood Membranous Nephropathy Due to Cationic Bovine Serum Albumin (Though not mentioned by the authors, Bovine Serum is in vaccines.)
http://www.nejm.org/doi/full/10.1056/NEJMoa1013792
The common immunogenic etiology of chronic fatigue syndrome: from infections to vaccines via adjuvants to the ASIA syndrome
http://www.ncbi.nlm.nih.gov/pubmed/22054760
General Autoimmunity Issues
Vaccines and autoimmunity
http://www.nature.com/…/jo…/v5/n11/abs/nrrheum.2009.196.html
Vaccine-induced Autoimmunity
http://www.sciencedirect.com/…/article/pii/S0896841196900918
Mechanisms of aluminum adjuvant toxicity and autoimmunity in pediatric populations
http://lup.sagepub.com/content/21/2/223.short
The Emerging Link Between Autoimmune Disorders and Neuropsychiatric Disease
This file is a PDF http://www.ncbi.nlm.nih.gov/…/PMC3086677/pdf/nihms284704.pdf
Serological association of measles virus and human herpesvirus-6 with brain autoantibodies in autism
http://www.ncbi.nlm.nih.gov/pubmed/9756729
Adjuvant Immunization Induces High Levels of Pathogenic Antiphospholipid Antibodies in Genetically Prone Mice: Another Facet of the ASIA Syndrome
http://lup.sagepub.com/content/21/2/210.abstract
Self-Organized Criticality Theory of Autoimmunity
http://www.plosone.org/…/info%3Adoi%2F10.1371%2Fjournal.pon…
Gut-Brain-Immune System Connection and Function Development
Autism: an emerging ‘neuroimmune disorder’ in search of therapy
http://informahealthcare.com/…/abs/10.1517/14656560903107789
Normal gut microbiota modulates brain development and behavior
http://www.pnas.org/content/108/7/3047.full
Novel roles for immune molecules in neural development: implications for neurodevelopmental disorders
(Many toxic insults discussed but not vaccines.)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059681/
Immune Proteins in Brain Development and Synaptic Plasticity
http://www.sciencedirect.com/…/article/pii/S0896627309006783
Function
Gastrointestinal Pathology in Autism Spectrum Disorders: The Venezuelan Experience
http://www.scribd.com/…/Gastrointestinal-Pathology-in-Autis…
Clinical Presentation and Histologic Findings at Ileocolonoscopy in Children with Autistic Spectrum Disorder and Chronic Gastrointestinal Symptoms
(Click “Download Paper” for full text)
http://www.la-press.com/clinical-presentation-and-histologi
Characterization of antigen-presenting dendritic cells in the peripheral blood and colonic mucosa of patients with ulcerative colitis
http://www.ncbi.nlm.nih.gov/pubmed/11474315
A possible central mechanism in autism spectrum disorders, part 1
http://www.ncbi.nlm.nih.gov/pubmed/19043938
A possible central mechanism in autism spectrum disorders, part 2: immunoexcitotoxicity
http://www.ncbi.nlm.nih.gov/pubmed/19161050
A possible central mechanism in autism spectrum disorders, part 3: the role of excitotoxin food additives and the synergistic effects of other environmental toxins
http://www.ncbi.nlm.nih.gov/pubmed/19284184
Efficacy of methylcobalamin and folinic acid treatment on glutathione redox status in children with autism
http://www.ajcn.org/content/89/1/425.long
Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2610366/
Oxidative stress-related biomarkers in autism: Systematic review and meta-analyses
http://www.sciencedirect.com/…/article/pii/S0891584912001827
Immune-glutamatergic dysfunction as a central mechanism of the autism spectrum disorders
http://www.benthamdirect.org/pages/content.php
Central and Peripheral Cytokines Mediate Immune-Brain Connectivity
http://www.springerlink.com/content/f6718rl3g2k75656/
No Antibodies Required For Immunity Against Some Viruses: B Cell Maintenance of Subcapsular Sinus Macrophages Protects against a Fatal Viral Infection Independent of Adaptive Immunity
http://www.cell.com/immunity/abstract/S1074-7613(12)00057-X
Immune Activation in Brain Aging and Neurodegeneration: Too Much or Too Little?
http://www.sciencedirect.com/…/article/pii/S0896627309006771
Connection
Autism: an emerging ‘neuroimmune disorder’ in search of therapy
http://informahealthcare.com/…/abs/10.1517/14656560903107789
Molecular mechanisms underlying anti-inflammatory phenotype of neonatal splenic macrophages
http://www.jleukbio.org/content/82/2/403.full.pdf+html
Central and Peripheral Cytokines Mediate Immune-Brain Connectivity
http://www.springerlink.com/content/f6718rl3g2k75656/
Children with autism spectrum disorders (ASD) who exhibit chronic gastrointestinal (GI) symptoms and marked fluctuation of behavioral symptoms exhibit distinct innate immune abnormalities and transcriptional profiles of peripheral blood (PB) monocytes
http://www.jni-journal.com/a…/S0165-5728(11)00191-3/abstract
Panenteric IBD-Like Disease in a Patient with Regressive Autism Shown for the First Time by the Wireless Capsule Enteroscopy: Another Piece in the Jigsaw of this Gut-Brain Syndrome?
http://www.nature.com/…/journ…/v100/n4/full/ajg2005166a.html
Clinical Presentation and Histologic Findings at Ileocolonoscopy in Children with Autistic Spectrum Disorder and Chronic Gastrointestinal Symptoms
(Click “Download Paper” for full text)
http://www.la-press.com/clinical-presentation-and-histologi
Effectiveness of the gluten-free, casein-free diet for children diagnosed with autism spectrum disorder:
(Based on parental report)
http://www.ncbi.nlm.nih.gov/pubmed/22564339
Hypothesis: Conjugate vaccines may predispose children to autism spectrum disorders
http://www.sciencedirect.com/…/article/pii/S0306987711004117
A possible central mechanism in autism spectrum disorders, part 1
http://www.ncbi.nlm.nih.gov/pubmed/19043938
A possible central mechanism in autism spectrum disorders, part 2: immunoexcitotoxicity
http://www.ncbi.nlm.nih.gov/pubmed/19161050
A possible central mechanism in autism spectrum disorders, part 3: the role of excitotoxin food additives and the synergistic effects of other environmental toxins
http://www.ncbi.nlm.nih.gov/pubmed/19284184
Immune-glutamatergic dysfunction as a central mechanism of the autism spectrum disorders
http://www.benthamdirect.org/pages/content.php
Immune Activation in Brain Aging and Neurodegeneration: Too Much or Too Little?
http://www.sciencedirect.com/…/article/pii/S0896627309006771
Autism
Metals and Environmental Toxins in Autism
Sorting out the spinning of autism: heavy metals and the question of incidence
This file is a PDF http://www.ane.pl/pdf/7021.pdf
Neurodevelopmental disorders following thimerosal-containing childhood immunizations: a follow-up analysis
http://www.ncbi.nlm.nih.gov/pubmed/15764492
A Case Series of Children with Apparent Mercury Toxic Encephalopathies Manifesting with Clinical Symptoms of Regressive Autistic Disorders
http://www.ncbi.nlm.nih.gov/pubmed/17454560
Persistent behavioral impairments and alterations of brain dopamine system after early postnatal administration of thimerosal in rats
http://www.ncbi.nlm.nih.gov/pubmed/21549155
Neonatal administration of thimerosal causes persistent changes in mu opioid receptors in the rat brain
http://www.ncbi.nlm.nih.gov/pubmed/20803069
Do aluminum vaccine adjuvants contribute to the rising prevalence of autism?
This file is a PDF http://omsj.org/reports/tomljenovic%202011.pdf
Administration of thimerosal to infant rats increases overflow of glutamate and aspartate in the prefrontal cortex: protective role of dehydroepiandrosterone sulfate
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264864/
Mercury in first-cut baby hair of children with autism versus typically-developing children
http://www.tandfonline.com/d…/abs/10.1080/02772240701699294…
Mercury induces inflammatory mediator release from human mast cells
http://www.biomedcentral.com/1742-2094/7/20
Maternal thimerosal exposure results in aberrant cerebellar oxidative stress, thyroid hormone metabolism, and motor behavior in rat pups; sex- and strain-dependent effects
http://www.ncbi.nlm.nih.gov/pubmed/22015705
How environmental and genetic factors combine to cause autism: A redox/methylation hypothesis
http://www.sciencedirect.com/…/article/pii/S0161813X0700215X
Comparison of blood and brain mercury levels in infant monkeys exposed to methylmercury or vaccines containing thimerosal
http://www.ncbi.nlm.nih.gov/pubmed/16079072
Integrating experimental (in vitro and in vivo) neurotoxicity studies of low-dose thimerosal relevant to vaccines
http://www.ncbi.nlm.nih.gov/pubmed/21350943
Thimerosal-Derived Ethylmercury Is a Mitochondrial Toxin in Human Astrocytes: Possible Role of Fenton Chemistry in the Oxidation and Breakage of mtDNA
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395253/
Neuroimmune Disorders in Autism
Influence of pediatric vaccines on amygdala growth and opioid ligand binding in rhesus macaque infants: A pilot study
This file is a PDF http://www.ane.pl/pdf/7020.pdf
Persistent behavioral impairments and alterations of brain dopamine system after early postnatal administration of thimerosal in rats
http://www.ncbi.nlm.nih.gov/pubmed/21549155
Neurodevelopmental disorders following thimerosal-containing childhood immunizations: a follow-up analysis
http://www.ncbi.nlm.nih.gov/pubmed/15764492
Neonatal administration of thimerosal causes persistent changes in mu opioid receptors in the rat brain
http://www.ncbi.nlm.nih.gov/pubmed/20803069
Abnormal measles-mumps-rubella antibodies and CNS autoimmunity in children with autism
http://www.ncbi.nlm.nih.gov/pubmed/12145534
Maternal thimerosal exposure results in aberrant cerebellar oxidative stress, thyroid hormone metabolism, and motor behavior in rat pups; sex- and strain-dependent effects
http://www.ncbi.nlm.nih.gov/pubmed/22015705
Serological association of measles virus and human herpesvirus-6 with brain autoantibodies in autism
http://www.ncbi.nlm.nih.gov/pubmed/9756729
Autism: an emerging ‘neuroimmune disorder’ in search of therapy
http://informahealthcare.com/…/abs/10.1517/14656560903107789
Administration of thimerosal to infant rats increases overflow of glutamate and aspartate in the prefrontal cortex: protective role of dehydroepiandrosterone sulfate.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264864/
A possible central mechanism in autism spectrum disorders, part 1
http://www.ncbi.nlm.nih.gov/pubmed/19043938
A possible central mechanism in autism spectrum disorders, part 2: immunoexcitotoxicity
http://www.ncbi.nlm.nih.gov/pubmed/19161050
A possible central mechanism in autism spectrum disorders, part 3: the role of excitotoxin food additives and the synergistic effects of other environmental toxins
http://www.ncbi.nlm.nih.gov/pubmed/19284184
Evidence of Mitochondrial Dysfunction in Autism and Implications for Treatment
This file is a PDF http://www.icdrc.org/documents/Mitoandautism2008.pdf
Neuroglial activation and neuroinflammation in the brain of patients with autism
http://www.ncbi.nlm.nih.gov/pubmed/15546155
Thimerosal-Derived Ethylmercury Is a Mitochondrial Toxin in Human Astrocytes: Possible Role of Fenton Chemistry in the Oxidation and Breakage of mtDNA
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395253/
Environment and Genetics in Autism
Genetic Heritability and Shared Environmental Factors Among Twin Pairs With Autism
http://archpsyc.jamanetwork.com/article.aspx
How environmental and genetic factors combine to cause autism: A redox/methylation hypothesis
http://www.sciencedirect.com/…/article/pii/S0161813X0700215X
Theoretical aspects of autism: Causes—A review
http://informahealthcare.com/…/abs/10.…/1547691X.2010.545086
Gastrointestinal Disease in Autism
Children with autism spectrum disorders (ASD) who exhibit chronic gastrointestinal (GI) symptoms and marked fluctuation of behavioral symptoms exhibit distinct innate immune abnormalities and transcriptional profiles of peripheral blood (PB) monocytes
http://www.jni-journal.com/a…/S0165-5728(11)00191-3/abstract
Panenteric IBD-Like Disease in a Patient with Regressive Autism Shown for the First Time by the Wireless Capsule Enteroscopy: Another Piece in the Jigsaw of this Gut-Brain Syndrome?
http://www.nature.com/…/journ…/v100/n4/full/ajg2005166a.html
Clinical Presentation and Histologic Findings at Ileocolonoscopy in Children with Autistic Spectrum Disorder and Chronic Gastrointestinal Symptoms
(Click “Download Paper” for full text)
http://www.la-press.com/clinical-presentation-and-histologi
Gastrointestinal Pathology in Autism Spectrum Disorders: The Venezuelan Experience
http://www.scribd.com/…/Gastrointestinal-Pathology-in-Autis…
Autistic enterocolitis: Fact or fiction?
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694587/
Autistic Enterocolitis: Confirmation of a New Inflammatory Bowel Disease in An Italian Cohort of Patients
http://www.latitudes.org/forums/index.php?showtopic=1409
Specific Vaccines and Autism
Abnormal measles-mumps-rubella antibodies and CNS autoimmunity in children with autism
http://www.ncbi.nlm.nih.gov/pubmed/12145534
Hypothesis: Conjugate vaccines may predispose children to autism spectrum disorders
http://www.sciencedirect.com/…/article/pii/S0306987711004117
Hepatitis B Vaccination of Male Neonates and Autism, NHIS 1997–2002
http://www.tandfonline.com/…/p…/10.1080/15287394.2010.519317
Elevated levels of measles antibodies in children with autism
http://www.sciencedirect.com/…/article/pii/S0887899402006276
Methylation in Autism
Efficacy of methylcobalamin and folinic acid treatment on glutathione redox status in children with autism
http://www.ajcn.org/content/89/1/425.long
Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2610366/
Oxidative stress-related biomarkers in autism: Systematic review and meta-analyses
http://www.sciencedirect.com/…/article/pii/S0891584912001827
How environmental and genetic factors combine to cause autism: A redox/methylation hypothesis
http://www.sciencedirect.com/…/article/pii/S0161813X0700215X
Thimerosal-Derived Ethylmercury Is a Mitochondrial Toxin in Human Astrocytes: Possible Role of Fenton Chemistry in the Oxidation and Breakage of mtDNA
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395253/
Unexplained Infant Death
Infant mortality rates regressed against number of vaccine doses routinely given: is there a biochemical or synergistic toxicity?
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170075/
Primary Immunization of Premature Infants with Gestational Age <35 Weeks: cardiorespiratory Complications and C-Reactive Protein Responses Associated with Administration of Single and Multiple Separate Vaccines Simultaneously
http://www.jpeds.com/article/S0022-3476(07)00185-0/abstract
Unexplained cases of sudden infant death shortly after hexavalent vaccination
http://www.sciencedirect.com/…/article/pii/S0264410X05004688
Unexplained cases of sudden infant death shortly after hexavalent vaccination – rebuttal
http://www.murciasalud.es/archivo.php?id=88521
Simultaneous sudden infant death syndrome
http://www.ncbi.nlm.nih.gov/pubmed/17654772
Treatment of lethal pertussis vaccine reaction with histamine H1 antagonists.
http://www.neurology.org/content/37/6/1068
Murine model for pertussis vaccine encephalopathy: linkage to H-2.
http://www.nature.com/…/journal/v299/n5885/abs/299738a0.html
Chronic Illness
Emergent Human Pathogen Simian Virus 40 and Its Role in Cancer
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC452549/
‘ASIA’ – autoimmune/inflammatory syndrome induced by adjuvants
http://www.ncbi.nlm.nih.gov/pubmed/20708902
The common immunogenic etiology of chronic fatigue syndrome: from infections to vaccines via adjuvants to the ASIA syndrome
http://www.ncbi.nlm.nih.gov/pubmed/22054760
Aluminum as an adjuvant in Crohn’s disease induction
http://lup.sagepub.com/content/21/2/231.abstract
Aluminum is a potential environmental factor for Crohn’s disease induction: extended hypothesis
http://www.ncbi.nlm.nih.gov/pubmed/17804561
Characterization of antigen-presenting dendritic cells in the peripheral blood and colonic mucosa of patients with ulcerative colitis
http://www.ncbi.nlm.nih.gov/pubmed/11474315
The relationship between vaccine refusal and self-report of atopic disease in children
http://www.sciencedirect.com/…/article/pii/S0091674905000266
Antibodies to Saccharomyces cerevisiae in Crohn’s disease: Higher titers are associated with a greater frequency of mutant NOD2/CARD15 alleles and with a higher probability of complicated disease
http://onlinelibrary.wiley.com/doi/10.1002/ibd.20031/full
This item pairs with the link just above: The antigen is harvested and purified from fermentation cultures of a recombinant strain of the yeast Saccharomyces cerevisiae
This file is a PDF http://www.merck.com/…/pi…/r/recombivax_hb/recombivax_pi.pdf
Thimerosal-Derived Ethylmercury Is a Mitochondrial Toxin in Human Astrocytes: Possible Role of Fenton Chemistry in the Oxidation and Breakage of mtDNA
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395253/
Viral Infection and Neurologic Dysfunction
Antibodies to measles in individuals with recent onset psychosis
http://www.schres-journal.com/…/S0920-9964(09)0060…/abstract
Elevated levels of measles antibodies in children with autism
http://www.pedneur.com/artic…/S0887-8994(02)00627-6/abstract
The human endogenous retrovirus link between genes and environment in multiple sclerosis and in multifactorial diseases associating neuroinflammation
http://www.ncbi.nlm.nih.gov/pubmed/19697163
Endogenous retroviral genes, Herpesviruses and gender in Multiple Sclerosis
http://www.ncbi.nlm.nih.gov/pubmed/19447411
Endogenous retrovirus type W GAG and envelope protein antigenemia in serum of schizophrenic patients
http://www.ncbi.nlm.nih.gov/pubmed/18760403
The multiple sclerosis-associated retrovirus and its HERV-W endogenous family: a biological interface between virology, genetics, and immunology in human physiology and disease
http://www.ncbi.nlm.nih.gov/pubmed/19039700
Infection and Autoimmunity
http://wwwnc.cdc.gov/eid/article/12/3/05-1409_article.htm
The common immunogenic etiology of chronic fatigue syndrome: from infections to vaccines via adjuvants to the ASIA syndrome
http://www.ncbi.nlm.nih.gov/pubmed/22054760
Influenza and autoimmunity
http://onlinelibrary.wiley.com/…/j.1749-6632.2009.…/abstract
Subacute sclerosing panencephalitis–the continuing threat
(cut and paste link to download PDF)
hrcak.srce.hr/file/43654
Other Complications Post Vaccination
Emergent Human Pathogen Simian Virus 40 and Its Role in Cancer
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC452549/
Adverse Events following 12 and 18 Month Vaccinations: a Population-Based, Self-Controlled Case Series Analysis
http://www.plosone.org/…/info%3Adoi%2F10.1371%2Fjournal.pon…
Increased Incidence and Clinical Picture of Childhood Narcolepsy following the 2009 H1N1 Pandemic Vaccination Campaign in Finland
http://www.plosone.org/…/info%3Adoi%2F10.1371%2Fjournal.pon…
Henoch–Schönlein purpura following meningitis C vaccination
http://rheumatology.oxfordjournals.org/content/40/3/345.full
Fatal outcome after postexposure rabies vaccination in a patient with Parkinson’s disease
http://www.ncbi.nlm.nih.gov/pubmed/15675624
Discolored Leg Syndrome Following Vaccines:
http://www.ncbi.nlm.nih.gov/pubmed/18546020
Adverse Effects of Vaccines: Evidence and Causality
(From the text: The committee finds that evidence convincingly supports a causal relationship between some vaccines and some adverse events…evidence favors rejection of five vaccine-adverse event relationships… However, for the majority of cases (135 vaccine-adverse event pairs), the evidence was inadequate to accept or reject a causal relationship.”
http://www.iom.edu/…/Adverse-Effects-of-Vaccines-Evidence-a…
Vaccination Efficacy, Failure, and Disease Transmission
Disease Transmission
Attenuated vaccines can recombine to form virulent field viruses
http://www.sciencemag.org/content/337/6091/188.abstract
Sibling Transmission of Vaccine-Derived Rotavirus (RotaTeq) Associated With Rotavirus Gastroenteritis
This file is a PDF http://pediatrics.aappublications.org/…/peds.2009-1901.full…
The Evolutionary Consequences of Blood-Stage Vaccination on the Rodent Malaria Plasmodium chabaudi
http://www.plosbiology.org/…/info%3Adoi%2F10.1371%2Fjournal…(Ambra+-+Biology+New+Articles
Vaccine-acquired Rotavirus Infection in Two Infants with Severe Combined Immunodeficiency
http://www.jacionline.org/ar…/S0091-6749(09)00151-1/fulltext
Long-Term Circulation of Vaccine-Derived Poliovirus That Causes Paralytic Disease
http://jvi.asm.org/content/76/13/6791.full
Molecular and Antigenic Characterization of a Highly Evolved Derivative of the Type 2 Oral Poliovaccine Strain Isolated from Sewage in Israel
http://jcm.asm.org/content/38/10/3729.full
Prevalence of vaccine-derived polioviruses in the environment
http://jgv.sgmjournals.org/content/83/5/1107.full
Transmission of mumps virus from mumps-vaccinated individuals to close contact
http://www.ncbi.nlm.nih.gov/pubmed/21983359
Adventitious Agents and Vaccines
http://www.ncbi.nlm.nih.gov/…/a…/PMC2631857/pdf/11485673.pdf
Efficacy Issues/Failure
Why Do Pertussis (Whooping Couvh) Vaccines Fail?
http://pediatrics.aappublications.org/conte…/…/5/968.extract
Unexpectedly limited durability of immunity following acellular pertussis vaccination in preadolescents in a North American outbreak
http://cid.oxfordjournals.org/content/54/12/1730.abstract
Selection of Hepatitis B Virus (HBV) Vaccine Escape Mutants in HBV-Infected and HBV/HIV-Coinfected Patients Failing Antiretroviral Drugs With Anti-HBV Activity
http://journals.lww.com/…/Selection_of_Hepatitis_B_Virus__H…
Measles outbreak in a fully immunized secondary-school population
http://www.ncbi.nlm.nih.gov/pubmed/3821823
Acellular pertussis vaccination facilitates Bordetella parapertussis infection in a rodent model of bordetellosis.
http://www.ncbi.nlm.nih.gov/pubmed/20200027
Mumps outbreak among vaccinated university students associated with a large party, the Netherlands, 2010
http://www.sciencedirect.com/…/article/pii/S0264410X12006299
Waning Protection after Fifth Dose of Acellular Pertussis Vaccine in Children
http://www.nejm.org/doi/full/10.1056/NEJMoa1200850
Review of the United States universal varicella vaccination program: Herpes zoster incidence rates, cost-effectiveness, and vaccine efficacy based
primarily on the Antelope Valley Varicella Active Surveillance Project data
http://www.sciencedirect.com/…/article/pii/S0264410X12007761
Effectiveness of Jeryl Lynn-containing vaccine in Spanish children
http://www.ncbi.nlm.nih.gov/pubmed/19356610
Mumps Orchitis in the Post-Vaccine Era (1967Y2009)
This file is a PDF http://www.vaccine-tlc.org/docs/Mumps.pdf
Considerations for Viral Disease Eradication: Lessons Learned and Future Strategies
Quote: Important and often overlooked, mass vaccinations itself can also exert tremendous selective pressures and lead to the evolution of new infectious agents.
http://books.nap.edu/openbook.php?record_id=10424&page=R1
Recent Resurgence of Mumps in the United States
http://www.nejm.org/doi/full/10.1056/NEJMoa0706589#t=article
Risk of vaccine failure after Haemophilus influenzae type b (Hib) combination vaccines with acellular pertussis
http://www.thelancet.com/…/PIIS0140-6736(03)13171-6/fulltext
Subacute sclerosing panencephalitis–the continuing threat
(cut and paste link to download PDF)
http://www.hrcak.srce.hr/file/43654
Questionable Science and Policy
Placebos
What’s in Placebos: Who Knows? Analysis of Randomized, Controlled Trials
http://www.ncbi.nlm.nih.gov/pubmed/20956710
Testing vaccines in pediatric research subjects
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831649/
Policy
Adverse Effects of Vaccines: Evidence and Causality
(From the text: The committee finds that evidence convincingly supports a causal relationship between some vaccines and some adverse events…evidence favors rejection of five vaccine-adverse event relationships… However, for the majority of cases (135 vaccine-adverse event pairs), the evidence was inadequate to accept or reject a causal relationship.”
http://www.iom.edu/…/Adverse-Effects-of-Vaccines-Evidence-a…
Human papillomavirus (HPV) vaccine policy and evidence-based medicine: Are they at odds?
http://informahealthcare.com/…/abs/10.…/07853890.2011.645353
The Number Needed to Vaccinate to Prevent Infant Pertussis Hospitalization and Death Through Parent Cocoon Immunization
http://cid.oxfordjournals.org/…/…/12/01/cid.cir836.abstract…
The Evolutionary Consequences of Blood-Stage Vaccination on the Rodent Malaria Plasmodium chabaudi
http://www.plosbiology.org/…/info%3Adoi%2F10.1371%2Fjournal…(Ambra+-+Biology+New+Articles
Selection of Hepatitis B Virus (HBV) Vaccine Escape Mutants in HBV-Infected and HBV/HIV-Coinfected Patients Failing Antiretroviral Drugs With Anti-HBV Activity
http://journals.lww.com/…/Selection_of_Hepatitis_B_Virus__H…
Influenza Vaccination During Pregnancy: A Critical Assessment of the Recommendations of the Advisory Committee on Immunization Practices (ACIP)
http://www.jpands.org/vol11no2/ayoub.pdf
Review of the United States universal varicella vaccination program: Herpes zoster incidence rates, cost-effectiveness, and vaccine efficacy based primarily on the Antelope Valley Varicella Active Surveillance Project data http://www.sciencedirect.com/…/article/pii/S0264410X12007761
Adverse events and quadrivalent human papillomavirus recombinant vaccine
http://jama.jamanetwork.com/article.aspx
Attenuated vaccines can recombine to form virulent field viruses
http://www.sciencemag.org/content/337/6091/188.abstract
Mandatory HPV Vaccination
http://jama.jamanetwork.com/article.aspx?articleid=1104867
Acellular pertussis vaccination facilitates Bordetella parapertussis infection in a rodent model of bordetellosis.
http://www.ncbi.nlm.nih.gov/pubmed/20200027
No autoimmune safety signal after vaccination with quadrivalent HPV vaccine Gardasil?
http://tinyurl.com/72uvrb2
Influenza vaccination: policy versus evidence
http://www.bmj.com/content/333/7574/912%2523TBL2.full
Human papillomavirus vaccine trials in India
http://www.thelancet.com/…/PIIS0140-6736(11)60270-5/fulltext
Australia suspends seasonal flu vaccination of young children
http://www.bmj.com/content/340/bmj.c2419
Australia suspends seasonal flu vaccination of young children
http://www.bmj.com/…/adverse-events-following-influenza-vac…
Child influenza vaccination: Ramifications of adverse events in children in Australia
http://www.bmj.com/content/340/bmj.c2994
Vaccine safety: current systems and recent findings
http://journals.lww.com/…/Vaccine_safety__current_systems_a…
Excess mortality from seasonal influenza is negligible below the age of 50 in Israel: implications for vaccine policy
http://www.springerlink.com/content/2p44p50005827585/
Adventitious Agents and Vaccines
http://www.ncbi.nlm.nih.gov/…/a…/PMC2631857/pdf/11485673.pdf
Why Do Pertussis Vaccines Fail?
http://pediatrics.aappublications.org/conte…/…/5/968.extract
Vaccine Contamination
Mercury in vaccines from the Australian childhood immunization program schedule
http://www.ncbi.nlm.nih.gov/pubmed/20391108
Quantitation of DNA and Protein Impurities in Biopharmaceuticals -Liver Cancer?
http://pubs.acs.org/doi/abs/10.1021/ac00009a003
Cloned Hepatitis B Virus DNA causes hepatitis in chimpanzees
This file is a PDF http://www.nature.com/natu…/journal/…/n5885/pdf/299740a0.pdf
The Dangerous Impurities of Vaccines
http://www.scribd.com/patro…/d/49973741-Dangerous-Impurities
Adventitious Agents and Vaccines
http://www.ncbi.nlm.nih.gov/…/a…/PMC2631857/pdf/11485673.pdf
Veterinary Research
Attenuated vaccines can recombine to form virulent field viruses
http://www.sciencemag.org/content/337/6091/188.abstract
Vaccine-associated acute polyneuropathy resembling Guillain-Barré syndrome in a dog
http://www.mendeley.com/…/vaccineassociated-acute-polyneur…/
Viral status and antibody response in cattle inoculated with recombinant bovine leukemia virus-vaccinia virus vaccines after challenge exposure with bovine leukemia virus-infected lymphocytes
http://www.ncbi.nlm.nih.gov/pubmed/8725805
Interesting Articles, etc.
Vaccines for Children Program: Vulnerabilities in Vaccine Management
http://oig.hhs.gov/oei/reports/oei-04-10-00430.pdf
Guide to Vaccine Contraindications and Precautions – CDC
http://www.cdc.gov/…/downlo…/contraindications-guide-508.pdf
Charts Comparing Dead Babies to Vaccine Timeline:
http://therefusers.com/…/dead-babies-and-stillbirths-repor…/
Unvaccinated Children Are Healthier
This file is a PDF http://www.vaccineinjury.info/imag…/stories/ias1992study.pdf
State of health of unvaccinated children
http://www.vaccineinjury.info/…/survey-results-illnesses.ht…
Interview with PhD Immunologist, Dr Tetyana Obukhanych- part 1, by Catherine Frompovich
http://tinyurl.com/7guruq6
Vaccines Backfire: Veterinary Vaccines Found to Combine Into New Infectious Viruses
http://www.sciencedaily.com/releases/2012/…/120712144754.htm
A National and State Profile of Leading Health Problems and Health Care Quality for US Children: Key Insurance Disparities and Across-State Variations
http://www.sciencedirect.com/…/article/pii/S1876285910002500
The Questionable Contribution of Medical Measures to the Decline of Mortality in the United States in the Twentieth Century
This file is a PDF http://www.columbia.edu/…/clie…/readings/week_2/mckinlay.pdf
High Rate of Acellular Pertussis Vaccine Failure in Pre-Adolescents in a North American Outbreak
This file is a PDF http://www.immunizeca.org/…/CIC-2012-Sum…/Presenter-Witt.pdf
Aluminum in vaccines may be linked to health risks
http://www.straight.com/…/aluminum-vaccines-may-be-linked-h…
Vaccine-Nation: ‘Globally-supported company is funding fatal polio shots:
http://tribune.com.pk/…/vaccine-nation-globally-supported-…/
FDA 21 CFR Part 630, [Docket No. 84N-0178] Additional Standards for Viral Vaccines; Poliovirus Vaccine, Live, Oral: “However, although the continued availability of the vaccine may not be in immediate jeopardy, any possible doubts, whether or not well founded, about the safety of the vaccine cannot be allowed to exist”
(See last page, top of middle column: click top link to download)
http://tinyurl.com/88k77o4
A Judicial Watch Special Report: Examining the FDA’s HPV Vaccine Records
This file is a PDF http://www.judicialwatch.org/…/JWReportFDAhpvVaccineRecords…
Live virus used in polio vaccine can evolve and infect, warns TAU researcher
http://www.news-medical.net/…/Live-virus-used-in-polio-vacc…
The Present Status of Polio Vaccines – Transcript published in Illinois Medical Journal
http://s45.photobucket.com/…/Ang…/Present%20Status%20Polio/…
Recombinant HPV DNA found in multiple samples of Gardasil
http://sanevax.org/sane-vax-to-fda-recombinant-hpv-dna-fou…/
Warning bells against HPV vaccines (Rate of cervical cancer in US is about 3 per 100,000)
http://www.dailymail.co.uk/…/Warning-bells-HPV-vaccines.htm…
Lies, Damned Lies, and Medical Science
http://www.theatlantic.com/…/lies-damned-lies-and-med…/8269/
Response to influenza vaccine in adjuvant 65-4
(Peanut oil used as an adjuvant)
This file is a PDF http://www.ncbi.nlm.nih.gov/…/PMC213…/pdf/jhyg00071-0101.pdf
Gut Inflammation and Autism
http://the-scientist.com/2011/02/01/opening-a-can-of-worms/
Vaccine and medication safety are parents’ top research priorities
http://www2.med.umich.edu/prmc/media/newsroom/details.cfm
Thomson Reuters-NPR health poll: Vaccines
http://healthcare.thomsonreuters.com/…/NPR_report_vaccines.…
Alternative Vaccination Schedule Preferences Among Parents of Young Children
http://pediatrics.aappublications.org/conte…/…/848.abstract…
Frequency of Alternative Immunization Schedule Use in a Metropolitan Area
http://pediatrics.aappublications.org/…/peds.2011-3154.abst…
Italian court reignites MMR vaccine debate after award over child with autism
http://tinyurl.com/bvo2puj
States ending free parent whooping vaccine
http://www.news.com.au/…/state…/story-e6frfku0-1226350174856
Public Accounts and Estimates Committee – Ending Cocooning for Whooping Cough – Committee Testimony – see pgs 26-27
http://www.parliament.vic.gov.au/…/PAEC_Budget_estimates_12…
Three Young People From the Same Danish Town Have All Suffered Loss of Hearing in the Aftermath of MMR-Vaccination
http://nbjour.wordpress.com/…/three-young-people-from-the-…/
The Insanity Virus
http://discovermagazine.com/…/03-the-insanity…/article_view…
Potential Role of Parents’ Work Exposures in Autism Risk Examined: Possible Link Between Some Work Exposures and Risk for Offspring
http://www.sciencedaily.com/releases/2012/…/120312113902.htm
Vaccine bombshell: Baby monkeys given standard doses of popular vaccines develop autism symptoms
http://www.naturalnews.com/035787_vaccines_autism_monkeys.h
Merck & Co., Inc.: Lawsuit Claims Merck Overstated Mumps Vaccine Effectiveness
http://tinyurl.com/7j877qk
A Drumbeat on Profit Takers
http://www.nytimes.com/…/…/a-drumbeat-on-profit-takers.html…
Recommendation to place a moratorium on aluminum in vaccines in France by French Assembly Committee
This file is a PDF http://pdf.20mn.fr/2012/autres/ge-vaccination.pdf
google translation:
This file is a PDF http://translate.google.com/translate
What lies behind the low rates of vaccinations among nurses who treat infants?
This file is a PDF http://www.vaccineliberationarmy.com/…/What-lies-behind-the…
Amish farm kids remarkably immune to allergies: study
http://www.reuters.com/…/us-kidsallergies-idUSBRE8431J92012…
Vaccines for Children Program: Vulnerabilities in Vaccine Management
This file is a PDF http://oig.hhs.gov/oei/reports/oei-04-10-00430.pdf

“I wish someone had told me that before I graduated”

Recently someone asked me to write a chapter in a book for new Veterinary graduates.
I thought it might be useful for many people of different walks of life, so here are my
TIWI KWIP’s — This cone of shame is a mnemonic word that specialists and “older” vintage  practitioners use to explain “Things I Wish I Knew When I was in Practice”
 I always enjoy listening to these lecturers, as their stories given with their “retrospectroscope” are illuminating and often a relief to hear that others had gone through your situation, bringing some hilarity to our subjective failings .  For instance the Professor of anaesthesiology was lecturing to us and relayed a humorous story about an Anaesthetist climbing the long ladder to heaven after he had passed away.  There was a long chalkboard next to the ladder, and after each step you had to place a chalk mark  next to the ladder for any mistakes you made in your life or any work related mishaps.  On his way up he met a surgeon he knew coming down, and he was surprised and somewhat concerned to see that this surgeon was heading the wrong way! “Hey, are you ok? Did you get rejected at the pearly gates?” he asked. “No, I just ran out of chalk, I’m coming down to get some more!” the surgeon said.
I hope, as you travel through your working life, that you realize that all the great Veterinarians that you respect, and that have gone before you, are there because they never gave up, and that they probably made all the mistakes that you perhaps will, or are going through right now.  Your licence to “practice” means just that- you will forever be “practicing” and learning. Listen to your colleagues, listen to your clients, avoid becoming judgemental, stay humble.  You are still the top of your High School league, and necessarily in the top 1% academically, so be aware that Veterinary Medicine and Surgery is not always clear sailing, and it is not always your fault. This does not mean that you shouldn’t acknowledge anything that did not go 100% smoothly, but remind yourself, and your clients, that we are dealing with biology, not changing an old tyre, and we cannot guarantee immortality at any cost. We can only do our best, with our heartfelt desire to help. The vast majority of our work will be an improvement for their pet, and we are definitely more knowledgeable than any other non- veterinarian out there giving advice on pet care.
There will be  many moments of mild, or even severe anxiety,  and several periods of doubt, during your first few years as a Veterinary Surgeon and Physician.  You will gain experience. Keep moving and seek help if you are feeling overwhelmed- because it’s actually a normal part of the process!  Many “disasters” are actually a lesson which in the future will help you to help someone else.  Cherish those, and remind yourself how well you recovered from that situation. Save your client thank you notes, and refer to the many outstanding successes you have had if you ever find yourself feeling down about your profession.
sunrise boys

First off remember that you are NOT ALONE.  You really do have friends and family that care, just go and find them.   Get social.  Talk to PEOPLE.  Off load your grief. The rate of suicide in the veterinary profession is unacceptably high.  It has been shown that those  vets who have a more balanced life, with a social supporting structure such as church, drama clubs, book clubs, soccer, netball, football have much less stress related illness. Exercise based activities that are routinely added to your week are a survival mechanism, it might seem a chore but just DO IT!  Find your TRIBE, so you have a sense of purpose and belonging. Tribes exist online (Facebook) and in real time in your community, its the niche- doing what you like together with a small group.
1) Develop an attitude of gratitude towards your boss and nurses. Bring food to share!  When you graduate you do not know everything and the nurses and staff often know a heck of a lot more than you. Be kind to the nurses especially, some of them may not seem worth it (they get stressed by new grads) but time will pass and you will improve.
2) Expect the unexpected– re spay– plan everything well, and something will happen that you didn’t expect, but don’t feel bad about that because next time you will do that better.   Everyone drops a spay pedicle in their first year, don’t panic, extend the incision and find the kidney in that area, its right under it.   Exteriorize and have good vision of the tract.  Don’t use thin  monofilament suture around the uterine stump in fat/peri-oestrous  as when the swelling happens (as it always does post) the material will cut into the tissue and the animal can bleed out from there.
3)  There are always more options than what you have been taught at Uni, consider referring if you are stumped- no shame in that: ophthalmology, Dentistry, Dermatologist, Internist referral, also “alternative medicine” to a qualified veterinarian trained in acupuncture, Chinese herbs, western herbs, essential oils, remedial massage, chiropractic, osteopathy- refer to your colleagues it will make you look AWESOME. (not dumb) if you get a patient that you cannot think of a way forward.  Visit your colleagues and watch them practice, see if you can be a trainee under their mentorship. Join the local journal club.
4) FAMILY first!  Make time for dating and looking after your partner and plan family fun times- your family is more important than work. However if they are very “needy” you might have to put in place some outside help, eg. if you are caring for elderly parents, an autistic child, or disabled partner, you need back up plans for when you are scheduled to work.  I have been both employer and employee, and understand both sides, however if an employer is looking after an family crisis member and their casual staff calls in at the last minute repeatedly to say they cannot work because their child has a head cold and cannot go to school – you can understand that this is really not the employer’s problem, even if government regulations in the workplace industry might allow some time off for parental leave. It’s important to be thoughtful of your colleague’s time.  Be kind to your workplace and have babysitters lined up to cover these incidences. There are paid agencies such as “Dial an Angel” and lovely grandmothers nearby, figure it out in advance, prior to your need!
Remember the saying “if you fail to plan, you are planninbaristag to fail”. Plan to make time for your family and help the practice plan to give you time off.
5) Nutrition! Don’t skip breakfast! Have 1gm of protein/kg of your body weight every day. If you  need to have a smoothie on the run, then do that. Plan nutritious stews for evening meals, a slow cooker and a rice cooker with steaming basket on top are essential to your growing family. Throw everything in the crockpot before you go to bed, and its done for the day!
6) Do 7 minutes of exercise everyday- this could be 1 minute of push ups, 1 minute of star jumps, 1 minute of planking, 1 minute of running on the spot, 1 minute of stair climbs and 1 minute each of side planking
fatcatI’m in shape! (Round is a shape, right?)You can watch the morning news while doing this.

7) Find a hobby- art, painting, pottery, snorkeling etc- you need to put GOOD pictures into your brain daily, to wipe out or replace the BAD pictures that will come in- the Hit by cars, the emotional client that blames you (incorrectly usually!) for not picking up their pets disease, the euthenasia where everyone cries etc- these all affect your adrenals and will give you a type of Post Traumatic Stress Disorder or PTSD.  You need to file these away and calm your hormones. Reset your Parasympathetic gut healing and remove the cortisol/adrenal rush.
8) See a Qualified Naturopath and an Integrative GP doctor–and ask for a referral to a specialist if necessary,  to help you cope and find strategies, supplements, and diet advice to get you back on track if you are feeling not quite 100%
9)  SMILE! It’s contagious–Do IT- even if you don’t feel like it. Be happy.  It is a choice.  Learn to meditate on that.
smile pup
Good luck and be well, go for the long haul– life journey!
Feel free to pop over to my wellness sites for more advice. https://www.facebook.com/Naturopathvet?fref=ts
Naturopathvet.com
Dr Elaine Cebuliak
Get your antioxidants in early in the day, and take large quantities!

Get your antioxidants in early in the day, and take large quantities!

ANIMAL WELLNESS ph 61 7 31221997
Veterinary Integrative Care Clinic AND Advanced Veterinary Dentistry
Greenslopes Shopping Mall
Shop 6B/700 Logan Road,
Greenslopes Qld 4120
www.animalwellness.com.au
http://www.facebook.com/?ref=home#!/animalwellness

https://naturopathvet.com/

Dr Elaine Cebuliak BVSc MACVSc dentistry, Dip Ed, Dip Rem Massage, Cert Chinese Herbs, Cert IVAS Qual Acupuncture, CMAVA, Adv Dip Naturopathy, Adv Dip Herbal Med, Adv Dip Nutrition       ph 61-422413404
http://www.pethealth.com.au/Page/animal-massage-brisbane

The Angelina Jolie factor & Ovarian Cancer: Risks, Genetics, epigenetics and nutrigenomics

We have all heard about the famous and beautiful actress Angelina Jolietmb_173x173_angelina-jolie-parenting-21may14-01 having taken the preventative steps of having her breasts, and now her ovaries surgically removed due to the presence of her cancer causing genetic roulette make up. She made this decision after careful consultation with her medical advisors, and after watching her mother die of the same genetic cancer.  She is such an admirable and gifted human being with otherwise an amazing genetic makeup.  It takes us aback with this news to appreciate that she really is, indeed, human.
Many of you readers may have formed an opinion about this. Some have voiced disappointment in the media hype with their pontificating on conspiracy theories. That is “she was manipulated by big pharma” or having surgery to improve the coffers of the Medical establishment etc. this quite frankly does not make sense. There is very little pharmacy associated with surgical healing compared to cancer chemotherapy. It’s actually a much more straightforward procedure. Even a complete ovariohysterectomy is only a few days in hospital.  I am sure that a woman of such high regarded stature would have had excellent medical advice and care. It is very likely that she will also partake of nutritional medicine, including herbs and  antioxidant therapies replete in omega 3 rich meals.  Integrative medical care in the United States is much more advanced than here in Australia, although we do have the Olivia Newton John Hospital opening in Victoria.  http://www.austin.org.au/cancer/
Others are saying that she was not given adequate informed holistic advice, otherwise why would she have surgery, especially if her organs were not shown to be cancerous. I think this too is unlikely.  Angelina and her family are well connected and intelligent people.
It’s more likely that the general public is less informed.
Having just returned from a visit with the senior professor in oncological gynecology, Professor Obermair http://www.obermair.info/inform…/gynaecological-cancer/… I think I can speak from the medically established  point of view given the latest research which puts some women (with the bad BRAC1&2)  somewhere between 30-80% certain to have ovarian cancer at some stage in their future if they carry a percentage, in total summation of genetic markers called SNP’s, that  produce the overall risk factor.
Ovarian cancer is insidious, and by the time it is diagnosed it is usually too late to save those precious mothers, wives and daughters. . It’s a difficult diagnosis to make, the signs and symptoms are not specific-and the cancer markers CA125 and HE4 are not 100% sensitive or specific. Therefore– speaking from the specialists:  it is simply an unacceptable risk if you have the strong SNP BRAC 1 and BRAC 2. End of discussion. Take it out, end of future risk.

As a veterinary surgeon who has performed thousands of ovariohysterectomies  and indeed some lifesaving surgeries, (pyometron, leiomyoma, adenocarcinoma) I can see their point.

I think it is most likely that Angelina had the best advice – she seems level headed and a smart cookie- and am confident it wasn’t about cosmetics. The public are probably not generally knowledgeable about the serum markers and DNA tests, as this is relatively new technology.  Given that her mother died a horrible death from this and that we are not privy to her exact BRCA figures, we are the uninformed. 

Because she is a public figure we can question her choice, but its likely that she did not have much choice from a statistic and genetic understanding. No doubt she will continue on with herbal, and nutritional supplementation, as did Olivia Newton John and all others. If Angelina had even a small cystic change on her ovaries, she would have been advised that there is no way to tell if this benign change could not become cancerous, and by the time it is “watched for change” it is often too late and peritoneal metastatases have spread. That is the dilemma in this diagnostic plan. You can read some more about it here:http://www.obermair.info/…/gynaecolo…/ovarian-cancer/…

Gynaecological Cancer Uterine Cancer In Australia, uterine cancer is the most common gynaecological cancer with more than 2000 women newly diagnosed every year. Typically it is a disease of postmenopausal women. Fibroids can become cancerous.  Ovarian cysts can become cancerous.

 I think the real point is that there is a lot more to understand about the intricacies now known regarding BRCA genes.

The SNP pedia explains the genetics in some detail, and it turns out that “23 and me ” saliva test is actually not as accurate as one would hope. There are over 2 thousand genetic markers when considering the 2 BRCA types. For the cancer markers 1+2 SNPedia currently contains 1456 BRCA1 SNPs and 1497 BRCA2 SNPs. Some of the variations in these genes are linked to Breast cancer and ovarian cancer, and other variations are benign. (See also BRCA1 and BRCA2 for individual gene discussions and links).
Microarray platforms used by DTC genomics testing companies such as FamilyTree DNA and 23andMe usually test a subset of substantially less than 100 BRCA1 or BRCA2 SNPs, typically, the most common ones. This results in both false positives (which includes being found positive for a variation that’s benign) as well as false negatives (the person tested carries a bad mutation, but it won’t be found since it’s one of the many SNPs that aren’t actually tested.
Having just researched and gone over the “23 and me” genomics (you can read about testing yourself here: https://www.23andme.com/)   I think it is not as simple as black and white, “it is what it is” does not explain the complex interaction of multiple genes…that is people on the outside (not being privy to geneticists, medical teams and the individuals circumstances) and without that genetic map knowledge might lump everyone into yay or nay piles. Diet and preventative measures are helpful FOR SOME, but they have a poorer probability of cancer reversal for others. Its not as simple as “you have BRAC1 gene so you must chop off your breasts”. There are thousands of genes with several of them interacting to set off or disallow the telomerase/cancer restriction to occur. Its actually more like a calculus problem, with many arithmetic variations and its very complex. One can have a multiplying variation of cancer causing genes which factor into the equation. As we age and our telomeres contract (its inevitable really, none of us get out of this life alive in the end!) our natural killer cells and immune system struggles. If you have a few SNPs that code for cancer they may increase your risk with age to an unacceptable level.( http://www.snpedia.com/index.php/Rs1042838)  This predisposition may rear its ugly head at any time- its like a time bomb.. Surgical removal of the offending, out of control tissue is a realistic option and is likely life saving for some. Not everyone will need to do this procedure, but for those with the 80% risk factors its definitely something to consider. If the multiplying factors weigh in at say 10% the option is less straightforward and perhaps not something someone would want to do, as the surgeries are not without trauma and side effects. Its great to be optimistic and open minded, but not so open that your brains fall out. Nutritional  medicine and herbs have a place and Gerson diets, Budwig principle, http://www.budwigcenter.com/the-budwig-diet/#.VRT1nmeJhdg,  and essential oils can help and I encourage you all to review https://www.youtube.com/watch?v=LHKaVd_twIE
apple 415
The risk factors based on genetic testing may also be misleading.http://www.survive-and-thrive-cancer.com/angelinajoliemastectomy.aspx#.VTcdF5WlBFR It may well be that the risk of breast cancer being passed down through the generations is seldom due to true genetic inheritance but rather due to an ‘inheritance’ of similar non-constructive dietary habits, lifestyle ways and emotional patterns.
I advocate careful choices–>health, nutrigenomics, herbal medicine and Surgery if it is indicated. It does very little to support the patient to say that “they must have eaten too many toxins or didn’t take enough tumeric, or didn’t pray enough or eat enough salad” if they, in fact drew the short straw in the gene pool. As more of us become thoroughly educated about the genetic risk factors, we may be seeing a whole new method of cancer treatment- genetic manipulation and deletion of some of our nasty genes. There is already the possibility of adding the mitochondria from a third person into an embryo making a “three person zygote”. Hmmm, now that is an interesting concept. We likely will not achieve immortality, nor would we want that- where will everyone fit on the planet? 😉

So the point is the oncological checks for ovarian cancer are so far poor diagnostic and prognostic indicators , ultrasound does not diagnose (It can’t differentiate a benign cyst from malignancy) , the cancer markers are somewhat inaccurate (benign uterine fibroids also elevate CA125), and the genetic potential is the only marker that is relatively accurate in identifying risks. The diagnosis of ovarian cancer is best made by excising the suspect ovary- the complete ovary within a bag carefully, with no Fine Needle aspirate- it seeds the cells into the peritoneum. The surgery is tricky, but curative.   If you have been given a big bundle of bad genes its probably better out than in, but if you have only a minor “bad hand” you might want to think about it – rest and digest, but pay closer attention to monitoring. (Ultrasound and serum testing CA125 and HE4). Eat healthy take in daily antioxidants and antitumour diets.  Avoid processed meat (ham, salami) and eat a largely plant based, preferably organic diet.  Avoid simple sugars. Joanna Budwig diet of flax seed oil and cottage or quark cheese with your salads is likely beneficial.  See our facebook site for more!    https://www.facebook.com/Naturopathvet?fref=nf

Get your antioxidants in early in the day, and take large quantities!

Get your antioxidants early in the day, and take large quantities! Juice it up, but avoid simple sugars and choose green vegetables with each meal.  Ripe fruit provides enzymes for your body to digest. Have 1gm/kg body weight protein.