Vaccinology: for those that need to see the science

….here are 332 studies which show the other side of the issue.
To believe vaccination is 100 effective and that it does not have any major side effects is an absolute contortion of the scientific facts. To make vaccination mandatory takes away our freedom of choice and makes a mockery of informed consent. There is a humans rights issue involved here too with regards to mandatory vaccination.” – scroll down to see the studies:
Link Between Neurologic and Immune Disorders
Aluminum
Aluminum Vaccine Adjuvants: Are they Safe?
http://www.ncbi.nlm.nih.gov/pubmed/21568886
Mechanisms of aluminum adjuvant toxicity and autoimmunity in pediatric populations
http://lup.sagepub.com/content/21/2/223.short
Aluminum hydroxide injections lead to motor deficits and motor neuron degeneration
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819810/
Long-term Persistence of Vaccine-Derived Aluminum Hydroxide is Associated with Chronic Cognitive Dysfunction
http://www.sciencedirect.com/…/article/pii/S0162013409001895
Long-term follow-up of cognitive dysfunction in patients with aluminum hydroxide-induced macrophagic myofasciitis (MMF).
http://www.sciencedirect.com/…/article/pii/S0162013411002194
Do aluminum vaccine adjuvants contribute to the rising prevalence of autism?
http://www.ncbi.nlm.nih.gov/pubmed/22099159
Aluminum Adjuvant Linked to Gulf War Illness Induces Motor Neuron Death in Mice
http://www.springerlink.com/content/x457214811q62412/
The immunobiology of aluminium adjuvants: how do they really work?
http://www.sciencedirect.com/…/article/pii/S1471490609002488
Aluminum inclusion macrophagic myofasciitis: a recently identified condition
http://www.ncbi.nlm.nih.gov/pubmed/14753387
Macrophagic myofasciitis lesions assess long-term persistence of vaccine-derived aluminium hydroxide in muscle
http://brain.oxfordjournals.org/content/…/1821.full.pdf+html
A role for the body burden of aluminium in vaccine-associated macrophagic myofasciitis and chronic fatigue syndrome
http://www.medical-hypotheses.com/…/S0306-9877(08)…/abstract
Aluminum as an adjuvant in Crohn’s disease induction
http://lup.sagepub.com/content/21/2/231.abstract
Aluminum is a potential environmental factor for Crohn’s disease induction: extended hypothesis
http://www.ncbi.nlm.nih.gov/pubmed/17804561
DNA released from dying host cells mediates aluminum adjuvant activity
http://www.nature.com/nm/journal/v17/n8/full/nm.2403.html
Mercury
Sorting out the spinning of autism: heavy metals and the question of incidence
This file is a PDF http://www.ane.pl/pdf/7021.pdf
Comparison of blood and brain mercury levels in infant monkeys exposed to methylmercury or vaccines containing thimerosal
http://www.ncbi.nlm.nih.gov/pubmed/16079072
A Case Series of Children with Apparent Mercury Toxic Encephalopathies Manifesting with Clinical Symptoms of Regressive Autistic Disorders
http://www.ncbi.nlm.nih.gov/pubmed/17454560
Neurodevelopmental disorders following thimerosal-containing childhood immunizations: a follow-up analysis
http://www.ncbi.nlm.nih.gov/pubmed/15764492
Persistent behavioral impairments and alterations of brain dopamine system after early postnatal administration of thimerosal in rats
http://www.ncbi.nlm.nih.gov/pubmed/21549155
Maternal thimerosal exposure results in aberrant cerebellar oxidative stress, thyroid hormone metabolism, and motor behavior in rat pups; sex- and strain-dependent effects
http://www.ncbi.nlm.nih.gov/pubmed/22015705
Neonatal administration of thimerosal causes persistent changes in mu opioid receptors in the rat brain
http://www.ncbi.nlm.nih.gov/pubmed/20803069
Integrating experimental (in vitro and in vivo) neurotoxicity studies of low-dose thimerosal relevant to vaccines
http://www.ncbi.nlm.nih.gov/pubmed/21350943
Thimerosal-Derived Ethylmercury Is a Mitochondrial Toxin in Human Astrocytes: Possible Role of Fenton Chemistry in the Oxidation and Breakage of mtDNA
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395253/
Activation of methionine synthase by insulin-like growth factor-1 and dopamine: a target for neurodevelopmental toxins and thimerosal
http://www.ncbi.nlm.nih.gov/pubmed/14745455
Administration of thimerosal to infant rats increases overflow of glutamate and aspartate in the prefrontal cortex: protective role of dehydroepiandrosterone sulfate.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264864/
Neurologic and Immune Development
The Emerging Link Between Autoimmune Disorders and Neuropsychiatric Disease
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086677/
Influence of pediatric vaccines on amygdala growth and opioid ligand binding in rhesus macaque infants: A pilot study
This file is a PDF http://www.ane.pl/pdf/7020.pdf
Primary Immunization of Premature Infants with Gestational Age <35 Weeks: Cardiorespiratory Complications and C-Reactive Protein Responses Associated with Administration of Single and Multiple Separate Vaccines Simultaneously
http://www.jpeds.com/article/S0022-3476(07)00185-0/abstract
Neonatal administration of thimerosal causes persistent changes in mu opioid receptors in the rat brain
http://www.ncbi.nlm.nih.gov/pubmed/20803069
Maternal thimerosal exposure results in aberrant cerebellar oxidative stress, thyroid hormone metabolism, and motor behavior in rat pups; sex- and strain-dependent effects
http://www.ncbi.nlm.nih.gov/pubmed/22015705
Administration of thimerosal to infant rats increases overflow of glutamate and aspartate in the prefrontal cortex: protective role of dehydroepiandrosterone sulfate.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264864/
Molecular mechanisms underlying anti-inflammatory phenotype of neonatal splenic macrophages
http://www.jleukbio.org/content/82/2/403.full.pdf+html
Abnormal measles-mumps-rubella antibodies and CNS autoimmunity in children with autism
http://www.ncbi.nlm.nih.gov/pubmed/12145534
Integrating experimental (in vitro and in vivo) neurotoxicity studies of low-dose thimerosal relevant to vaccines
http://www.ncbi.nlm.nih.gov/pubmed/21350943
Serological association of measles virus and human herpesvirus-6 with brain autoantibodies in autism
http://www.ncbi.nlm.nih.gov/pubmed/9756729
In Harm’s Way: Toxic Threats to Child Development
http://action.psr.org/site/DocServer/frontmatter.pdf
Novel roles for immune molecules in neural development: implications for neurodevelopmental disorders (Many toxic insults discussed but not vaccines.)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059681/
Immune Activation in Brain Aging and Neurodegeneration: Too Much or Too Little?
http://www.sciencedirect.com/…/article/pii/S0896627309006771
Neurologic and Immune Dysfunction
Primary Immunization of Premature Infants with Gestational Age <35 Weeks: Cardiorespiratory Complications and C-Reactive Protein Responses Associated with Administration of Single and Multiple Separate Vaccines Simultaneously
http://www.jpeds.com/article/S0022-3476(07)00185-0/abstract
Neurodevelopmental disorders following thimerosal-containing childhood immunizations: a follow-up analysis
http://www.ncbi.nlm.nih.gov/pubmed/15764492
Persistent behavioral impairments and alterations of brain dopamine system after early postnatal administration of thimerosal in rats
http://www.ncbi.nlm.nih.gov/pubmed/21549155
Maternal thimerosal exposure results in aberrant cerebellar oxidative stress, thyroid hormone metabolism, and motor behavior in rat pups; sex- and strain-dependent effects
http://www.ncbi.nlm.nih.gov/pubmed/22015705
Administration of thimerosal to infant rats increases overflow of glutamate and aspartate in the prefrontal cortex: protective role of dehydroepiandrosterone sulfate
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264864/
A possible central mechanism in autism spectrum disorders, part 1
http://www.ncbi.nlm.nih.gov/pubmed/19043938
A possible central mechanism in autism spectrum disorders, part 2: immunoexcitotoxicity
http://www.ncbi.nlm.nih.gov/pubmed/19161050
A possible central mechanism in autism spectrum disorders, part 3: the role of excitotoxin food additives and the synergistic effects of other environmental toxins
http://www.ncbi.nlm.nih.gov/pubmed/19284184
Oily adjuvants and autoimmunity: now time for reconsideration?
http://lup.sagepub.com/content/21/2/217.abstract
Evidence of Mitochondrial Dysfunction in Autism and Implications for Treatment
This file is a PDF http://www.icdrc.org/documents/Mitoandautism2008.pdf
Fatal outcome after postexposure rabies vaccination in a patient with Parkinson’s disease
http://www.ncbi.nlm.nih.gov/pubmed/15675624
Specific Vaccines
Neurological Complications of Pertussis Immunization
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025848/?page=1
DPT Vaccine and Chronic Nervous System Dysfunction: A New Analysis
http://www.nap.edu/catalog.php?record_id=9814#toc
Abnormal measles-mumps-rubella antibodies and CNS autoimmunity in children with autism
http://www.ncbi.nlm.nih.gov/pubmed/12145534
Pertussis toxin is required for pertussis vaccine encephalopathy
This file is a PDF http://www.ncbi.nlm.nih.gov/…/PMC391…/pdf/pnas00364-0469.pdf
Hepatitis B triple series vaccine and developmental disability in US children aged 1-9 years
http://www.tandfonline.com/doi/abs/10.1080/02772240701806501
CNS demyelination and quadrivalent HPV vaccination
http://msj.sagepub.com/content/15/1/116.short
Increased Incidence and Clinical Picture of Childhood Narcolepsy following the 2009 H1N1 Pandemic Vaccination Campaign in Finland
http://www.plosone.org/…/info%3Adoi%2F10.1371%2Fjournal.pon…
Safety and immunogenicity of H5N1 vaccine
http://www.thelancet.com/…/PIIS0140-6736(06)69891-7/fulltext
Child influenza vaccination: Ramifications of adverse events in children in Australia
http://www.bmj.com/content/340/bmj.c2994
Progression of Renal Disease in Henoch-Schönlein Purpura After Influenza Vaccination
(Click PDF in upper right corner for full text)
http://jama.jamanetwork.com/article.aspx?articleid=367705
Henoch–Schönlein purpura following meningitis C vaccination
http://rheumatology.oxfordjournals.org/content/40/3/345.full
Fatal outcome after postexposure rabies vaccination in a patient with Parkinson’s disease
http://www.ncbi.nlm.nih.gov/pubmed/15675624
Brain Inflammation (encephalitis) Post Vaccination
Neurological Complications of Pertussis Immunization
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025848/?page=1
Acute disseminated encephalomyelitis
http://www.neurology.org/content/68/16_suppl_2/S23.abstract
Acute disseminated encephalomyelitis following influenza vaccination
Full text available by clicking PDF in upper right corner
http://archneur.jamanetwork.com/article.aspx
A Case Series of Children with Apparent Mercury Toxic Encephalopathies Manifesting with Clinical Symptoms of Regressive Autistic Disorders
http://www.ncbi.nlm.nih.gov/pubmed/17454560
Vaccination against Whooping-Cough: Efficacy versus Risks
http://www.sciencedirect.com/…/article/pii/S0140673677910285
DPT Vaccine and Chronic Nervous System Dysfunction: A New Analysis
http://www.nap.edu/catalog.php?record_id=9814#toc
Acute disseminated encephalomyelitis
http://pmj.bmj.com/content/79/927/11.full
Pertussis toxin is required for pertussis vaccine encephalopathy
This file is a PDF http://www.ncbi.nlm.nih.gov/…/PMC391…/pdf/pnas00364-0469.pdf
Acute necrotizing encephalopathy secondary to diphtheria, tetanus toxoid and whole-cell pertussis vaccination: diffusion-weighted imaging and proton MR spectroscopy findings
http://www.springerlink.com/content/44xt417387hx4877/
The smallpox vaccine and postvaccinal encephalitis
http://www.ncbi.nlm.nih.gov/pubmed/12170398
Encephalo-Myelitis following Vaccination
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2047920/
Encephalo-Myelitis following Vaccination
http://actx.beta.download.thelancet.com/…/PIIS0140…/fulltext
Subacute sclerosing panencephalitis–the continuing threat
Deaths Attributable to Smallpox Vaccination, 1959 to 1966, and 1968
Click PDF in upper right corner for full text.
http://jama.jamanetwork.com/article.aspx
Acute encephalopathy and chronic neurological damage after pertussis vaccine
http://www.ncbi.nlm.nih.gov/pubmed/7906066
Encephalopathies following prophylactic pertussis vaccine
http://pediatrics.aappublications.org/content/…/437.abstract
Treatment of lethal pertussis vaccine reaction with histamine H1 antagonists
http://www.neurology.org/content/37/6/1068
Murine model for pertussis vaccine encephalopathy: linkage to H-2
http://www.nature.com/…/journal/v299/n5885/abs/299738a0.html
Autoimmune Disease
‘ASIA’ – Autoimmune/Inflammatory Syndrome
‘ASIA’ – Autoimmune/Inflammatory Syndrome Induced by Adjuvants
http://www.ncbi.nlm.nih.gov/pubmed/20708902
The spectrum of ASIA: ‘Autoimmune (Auto-inflammatory) Syndrome induced by Adjuvants’
http://lup.sagepub.com/content/21/2/118.full.pdf+html
ASIA: A New Way to Put the Puzzle Together: Autoimmune (autoinflammatory) syndrome induced by adjuvants provides a diagnostic framework for enigmatic conditions
http://www.the-rheumatologist.org/…/ASIA_A_New_Way_to_Put_t…
Induction of the ‘ASIA’ syndrome in NZB/NZWF1 mice after injection of complete Freund’s adjuvant (CFA)
http://lup.sagepub.com/content/21/2/203.abstract
The common immunogenic etiology of chronic fatigue syndrome: from infections to vaccines via adjuvants to the ASIA syndrome
http://www.ncbi.nlm.nih.gov/pubmed/22054760
Shoenfeld’s Syndrome After Pandemic Influenza A/H1N1 Vaccination (Download free full text by clicking ACTA Reumatologica Portuguesa in upper right corner.)
http://www.ncbi.nlm.nih.gov/pubmed/21483283
Human Adjuvant Disease Induced by Foreign Substances: A New Model of ASIA
http://lup.sagepub.com/content/21/2/128.full.pdf+html
Gulf War Syndrome as a part of the autoimmune (autoinflammatory) syndrome induced by adjuvant (ASIA)
http://lup.sagepub.com/content/21/2/190.abstract
Adjuvant Immunization Induces High Levels of Pathogenic Antiphospholipid Antibodies in Genetically Prone Mice: Another Facet of the ASIA Syndrome
http://lup.sagepub.com/content/21/2/210.abstract
Autoimmunity Following Hepatitis B Vaccine as Part of the Spectrum of ‘Autoimmune (Auto-inflammatory) Syndrome Induced by Adjuvants’ (ASIA): analysis of 93 cases
http://lup.sagepub.com/content/21/2/146.abstract
Macrophagic Myofasciitis
Macrophagic myofasciitis lesions assess long-term persistence of vaccine-derived aluminium hydroxide in muscle
http://brain.oxfordjournals.org/content/…/1821.full.pdf+html
Macrophagic myofasciitis: characterization and pathophysiology
http://lup.sagepub.com/content/21/2/184.abstract
Lessons From Macrophagic Myofasciitis: Towards Definition of a Vaccine Adjuvant-Related Syndrome
http://www.ncbi.nlm.nih.gov/pubmed/12660567
AlOH3-adjuvanted vaccine-induced macrophagic myofasciitis in rats is influenced by the genetic background
http://www.ncbi.nlm.nih.gov/pubmed/16616846
Multiple Sclerosis and Demyelinating Disease
Recombinant Hepatitis B Vaccine and the Risk of Multiple Sclerosis: a Prospective Study
http://www.ncbi.nlm.nih.gov/pubmed/15365133
CNS Demyelination and Quadrivalent HPV Vaccination
http://msj.sagepub.com/content/15/1/116.short
Asthma and Allergy
Is infant immunization a risk factor for childhood asthma or allergy?
http://www.ncbi.nlm.nih.gov/pubmed/9345669
Infection of Human B Lymphocytes with MMR Vaccine Induces IgE Class Switching
http://www.ncbi.nlm.nih.gov/pubmed/11513549
Delay in diphtheria, pertussis, tetanus vaccination is associated with a reduced risk of childhood asthma
http://www.jacionline.org/ar…/S0091-6749(07)02379-2/fulltext
Effects of diphtheria-tetanus-pertussis or tetanus vaccination on allergies and allergy-related respiratory symptoms among children and adolescents in the United States
http://www.ncbi.nlm.nih.gov/pubmed/10714532
Vaccination and Allergic Disease: A Birth Cohort Study
(Interesting to note that the data show a risk of allergic disease after vaccination but the authors dismiss it in their conclusion.)
http://ajph.aphapublications.org/…/pdf/10.2105/AJPH.94.6.985
The relationship between vaccine refusal and self-report of atopic disease in children
http://www.sciencedirect.com/…/article/pii/S0091674905000266
Rheumatic Disease
Immunization of patients with autoimmune inflammatory rheumatic diseases (the EULAR recommendations)
http://lup.sagepub.com/content/21/2/162.abstract
Chronic Arthritis after Rubella Vaccination
http://cid.oxfordjournals.org/content/15/2/307.short
Autoimmune response following influenza vaccination in patients with autoimmune inflammatory rheumatic disease
http://lup.sagepub.com/content/21/2/175.abstract
Giant cell arteritis and polymyalgia rheumatica after influenza vaccination: report of 10 cases and review of the literature
http://lup.sagepub.com/content/21/2/153.abstract
Diabetes
Pertussis infections, vaccines and Type 1 diabetes
http://onlinelibrary.wiley.com/…/j.1464-5491.2004.0114…/full
Clustering of cases of type 1 diabetes mellitus occurring 2-4 years after vaccination is consistent with clustering after infections and progression to type 1 diabetes mellitus in autoantibody positive individuals
http://www.ncbi.nlm.nih.gov/pubmed/12793601
Clustering of cases of insulin dependent diabetes (IDDM) occurring three years after hemophilus influenza B (HiB) immunization support causal relationship between immunization and IDDM
http://www.ncbi.nlm.nih.gov/pubmed/12482192
Vaccines and the risk of insulin-dependent diabetes (IDDM): potential mechanism of action
http://www.medical-hypotheses.com/…/S0306-9877(01)…/abstract
Italian pediatric data support hypothesis that simultaneous epidemics of type 1 diabetes and type 2 diabetes/metabolic syndrome/obesity are polar opposite responses (i.e., symptoms) to a primary inflammatory condition
http://www.degruyter.com/…/…/jpem.2011.023/jpem.2011.023.xml
Specific Vaccines and Autoimmunity
Abnormal measles-mumps-rubella antibodies and CNS autoimmunity in children with autism
http://www.ncbi.nlm.nih.gov/pubmed/12145534
Autoimmune hazards of hepatitis B vaccine
http://www.sciencedirect.com/…/article/pii/S1568997204002010
Vaccine Model of Antiphospholipid Syndrome Induced by Tetanus Vaccine
http://lup.sagepub.com/content/21/2/195.abstract
Influenza vaccination can induce new-onset anticardiolipins but not ß2-glycoprotein-I antibodies among patients with systemic lupus erythematosus
http://lup.sagepub.com/content/21/2/168.abstract
Influenza and autoimmunity
http://onlinelibrary.wiley.com/…/j.1749-6632.2009.…/abstract
Systemic lupus erythematosus following HPV immunization or infection?
http://lup.sagepub.com/content/21/2/158.abstract
Early diphtheria-tetanus-pertussis vaccination associated with higher female mortality and no difference in male mortality in a cohort of low birthweight children: an observational study within a randomised trial
http://adc.bmj.com/…/20…/02/13/archdischild-2011-300646.full
Effects of diphtheria-tetanus-pertussis or tetanus vaccination on allergies and allergy-related respiratory symptoms among children and adolescents in the United States
http://www.ncbi.nlm.nih.gov/pubmed/10714532
Henoch–Schönlein purpura following meningitis C vaccination
http://rheumatology.oxfordjournals.org/content/40/3/345.full
Other Autoimmune Diseases
Characterization of antigen-presenting dendritic cells in the peripheral blood and colonic mucosa of patients with ulcerative colitis
http://www.ncbi.nlm.nih.gov/pubmed/11474315
Polymerase chain reaction detection of the hemagglutinin gene from an attenuated measles vaccine strain in the peripheral mononuclear cells of children with autoimmune hepatitis
http://www.springerlink.com/content/tln20u18374r4q30/
Early Childhood Membranous Nephropathy Due to Cationic Bovine Serum Albumin (Though not mentioned by the authors, Bovine Serum is in vaccines.)
http://www.nejm.org/doi/full/10.1056/NEJMoa1013792
The common immunogenic etiology of chronic fatigue syndrome: from infections to vaccines via adjuvants to the ASIA syndrome
http://www.ncbi.nlm.nih.gov/pubmed/22054760
General Autoimmunity Issues
Vaccines and autoimmunity
http://www.nature.com/…/jo…/v5/n11/abs/nrrheum.2009.196.html
Vaccine-induced Autoimmunity
http://www.sciencedirect.com/…/article/pii/S0896841196900918
Mechanisms of aluminum adjuvant toxicity and autoimmunity in pediatric populations
http://lup.sagepub.com/content/21/2/223.short
The Emerging Link Between Autoimmune Disorders and Neuropsychiatric Disease
This file is a PDF http://www.ncbi.nlm.nih.gov/…/PMC3086677/pdf/nihms284704.pdf
Serological association of measles virus and human herpesvirus-6 with brain autoantibodies in autism
http://www.ncbi.nlm.nih.gov/pubmed/9756729
Adjuvant Immunization Induces High Levels of Pathogenic Antiphospholipid Antibodies in Genetically Prone Mice: Another Facet of the ASIA Syndrome
http://lup.sagepub.com/content/21/2/210.abstract
Self-Organized Criticality Theory of Autoimmunity
http://www.plosone.org/…/info%3Adoi%2F10.1371%2Fjournal.pon…
Gut-Brain-Immune System Connection and Function Development
Autism: an emerging ‘neuroimmune disorder’ in search of therapy
http://informahealthcare.com/…/abs/10.1517/14656560903107789
Normal gut microbiota modulates brain development and behavior
http://www.pnas.org/content/108/7/3047.full
Novel roles for immune molecules in neural development: implications for neurodevelopmental disorders
(Many toxic insults discussed but not vaccines.)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059681/
Immune Proteins in Brain Development and Synaptic Plasticity
http://www.sciencedirect.com/…/article/pii/S0896627309006783
Function
Gastrointestinal Pathology in Autism Spectrum Disorders: The Venezuelan Experience
http://www.scribd.com/…/Gastrointestinal-Pathology-in-Autis…
Clinical Presentation and Histologic Findings at Ileocolonoscopy in Children with Autistic Spectrum Disorder and Chronic Gastrointestinal Symptoms
(Click “Download Paper” for full text)
http://www.la-press.com/clinical-presentation-and-histologi
Characterization of antigen-presenting dendritic cells in the peripheral blood and colonic mucosa of patients with ulcerative colitis
http://www.ncbi.nlm.nih.gov/pubmed/11474315
A possible central mechanism in autism spectrum disorders, part 1
http://www.ncbi.nlm.nih.gov/pubmed/19043938
A possible central mechanism in autism spectrum disorders, part 2: immunoexcitotoxicity
http://www.ncbi.nlm.nih.gov/pubmed/19161050
A possible central mechanism in autism spectrum disorders, part 3: the role of excitotoxin food additives and the synergistic effects of other environmental toxins
http://www.ncbi.nlm.nih.gov/pubmed/19284184
Efficacy of methylcobalamin and folinic acid treatment on glutathione redox status in children with autism
http://www.ajcn.org/content/89/1/425.long
Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2610366/
Oxidative stress-related biomarkers in autism: Systematic review and meta-analyses
http://www.sciencedirect.com/…/article/pii/S0891584912001827
Immune-glutamatergic dysfunction as a central mechanism of the autism spectrum disorders
http://www.benthamdirect.org/pages/content.php
Central and Peripheral Cytokines Mediate Immune-Brain Connectivity
http://www.springerlink.com/content/f6718rl3g2k75656/
No Antibodies Required For Immunity Against Some Viruses: B Cell Maintenance of Subcapsular Sinus Macrophages Protects against a Fatal Viral Infection Independent of Adaptive Immunity
http://www.cell.com/immunity/abstract/S1074-7613(12)00057-X
Immune Activation in Brain Aging and Neurodegeneration: Too Much or Too Little?
http://www.sciencedirect.com/…/article/pii/S0896627309006771
Connection
Autism: an emerging ‘neuroimmune disorder’ in search of therapy
http://informahealthcare.com/…/abs/10.1517/14656560903107789
Molecular mechanisms underlying anti-inflammatory phenotype of neonatal splenic macrophages
http://www.jleukbio.org/content/82/2/403.full.pdf+html
Central and Peripheral Cytokines Mediate Immune-Brain Connectivity
http://www.springerlink.com/content/f6718rl3g2k75656/
Children with autism spectrum disorders (ASD) who exhibit chronic gastrointestinal (GI) symptoms and marked fluctuation of behavioral symptoms exhibit distinct innate immune abnormalities and transcriptional profiles of peripheral blood (PB) monocytes
http://www.jni-journal.com/a…/S0165-5728(11)00191-3/abstract
Panenteric IBD-Like Disease in a Patient with Regressive Autism Shown for the First Time by the Wireless Capsule Enteroscopy: Another Piece in the Jigsaw of this Gut-Brain Syndrome?
http://www.nature.com/…/journ…/v100/n4/full/ajg2005166a.html
Clinical Presentation and Histologic Findings at Ileocolonoscopy in Children with Autistic Spectrum Disorder and Chronic Gastrointestinal Symptoms
(Click “Download Paper” for full text)
http://www.la-press.com/clinical-presentation-and-histologi
Effectiveness of the gluten-free, casein-free diet for children diagnosed with autism spectrum disorder:
(Based on parental report)
http://www.ncbi.nlm.nih.gov/pubmed/22564339
Hypothesis: Conjugate vaccines may predispose children to autism spectrum disorders
http://www.sciencedirect.com/…/article/pii/S0306987711004117
A possible central mechanism in autism spectrum disorders, part 1
http://www.ncbi.nlm.nih.gov/pubmed/19043938
A possible central mechanism in autism spectrum disorders, part 2: immunoexcitotoxicity
http://www.ncbi.nlm.nih.gov/pubmed/19161050
A possible central mechanism in autism spectrum disorders, part 3: the role of excitotoxin food additives and the synergistic effects of other environmental toxins
http://www.ncbi.nlm.nih.gov/pubmed/19284184
Immune-glutamatergic dysfunction as a central mechanism of the autism spectrum disorders
http://www.benthamdirect.org/pages/content.php
Immune Activation in Brain Aging and Neurodegeneration: Too Much or Too Little?
http://www.sciencedirect.com/…/article/pii/S0896627309006771
Autism
Metals and Environmental Toxins in Autism
Sorting out the spinning of autism: heavy metals and the question of incidence
This file is a PDF http://www.ane.pl/pdf/7021.pdf
Neurodevelopmental disorders following thimerosal-containing childhood immunizations: a follow-up analysis
http://www.ncbi.nlm.nih.gov/pubmed/15764492
A Case Series of Children with Apparent Mercury Toxic Encephalopathies Manifesting with Clinical Symptoms of Regressive Autistic Disorders
http://www.ncbi.nlm.nih.gov/pubmed/17454560
Persistent behavioral impairments and alterations of brain dopamine system after early postnatal administration of thimerosal in rats
http://www.ncbi.nlm.nih.gov/pubmed/21549155
Neonatal administration of thimerosal causes persistent changes in mu opioid receptors in the rat brain
http://www.ncbi.nlm.nih.gov/pubmed/20803069
Do aluminum vaccine adjuvants contribute to the rising prevalence of autism?
This file is a PDF http://omsj.org/reports/tomljenovic%202011.pdf
Administration of thimerosal to infant rats increases overflow of glutamate and aspartate in the prefrontal cortex: protective role of dehydroepiandrosterone sulfate
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264864/
Mercury in first-cut baby hair of children with autism versus typically-developing children
http://www.tandfonline.com/d…/abs/10.1080/02772240701699294…
Mercury induces inflammatory mediator release from human mast cells
http://www.biomedcentral.com/1742-2094/7/20
Maternal thimerosal exposure results in aberrant cerebellar oxidative stress, thyroid hormone metabolism, and motor behavior in rat pups; sex- and strain-dependent effects
http://www.ncbi.nlm.nih.gov/pubmed/22015705
How environmental and genetic factors combine to cause autism: A redox/methylation hypothesis
http://www.sciencedirect.com/…/article/pii/S0161813X0700215X
Comparison of blood and brain mercury levels in infant monkeys exposed to methylmercury or vaccines containing thimerosal
http://www.ncbi.nlm.nih.gov/pubmed/16079072
Integrating experimental (in vitro and in vivo) neurotoxicity studies of low-dose thimerosal relevant to vaccines
http://www.ncbi.nlm.nih.gov/pubmed/21350943
Thimerosal-Derived Ethylmercury Is a Mitochondrial Toxin in Human Astrocytes: Possible Role of Fenton Chemistry in the Oxidation and Breakage of mtDNA
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395253/
Neuroimmune Disorders in Autism
Influence of pediatric vaccines on amygdala growth and opioid ligand binding in rhesus macaque infants: A pilot study
This file is a PDF http://www.ane.pl/pdf/7020.pdf
Persistent behavioral impairments and alterations of brain dopamine system after early postnatal administration of thimerosal in rats
http://www.ncbi.nlm.nih.gov/pubmed/21549155
Neurodevelopmental disorders following thimerosal-containing childhood immunizations: a follow-up analysis
http://www.ncbi.nlm.nih.gov/pubmed/15764492
Neonatal administration of thimerosal causes persistent changes in mu opioid receptors in the rat brain
http://www.ncbi.nlm.nih.gov/pubmed/20803069
Abnormal measles-mumps-rubella antibodies and CNS autoimmunity in children with autism
http://www.ncbi.nlm.nih.gov/pubmed/12145534
Maternal thimerosal exposure results in aberrant cerebellar oxidative stress, thyroid hormone metabolism, and motor behavior in rat pups; sex- and strain-dependent effects
http://www.ncbi.nlm.nih.gov/pubmed/22015705
Serological association of measles virus and human herpesvirus-6 with brain autoantibodies in autism
http://www.ncbi.nlm.nih.gov/pubmed/9756729
Autism: an emerging ‘neuroimmune disorder’ in search of therapy
http://informahealthcare.com/…/abs/10.1517/14656560903107789
Administration of thimerosal to infant rats increases overflow of glutamate and aspartate in the prefrontal cortex: protective role of dehydroepiandrosterone sulfate.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264864/
A possible central mechanism in autism spectrum disorders, part 1
http://www.ncbi.nlm.nih.gov/pubmed/19043938
A possible central mechanism in autism spectrum disorders, part 2: immunoexcitotoxicity
http://www.ncbi.nlm.nih.gov/pubmed/19161050
A possible central mechanism in autism spectrum disorders, part 3: the role of excitotoxin food additives and the synergistic effects of other environmental toxins
http://www.ncbi.nlm.nih.gov/pubmed/19284184
Evidence of Mitochondrial Dysfunction in Autism and Implications for Treatment
This file is a PDF http://www.icdrc.org/documents/Mitoandautism2008.pdf
Neuroglial activation and neuroinflammation in the brain of patients with autism
http://www.ncbi.nlm.nih.gov/pubmed/15546155
Thimerosal-Derived Ethylmercury Is a Mitochondrial Toxin in Human Astrocytes: Possible Role of Fenton Chemistry in the Oxidation and Breakage of mtDNA
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395253/
Environment and Genetics in Autism
Genetic Heritability and Shared Environmental Factors Among Twin Pairs With Autism
http://archpsyc.jamanetwork.com/article.aspx
How environmental and genetic factors combine to cause autism: A redox/methylation hypothesis
http://www.sciencedirect.com/…/article/pii/S0161813X0700215X
Theoretical aspects of autism: Causes—A review
http://informahealthcare.com/…/abs/10.…/1547691X.2010.545086
Gastrointestinal Disease in Autism
Children with autism spectrum disorders (ASD) who exhibit chronic gastrointestinal (GI) symptoms and marked fluctuation of behavioral symptoms exhibit distinct innate immune abnormalities and transcriptional profiles of peripheral blood (PB) monocytes
http://www.jni-journal.com/a…/S0165-5728(11)00191-3/abstract
Panenteric IBD-Like Disease in a Patient with Regressive Autism Shown for the First Time by the Wireless Capsule Enteroscopy: Another Piece in the Jigsaw of this Gut-Brain Syndrome?
http://www.nature.com/…/journ…/v100/n4/full/ajg2005166a.html
Clinical Presentation and Histologic Findings at Ileocolonoscopy in Children with Autistic Spectrum Disorder and Chronic Gastrointestinal Symptoms
(Click “Download Paper” for full text)
http://www.la-press.com/clinical-presentation-and-histologi
Gastrointestinal Pathology in Autism Spectrum Disorders: The Venezuelan Experience
http://www.scribd.com/…/Gastrointestinal-Pathology-in-Autis…
Autistic enterocolitis: Fact or fiction?
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694587/
Autistic Enterocolitis: Confirmation of a New Inflammatory Bowel Disease in An Italian Cohort of Patients
http://www.latitudes.org/forums/index.php?showtopic=1409
Specific Vaccines and Autism
Abnormal measles-mumps-rubella antibodies and CNS autoimmunity in children with autism
http://www.ncbi.nlm.nih.gov/pubmed/12145534
Hypothesis: Conjugate vaccines may predispose children to autism spectrum disorders
http://www.sciencedirect.com/…/article/pii/S0306987711004117
Hepatitis B Vaccination of Male Neonates and Autism, NHIS 1997–2002
http://www.tandfonline.com/…/p…/10.1080/15287394.2010.519317
Elevated levels of measles antibodies in children with autism
http://www.sciencedirect.com/…/article/pii/S0887899402006276
Methylation in Autism
Efficacy of methylcobalamin and folinic acid treatment on glutathione redox status in children with autism
http://www.ajcn.org/content/89/1/425.long
Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2610366/
Oxidative stress-related biomarkers in autism: Systematic review and meta-analyses
http://www.sciencedirect.com/…/article/pii/S0891584912001827
How environmental and genetic factors combine to cause autism: A redox/methylation hypothesis
http://www.sciencedirect.com/…/article/pii/S0161813X0700215X
Thimerosal-Derived Ethylmercury Is a Mitochondrial Toxin in Human Astrocytes: Possible Role of Fenton Chemistry in the Oxidation and Breakage of mtDNA
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395253/
Unexplained Infant Death
Infant mortality rates regressed against number of vaccine doses routinely given: is there a biochemical or synergistic toxicity?
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170075/
Primary Immunization of Premature Infants with Gestational Age <35 Weeks: cardiorespiratory Complications and C-Reactive Protein Responses Associated with Administration of Single and Multiple Separate Vaccines Simultaneously
http://www.jpeds.com/article/S0022-3476(07)00185-0/abstract
Unexplained cases of sudden infant death shortly after hexavalent vaccination
http://www.sciencedirect.com/…/article/pii/S0264410X05004688
Unexplained cases of sudden infant death shortly after hexavalent vaccination – rebuttal
http://www.murciasalud.es/archivo.php?id=88521
Simultaneous sudden infant death syndrome
http://www.ncbi.nlm.nih.gov/pubmed/17654772
Treatment of lethal pertussis vaccine reaction with histamine H1 antagonists.
http://www.neurology.org/content/37/6/1068
Murine model for pertussis vaccine encephalopathy: linkage to H-2.
http://www.nature.com/…/journal/v299/n5885/abs/299738a0.html
Chronic Illness
Emergent Human Pathogen Simian Virus 40 and Its Role in Cancer
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC452549/
‘ASIA’ – autoimmune/inflammatory syndrome induced by adjuvants
http://www.ncbi.nlm.nih.gov/pubmed/20708902
The common immunogenic etiology of chronic fatigue syndrome: from infections to vaccines via adjuvants to the ASIA syndrome
http://www.ncbi.nlm.nih.gov/pubmed/22054760
Aluminum as an adjuvant in Crohn’s disease induction
http://lup.sagepub.com/content/21/2/231.abstract
Aluminum is a potential environmental factor for Crohn’s disease induction: extended hypothesis
http://www.ncbi.nlm.nih.gov/pubmed/17804561
Characterization of antigen-presenting dendritic cells in the peripheral blood and colonic mucosa of patients with ulcerative colitis
http://www.ncbi.nlm.nih.gov/pubmed/11474315
The relationship between vaccine refusal and self-report of atopic disease in children
http://www.sciencedirect.com/…/article/pii/S0091674905000266
Antibodies to Saccharomyces cerevisiae in Crohn’s disease: Higher titers are associated with a greater frequency of mutant NOD2/CARD15 alleles and with a higher probability of complicated disease
http://onlinelibrary.wiley.com/doi/10.1002/ibd.20031/full
This item pairs with the link just above: The antigen is harvested and purified from fermentation cultures of a recombinant strain of the yeast Saccharomyces cerevisiae
This file is a PDF http://www.merck.com/…/pi…/r/recombivax_hb/recombivax_pi.pdf
Thimerosal-Derived Ethylmercury Is a Mitochondrial Toxin in Human Astrocytes: Possible Role of Fenton Chemistry in the Oxidation and Breakage of mtDNA
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395253/
Viral Infection and Neurologic Dysfunction
Antibodies to measles in individuals with recent onset psychosis
http://www.schres-journal.com/…/S0920-9964(09)0060…/abstract
Elevated levels of measles antibodies in children with autism
http://www.pedneur.com/artic…/S0887-8994(02)00627-6/abstract
The human endogenous retrovirus link between genes and environment in multiple sclerosis and in multifactorial diseases associating neuroinflammation
http://www.ncbi.nlm.nih.gov/pubmed/19697163
Endogenous retroviral genes, Herpesviruses and gender in Multiple Sclerosis
http://www.ncbi.nlm.nih.gov/pubmed/19447411
Endogenous retrovirus type W GAG and envelope protein antigenemia in serum of schizophrenic patients
http://www.ncbi.nlm.nih.gov/pubmed/18760403
The multiple sclerosis-associated retrovirus and its HERV-W endogenous family: a biological interface between virology, genetics, and immunology in human physiology and disease
http://www.ncbi.nlm.nih.gov/pubmed/19039700
Infection and Autoimmunity
http://wwwnc.cdc.gov/eid/article/12/3/05-1409_article.htm
The common immunogenic etiology of chronic fatigue syndrome: from infections to vaccines via adjuvants to the ASIA syndrome
http://www.ncbi.nlm.nih.gov/pubmed/22054760
Influenza and autoimmunity
http://onlinelibrary.wiley.com/…/j.1749-6632.2009.…/abstract
Subacute sclerosing panencephalitis–the continuing threat
(cut and paste link to download PDF)
hrcak.srce.hr/file/43654
Other Complications Post Vaccination
Emergent Human Pathogen Simian Virus 40 and Its Role in Cancer
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC452549/
Adverse Events following 12 and 18 Month Vaccinations: a Population-Based, Self-Controlled Case Series Analysis
http://www.plosone.org/…/info%3Adoi%2F10.1371%2Fjournal.pon…
Increased Incidence and Clinical Picture of Childhood Narcolepsy following the 2009 H1N1 Pandemic Vaccination Campaign in Finland
http://www.plosone.org/…/info%3Adoi%2F10.1371%2Fjournal.pon…
Henoch–Schönlein purpura following meningitis C vaccination
http://rheumatology.oxfordjournals.org/content/40/3/345.full
Fatal outcome after postexposure rabies vaccination in a patient with Parkinson’s disease
http://www.ncbi.nlm.nih.gov/pubmed/15675624
Discolored Leg Syndrome Following Vaccines:
http://www.ncbi.nlm.nih.gov/pubmed/18546020
Adverse Effects of Vaccines: Evidence and Causality
(From the text: The committee finds that evidence convincingly supports a causal relationship between some vaccines and some adverse events…evidence favors rejection of five vaccine-adverse event relationships… However, for the majority of cases (135 vaccine-adverse event pairs), the evidence was inadequate to accept or reject a causal relationship.”
http://www.iom.edu/…/Adverse-Effects-of-Vaccines-Evidence-a…
Vaccination Efficacy, Failure, and Disease Transmission
Disease Transmission
Attenuated vaccines can recombine to form virulent field viruses
http://www.sciencemag.org/content/337/6091/188.abstract
Sibling Transmission of Vaccine-Derived Rotavirus (RotaTeq) Associated With Rotavirus Gastroenteritis
This file is a PDF http://pediatrics.aappublications.org/…/peds.2009-1901.full…
The Evolutionary Consequences of Blood-Stage Vaccination on the Rodent Malaria Plasmodium chabaudi
http://www.plosbiology.org/…/info%3Adoi%2F10.1371%2Fjournal…(Ambra+-+Biology+New+Articles
Vaccine-acquired Rotavirus Infection in Two Infants with Severe Combined Immunodeficiency
http://www.jacionline.org/ar…/S0091-6749(09)00151-1/fulltext
Long-Term Circulation of Vaccine-Derived Poliovirus That Causes Paralytic Disease
http://jvi.asm.org/content/76/13/6791.full
Molecular and Antigenic Characterization of a Highly Evolved Derivative of the Type 2 Oral Poliovaccine Strain Isolated from Sewage in Israel
http://jcm.asm.org/content/38/10/3729.full
Prevalence of vaccine-derived polioviruses in the environment
http://jgv.sgmjournals.org/content/83/5/1107.full
Transmission of mumps virus from mumps-vaccinated individuals to close contact
http://www.ncbi.nlm.nih.gov/pubmed/21983359
Adventitious Agents and Vaccines
http://www.ncbi.nlm.nih.gov/…/a…/PMC2631857/pdf/11485673.pdf
Efficacy Issues/Failure
Why Do Pertussis (Whooping Couvh) Vaccines Fail?
http://pediatrics.aappublications.org/conte…/…/5/968.extract
Unexpectedly limited durability of immunity following acellular pertussis vaccination in preadolescents in a North American outbreak
http://cid.oxfordjournals.org/content/54/12/1730.abstract
Selection of Hepatitis B Virus (HBV) Vaccine Escape Mutants in HBV-Infected and HBV/HIV-Coinfected Patients Failing Antiretroviral Drugs With Anti-HBV Activity
http://journals.lww.com/…/Selection_of_Hepatitis_B_Virus__H…
Measles outbreak in a fully immunized secondary-school population
http://www.ncbi.nlm.nih.gov/pubmed/3821823
Acellular pertussis vaccination facilitates Bordetella parapertussis infection in a rodent model of bordetellosis.
http://www.ncbi.nlm.nih.gov/pubmed/20200027
Mumps outbreak among vaccinated university students associated with a large party, the Netherlands, 2010
http://www.sciencedirect.com/…/article/pii/S0264410X12006299
Waning Protection after Fifth Dose of Acellular Pertussis Vaccine in Children
http://www.nejm.org/doi/full/10.1056/NEJMoa1200850
Review of the United States universal varicella vaccination program: Herpes zoster incidence rates, cost-effectiveness, and vaccine efficacy based
primarily on the Antelope Valley Varicella Active Surveillance Project data
http://www.sciencedirect.com/…/article/pii/S0264410X12007761
Effectiveness of Jeryl Lynn-containing vaccine in Spanish children
http://www.ncbi.nlm.nih.gov/pubmed/19356610
Mumps Orchitis in the Post-Vaccine Era (1967Y2009)
This file is a PDF http://www.vaccine-tlc.org/docs/Mumps.pdf
Considerations for Viral Disease Eradication: Lessons Learned and Future Strategies
Quote: Important and often overlooked, mass vaccinations itself can also exert tremendous selective pressures and lead to the evolution of new infectious agents.
http://books.nap.edu/openbook.php?record_id=10424&page=R1
Recent Resurgence of Mumps in the United States
http://www.nejm.org/doi/full/10.1056/NEJMoa0706589#t=article
Risk of vaccine failure after Haemophilus influenzae type b (Hib) combination vaccines with acellular pertussis
http://www.thelancet.com/…/PIIS0140-6736(03)13171-6/fulltext
Subacute sclerosing panencephalitis–the continuing threat
(cut and paste link to download PDF)
http://www.hrcak.srce.hr/file/43654
Questionable Science and Policy
Placebos
What’s in Placebos: Who Knows? Analysis of Randomized, Controlled Trials
http://www.ncbi.nlm.nih.gov/pubmed/20956710
Testing vaccines in pediatric research subjects
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831649/
Policy
Adverse Effects of Vaccines: Evidence and Causality
(From the text: The committee finds that evidence convincingly supports a causal relationship between some vaccines and some adverse events…evidence favors rejection of five vaccine-adverse event relationships… However, for the majority of cases (135 vaccine-adverse event pairs), the evidence was inadequate to accept or reject a causal relationship.”
http://www.iom.edu/…/Adverse-Effects-of-Vaccines-Evidence-a…
Human papillomavirus (HPV) vaccine policy and evidence-based medicine: Are they at odds?
http://informahealthcare.com/…/abs/10.…/07853890.2011.645353
The Number Needed to Vaccinate to Prevent Infant Pertussis Hospitalization and Death Through Parent Cocoon Immunization
http://cid.oxfordjournals.org/…/…/12/01/cid.cir836.abstract…
The Evolutionary Consequences of Blood-Stage Vaccination on the Rodent Malaria Plasmodium chabaudi
http://www.plosbiology.org/…/info%3Adoi%2F10.1371%2Fjournal…(Ambra+-+Biology+New+Articles
Selection of Hepatitis B Virus (HBV) Vaccine Escape Mutants in HBV-Infected and HBV/HIV-Coinfected Patients Failing Antiretroviral Drugs With Anti-HBV Activity
http://journals.lww.com/…/Selection_of_Hepatitis_B_Virus__H…
Influenza Vaccination During Pregnancy: A Critical Assessment of the Recommendations of the Advisory Committee on Immunization Practices (ACIP)
http://www.jpands.org/vol11no2/ayoub.pdf
Review of the United States universal varicella vaccination program: Herpes zoster incidence rates, cost-effectiveness, and vaccine efficacy based primarily on the Antelope Valley Varicella Active Surveillance Project data http://www.sciencedirect.com/…/article/pii/S0264410X12007761
Adverse events and quadrivalent human papillomavirus recombinant vaccine
http://jama.jamanetwork.com/article.aspx
Attenuated vaccines can recombine to form virulent field viruses
http://www.sciencemag.org/content/337/6091/188.abstract
Mandatory HPV Vaccination
http://jama.jamanetwork.com/article.aspx?articleid=1104867
Acellular pertussis vaccination facilitates Bordetella parapertussis infection in a rodent model of bordetellosis.
http://www.ncbi.nlm.nih.gov/pubmed/20200027
No autoimmune safety signal after vaccination with quadrivalent HPV vaccine Gardasil?
http://tinyurl.com/72uvrb2
Influenza vaccination: policy versus evidence
http://www.bmj.com/content/333/7574/912%2523TBL2.full
Human papillomavirus vaccine trials in India
http://www.thelancet.com/…/PIIS0140-6736(11)60270-5/fulltext
Australia suspends seasonal flu vaccination of young children
http://www.bmj.com/content/340/bmj.c2419
Australia suspends seasonal flu vaccination of young children
http://www.bmj.com/…/adverse-events-following-influenza-vac…
Child influenza vaccination: Ramifications of adverse events in children in Australia
http://www.bmj.com/content/340/bmj.c2994
Vaccine safety: current systems and recent findings
http://journals.lww.com/…/Vaccine_safety__current_systems_a…
Excess mortality from seasonal influenza is negligible below the age of 50 in Israel: implications for vaccine policy
http://www.springerlink.com/content/2p44p50005827585/
Adventitious Agents and Vaccines
http://www.ncbi.nlm.nih.gov/…/a…/PMC2631857/pdf/11485673.pdf
Why Do Pertussis Vaccines Fail?
http://pediatrics.aappublications.org/conte…/…/5/968.extract
Vaccine Contamination
Mercury in vaccines from the Australian childhood immunization program schedule
http://www.ncbi.nlm.nih.gov/pubmed/20391108
Quantitation of DNA and Protein Impurities in Biopharmaceuticals -Liver Cancer?
http://pubs.acs.org/doi/abs/10.1021/ac00009a003
Cloned Hepatitis B Virus DNA causes hepatitis in chimpanzees
This file is a PDF http://www.nature.com/natu…/journal/…/n5885/pdf/299740a0.pdf
The Dangerous Impurities of Vaccines
http://www.scribd.com/patro…/d/49973741-Dangerous-Impurities
Adventitious Agents and Vaccines
http://www.ncbi.nlm.nih.gov/…/a…/PMC2631857/pdf/11485673.pdf
Veterinary Research
Attenuated vaccines can recombine to form virulent field viruses
http://www.sciencemag.org/content/337/6091/188.abstract
Vaccine-associated acute polyneuropathy resembling Guillain-Barré syndrome in a dog
http://www.mendeley.com/…/vaccineassociated-acute-polyneur…/
Viral status and antibody response in cattle inoculated with recombinant bovine leukemia virus-vaccinia virus vaccines after challenge exposure with bovine leukemia virus-infected lymphocytes
http://www.ncbi.nlm.nih.gov/pubmed/8725805
Interesting Articles, etc.
Vaccines for Children Program: Vulnerabilities in Vaccine Management
http://oig.hhs.gov/oei/reports/oei-04-10-00430.pdf
Guide to Vaccine Contraindications and Precautions – CDC
http://www.cdc.gov/…/downlo…/contraindications-guide-508.pdf
Charts Comparing Dead Babies to Vaccine Timeline:
http://therefusers.com/…/dead-babies-and-stillbirths-repor…/
Unvaccinated Children Are Healthier
This file is a PDF http://www.vaccineinjury.info/imag…/stories/ias1992study.pdf
State of health of unvaccinated children
http://www.vaccineinjury.info/…/survey-results-illnesses.ht…
Interview with PhD Immunologist, Dr Tetyana Obukhanych- part 1, by Catherine Frompovich
http://tinyurl.com/7guruq6
Vaccines Backfire: Veterinary Vaccines Found to Combine Into New Infectious Viruses
http://www.sciencedaily.com/releases/2012/…/120712144754.htm
A National and State Profile of Leading Health Problems and Health Care Quality for US Children: Key Insurance Disparities and Across-State Variations
http://www.sciencedirect.com/…/article/pii/S1876285910002500
The Questionable Contribution of Medical Measures to the Decline of Mortality in the United States in the Twentieth Century
This file is a PDF http://www.columbia.edu/…/clie…/readings/week_2/mckinlay.pdf
High Rate of Acellular Pertussis Vaccine Failure in Pre-Adolescents in a North American Outbreak
This file is a PDF http://www.immunizeca.org/…/CIC-2012-Sum…/Presenter-Witt.pdf
Aluminum in vaccines may be linked to health risks
http://www.straight.com/…/aluminum-vaccines-may-be-linked-h…
Vaccine-Nation: ‘Globally-supported company is funding fatal polio shots:
http://tribune.com.pk/…/vaccine-nation-globally-supported-…/
FDA 21 CFR Part 630, [Docket No. 84N-0178] Additional Standards for Viral Vaccines; Poliovirus Vaccine, Live, Oral: “However, although the continued availability of the vaccine may not be in immediate jeopardy, any possible doubts, whether or not well founded, about the safety of the vaccine cannot be allowed to exist”
(See last page, top of middle column: click top link to download)
http://tinyurl.com/88k77o4
A Judicial Watch Special Report: Examining the FDA’s HPV Vaccine Records
This file is a PDF http://www.judicialwatch.org/…/JWReportFDAhpvVaccineRecords…
Live virus used in polio vaccine can evolve and infect, warns TAU researcher
http://www.news-medical.net/…/Live-virus-used-in-polio-vacc…
The Present Status of Polio Vaccines – Transcript published in Illinois Medical Journal
http://s45.photobucket.com/…/Ang…/Present%20Status%20Polio/…
Recombinant HPV DNA found in multiple samples of Gardasil
http://sanevax.org/sane-vax-to-fda-recombinant-hpv-dna-fou…/
Warning bells against HPV vaccines (Rate of cervical cancer in US is about 3 per 100,000)
http://www.dailymail.co.uk/…/Warning-bells-HPV-vaccines.htm…
Lies, Damned Lies, and Medical Science
http://www.theatlantic.com/…/lies-damned-lies-and-med…/8269/
Response to influenza vaccine in adjuvant 65-4
(Peanut oil used as an adjuvant)
This file is a PDF http://www.ncbi.nlm.nih.gov/…/PMC213…/pdf/jhyg00071-0101.pdf
Gut Inflammation and Autism
http://the-scientist.com/2011/02/01/opening-a-can-of-worms/
Vaccine and medication safety are parents’ top research priorities
http://www2.med.umich.edu/prmc/media/newsroom/details.cfm
Thomson Reuters-NPR health poll: Vaccines
http://healthcare.thomsonreuters.com/…/NPR_report_vaccines.…
Alternative Vaccination Schedule Preferences Among Parents of Young Children
http://pediatrics.aappublications.org/conte…/…/848.abstract…
Frequency of Alternative Immunization Schedule Use in a Metropolitan Area
http://pediatrics.aappublications.org/…/peds.2011-3154.abst…
Italian court reignites MMR vaccine debate after award over child with autism
http://tinyurl.com/bvo2puj
States ending free parent whooping vaccine
http://www.news.com.au/…/state…/story-e6frfku0-1226350174856
Public Accounts and Estimates Committee – Ending Cocooning for Whooping Cough – Committee Testimony – see pgs 26-27
http://www.parliament.vic.gov.au/…/PAEC_Budget_estimates_12…
Three Young People From the Same Danish Town Have All Suffered Loss of Hearing in the Aftermath of MMR-Vaccination
http://nbjour.wordpress.com/…/three-young-people-from-the-…/
The Insanity Virus
http://discovermagazine.com/…/03-the-insanity…/article_view…
Potential Role of Parents’ Work Exposures in Autism Risk Examined: Possible Link Between Some Work Exposures and Risk for Offspring
http://www.sciencedaily.com/releases/2012/…/120312113902.htm
Vaccine bombshell: Baby monkeys given standard doses of popular vaccines develop autism symptoms
http://www.naturalnews.com/035787_vaccines_autism_monkeys.h
Merck & Co., Inc.: Lawsuit Claims Merck Overstated Mumps Vaccine Effectiveness
http://tinyurl.com/7j877qk
A Drumbeat on Profit Takers
http://www.nytimes.com/…/…/a-drumbeat-on-profit-takers.html…
Recommendation to place a moratorium on aluminum in vaccines in France by French Assembly Committee
This file is a PDF http://pdf.20mn.fr/2012/autres/ge-vaccination.pdf
google translation:
This file is a PDF http://translate.google.com/translate
What lies behind the low rates of vaccinations among nurses who treat infants?
This file is a PDF http://www.vaccineliberationarmy.com/…/What-lies-behind-the…
Amish farm kids remarkably immune to allergies: study
http://www.reuters.com/…/us-kidsallergies-idUSBRE8431J92012…
Vaccines for Children Program: Vulnerabilities in Vaccine Management
This file is a PDF http://oig.hhs.gov/oei/reports/oei-04-10-00430.pdf

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Vaccinations: To Prick or not to prick?

Just had a discussion about vaccinations: There is a lot of information out there about pros and cons of vaccines. Unfortunately much of the information is biased one way or the other. Here are some comments worth considering.  This is an article about puppies and dogs mostly, but some reference to 2 legged individuals is mentioned.

The timing: of the vaccinations are important.  To be protective the puppy/baby/kitten needs to have a vaccine given AFTER the maternal antibody levels have waned, otherwise mum’s antibodies nullify the antigen injection.  “Annual boosters” are NOT necessary and contribute to dis-ease. The dog’s immunity post vaccination lasts for many years, if not life- which is similar to MMR- you only really need one vaccine for life. The Mother’s antibodies (in the bitch and in humans!) come through the colostrum milk and provide immunity to the baby/puppy as long as there is breast feeding continuing, and while the babie’s gut is immature. The gut seals itself and the mother’s antibodies reduce by the 16th week of age. Vaccines are necessary then to give the bub its own immune push, and we recommend ONLY the NECESSARY core vaccines- DH&P (this is dogs! not humans- stick with me…I am a Naturopath and a Vet!).

REACTIONS: We do see vaccination reactions in puppies as well, unfortunately.  Holistic vets have recognised this for over 30 years, and have been integral in pushing the Veterinary group to recognise this!

 The type of vaccinations are also important considerations, (oral, intranasal, injection etc)the injectable bordatella causes major BAD reactions- anaphylaxis and death. Don’t do that one! the intranasal vaccine works and does not have the same negative reactions. DH&P reactions occur, usually after the second or 12-14 week shot. Its not common, but it is commonly missed! The reactions include GME (Ganulomatous Meningo Encephalitides), arthritides, skin reactions, autoimmune diseases- such as hypothyroidism, and possibly “Autism” or “hasn’t been right since” The problem arises more commonly in the very small white fluffy breeds. It’s likely a dose dependent problem and maybe related to the open blood brain barrier when the animal is teething. Vaccines should NOT be given to sick or ill animals.  Here is an article about vaccination reactions in dogs:

 What this means for humans is open to conjecture, but certainly one should vaccinate for ONLY the diseases present and with “good” vaccines which are modified live, that do not have mercury, formalin, artificial dyes (sets up food and insect allergy) and should NOT be given to sick or ill children- if you have Pyroluria or MTHFR genetics you should take supplements/give them to the kid prior. Thuja homeopathic may be useful, and giving 1/2 doses to small breeds and supplementing with vitamin E, vitamin B and spirulina provides methylation detox help. The accumulated evidence indicates that vaccination protocols should no longer be considered as a “one size fits all” program. Giving too much vaccinal antigen to a small breed puppy also can increase the risk of adverse reactions.http://drjeandoddspethealthresource.tumblr.com/…/dodds

What are vaccines and what are their purpose?
Vaccines are biological preparations used to stimulate immunity to a disease. They commonly contain a piece of infectious agent (bacteria or virus) that has been changed to make them less dangerous but more stimulating to the immune system. They do this usually by being killed or “live attenuated”. Most these days are live attenuated or modified live. The vaccine also contains “adjuvants”: additives that boost the immune response. These adjuvants are things like aluminium. They also contain preservatives to stop them becoming contaminated.  The commonly used vaccines in dogs contain several organisms together: eg the C3 vaccine contains three viruses; the C5 contains 5 infectious agents (the core 3 viruses and 2 agents of kennel cough).  Vaccines are delivered into the body in different ways. Most commonly they are injected under the skin. In the case of kennel cough vaccines, they can be delivered “locally” into the nose.

Why are vaccinations important?
Vaccinations are important to protect against infectious disease, especially those that can kill. In dogs these are the core vaccines, against distemper, infectious hepatitis and parvo virus. Vaccination programs have successfully reduced the number cases of deadly, infectious viruses and in so doing have made dogs healthier. Distemper, which was common when I was a child, is now almost non-existent. Likewise parvo virus, which swept the world in an epidemic in the 70’s and was rampant in the 80’s, is much less commonly seen. This is largely due to vaccination.

Vaccines also protect against common, but not fatal illnesses like kennel cough. Like a flu vaccine, it is possible to catch the illness, but symptoms are usually less severe. These are called “non-core vaccines”.

How effective are vaccines?

 Vaccines are general speaking very effective at producing immunity if used appropriately. They do however vary in their effectiveness to produce immunity in an individual animal. The effectiveness depends on several factors, including:

1.       The strain of the infectious agent used in the vaccine (some strains produce a strong immune response, such as the newer parvo vaccines).
2.       Completing a proper vaccination schedule (multiple doses are typically needed, at correctly spaced intervals)
3.       The individual genetic predisposition of each dog (some may be overly sensitive to the vaccines and more prone to side effects, whilst other individuals do not develop sufficient immunity despite being properly vaccinated).

Are there any problems or side effects with vaccines?

YES!! It is important that you know this. Vaccines are not benign, harmless substances. They work by affecting the immune system and can have long term, far reaching effects on it. There are three main categories of side effects or problems.  There is much more information here: u. There is much more on Dr Jean Dodds sites. http://www.britfeld.com/vaccination-adverse.htm

The first one is the least dramatic and most common: local pain or swelling at the injection site. This usually passes within a day or two. Just be careful handling your dog or puppy in that area.

The second one is quite uncommon and is an acute, sudden anaphylactic (allergic) reaction to the vaccine. The dog may become ill in the hours following vaccination: common signs are aches and pains, fevers and chills, reluctance to move. Rarely your dog or puppy may show other signs of neurological, gastro-intestinal, or respiratory disturbance. Mostly these are mild but occasionally strong and severe reactions are recorded. Veterinary assistance should be sought. DO NOT VACCINATE your dog again if your pet has ever experienced a vaccination reaction, as it is likely to be worse next time.

The third category is a delayed immunological response, up to 45 days afterwards. The signs commonly include milder symptoms like fever, stiffness, sore tummy, sore joints, increased susceptibility to infections, itchy skin and ears. Rarely, stronger signs are seen, including neurological and brain disorders, blood and bleeding disorders, liver and kidney failure and bone marrow suppression. We highly recommend titre testing in lieu of revaccinating atopic or itchy dogs, as we have seen them become increasingly pruritic each year following vaccination. After all, vaccinations are there to prime the immune system and make them more hyperactive.

Why are there such side effects from vaccines?

 We are still trying to understand all that goes on when we vaccinate, and afterwards. It is thought that a number of factors are involved including

1.       Using more effective (stronger) modified live (attenuated) vaccines.
2.       Possible preservatives, adjuvants and contaminants.
3.       “over-vaccinating”: giving a booster every year. Latest research shows that most dogs only need a booster as an adult every 3-5 years minimum.
4.       Mixing too many agents together in one vaccine: this provides too great a challenge at once.
5.       Vaccinating animals when they are stressed or unwell.
6.       Giving the agents by injection, rather than locally into the area affected.

What can we do then to maximize the benefits of vaccinations and reduce the harm and side effects?

1.       Only vaccinate your dog or puppy when they are healthy and not stressed.
2.       Do not give heartworm injections or other treatments at the same time. Wait two weeks at least.
3.       Have your dog receive the minimum number of puppy vaccines and adult boosters.
4.       Replace the annual booster vaccination visit with a full wellness exam, including blood tests.
5.       Ask your vet to use only “core vaccines” by injection : distemper, hepatitis and parvo virus (C3)
6.       Kennel cough vaccine, if needed, is best administered in the nose.
7.       If multiple injections are needed (eg to cover for leptospirosis as well) then wait at least two weeks between them. Use the minimum number of  agents at any one time.
8.       Do not vaccinate your dog against giardia or corona virus. These diseases are rare and the vaccines provide questionable immunity.
9.       Do not vaccinate puppies younger than 8 weeks.
10.    Seek veterinary advice regarding vaccination for geriatric animals and those with chronic health issues.

What vaccination protocol is recommended then?

 Puppies: I recommend two vaccines only, and do not give any before 8 weeks of age. Final vaccines can be given at 11 or 12 weeks, if your vet is using one of the newer products, such as nobivac. This means your puppy can be fully protected and out and about with all important socializing from 13 weeks.

Teenagers: Give a first booster 12 months after the final puppy vaccination. It is not necessary to vaccinate again sooner than this.

Adults: Do a blood test every year (titre test) to check if immunity is low and if a booster vaccination is required. Titre tests are available for the core vaccines but not for kennel cough. If boosters are needed for kennel cough for boarding, agility, showing etc, then the intranasal vaccine is recommended.

If your dog does not need a kennel cough booster for one of these reasons, then I suggest you pass on this and keep to a healthy diet and lifestyle and immune boosting supplements instead.

Train yourself to go to see your vet for an annual wellness exam for your dog: NOT a booster vaccination. The wellness exam should include blood work for titre test, and any other tests you and your vet deem necessary or important.

In Conclusion:
Vaccines are important tools in keeping your dog healthy. However, they need to used carefully to cause no harm. Please discuss vaccination for your pet with your vet. If in doubt, a second opinion never hurts. There is also lots of information available regarding vaccines and vaccination protocols. W Jean Dodds of California, USA is a world authority and research leader in this field. I highly recommend her work to you.