Practice “Safe Stress!”

DCIM100GOPROLet’s face it, life is becoming increasingly busy with work, family, social media, and things that go beep all around us. All this stimulation sets off our internal alarm buttons, and gives our physical bodies unnecessary alerts. The messages we receive tell us that it’s hard to stay afloat of all the events and time commitments around us.   It can make you  feel like you are drowning in paper work, or going under with financial burdens. Many feel overwhelmed with commitments or unfinished projects.

STRESS!  Stress!  Stress!

It’s a killer. It’s the NUMBER ONE cause of all illnesses!  I must admit that I didn’t believe it until I felt the effects. Its A sneaky– under the radar– black cloud that just niggles at your adrenal glands until you have nothing more to put out, and find yourself struggling to get out of bed in the morning, or tossing and turning unable to fall asleep at night —Stress_2without popping a pill.  Curiously most of us just don’t recognise that we have this monkey on our back, until we actually do fall apart with some physical signs, such as autoimmune diseases, diabetes, hypertension, rheumatoid arthritis, allergic skin disorders, back aches, disc diseases, Digestive problems,  Cancer (through lowering your immune vigilance) heart palpitations and fibrillation or Thyroid conditions.

Image by Gdudycha :  The effects of stress on the body.

Stress from too much emotional, physical, or mental stimulation needs to be calmed. Stress causes your adrenals to push out the hormones of adrenaline, noradrenaline and cortisol. This can lead to inflammation and wear and tear on your body, it also pushes up your blood sugar and insulin levels, leading to that middle belly fat store and liver diseases.

Some stress is ok, but when we continually burn our adrenals and force them to pump out stress hormones, our bodies go to ground. PTSD or post traumatic stress disorder is a longer term effect.

Nurture and nourish your body and soul. You are here for the long haul, not just for a couple of exams or a University course, a stressful job, parenting a child with autism, or a difficult marriage, or a speeding ticket.  There options and ways to handle your stress levels, even if you cannot completely control your environment/relationship/job.

Here are  top 7 stress busters:

  1. Organize- Clutter control is the key to staying organized. Keep a wastebasket close by and throw away things that you no longer need. Dedicate at least 15 minutes of your time to organizing your study area so you do not have to waste time sorting through rubbles of books and papers when looking for something. Remove and give away excess clothing, pottery, kitchen ware, magazines, newspapers.
  2. Learn how to say “No”- Don’t get over-involved. You don’t have to join every activity, every club, and every community project. You do not have to accept all invitations to socialize with friends. Evaluate your schedule and check your to-do list to see what tasks are important and accomplish them first.
  3. Exercise- Regular exercise releases muscle tension and will rev up your energy. Join a yoga class, Qi Gong, Tai Chi, Swim, go for a walk with a friend, or get up and dance in your living room. You don’t need fancy exercise machines to get regular exercise. Any type of exercise is good for your body and mind. Take a break daily to smell the grass, roses and exercise at the same time. DSC_0720
  4. Eat nutritiously- Students, nurses, doctors and busy housewives, executives and police officers are notorious for not eating right. A healthy diet can enhance your body and mental functions. A poor diet can zap you of brainpower. So grab a fruit, a veggie plate, or nutrition bar when you are hungry or have no time to prepare a healthy meal.
  5. Get enough sleep- Students, shift workers, and Medical professionals  are among the most sleep-deprived group of people due to over-commitment. Getting enough sleep will rebuild your energy and will make you feel better.
  6. Herbal Helpers- The gardening principle comes into play when nourishing your body- to last a lifetime, you will need to spend a lifetime looking after your adrenals, “weed out” the stress by removing yourself from stressful situations, and feed them well replenish them with some of the following herbs at periods of stress with these adaptogens: Withania somnifera= Ashwaganda, Rehmannia glutinosa, Rhodiola, American Ginseng (Panax quinquefolius), Astragalus membranaceus, Bacopa monnieri, Eleutherococcus senticosus (Siberian Ginseng).  See a Naturopath for a consultation to tweak your own personal herbal formula.
  7. Essential oils- Good quality oils and aromatherapy massages can help your brain and adrenals recover. The oils must be of a therapeutic non contaminated blend and individualised for the person’s requirements, preferably by seeing a qualified aromatherapist. Some useful blends might include some of the following: Bergamot, Patchouli, Blood Orange, Ylang Ylang, Chamomile, Jasmine, Lavender, Rose, Sandlewood, and Grapefruit essential oils.

And lastly, remember to SMILE!    Life is a present. Open yourself to receiving JOY.

Hug your dog, neighbour’s dog, friends dog…..or get a nice well behaved and friendly dog- they make you smile!

DSC_0561smile pup

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Vaccinology: for those that need to see the science

….here are 332 studies which show the other side of the issue.
To believe vaccination is 100 effective and that it does not have any major side effects is an absolute contortion of the scientific facts. To make vaccination mandatory takes away our freedom of choice and makes a mockery of informed consent. There is a humans rights issue involved here too with regards to mandatory vaccination.” – scroll down to see the studies:
Link Between Neurologic and Immune Disorders
Aluminum
Aluminum Vaccine Adjuvants: Are they Safe?
http://www.ncbi.nlm.nih.gov/pubmed/21568886
Mechanisms of aluminum adjuvant toxicity and autoimmunity in pediatric populations
http://lup.sagepub.com/content/21/2/223.short
Aluminum hydroxide injections lead to motor deficits and motor neuron degeneration
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819810/
Long-term Persistence of Vaccine-Derived Aluminum Hydroxide is Associated with Chronic Cognitive Dysfunction
http://www.sciencedirect.com/…/article/pii/S0162013409001895
Long-term follow-up of cognitive dysfunction in patients with aluminum hydroxide-induced macrophagic myofasciitis (MMF).
http://www.sciencedirect.com/…/article/pii/S0162013411002194
Do aluminum vaccine adjuvants contribute to the rising prevalence of autism?
http://www.ncbi.nlm.nih.gov/pubmed/22099159
Aluminum Adjuvant Linked to Gulf War Illness Induces Motor Neuron Death in Mice
http://www.springerlink.com/content/x457214811q62412/
The immunobiology of aluminium adjuvants: how do they really work?
http://www.sciencedirect.com/…/article/pii/S1471490609002488
Aluminum inclusion macrophagic myofasciitis: a recently identified condition
http://www.ncbi.nlm.nih.gov/pubmed/14753387
Macrophagic myofasciitis lesions assess long-term persistence of vaccine-derived aluminium hydroxide in muscle
http://brain.oxfordjournals.org/content/…/1821.full.pdf+html
A role for the body burden of aluminium in vaccine-associated macrophagic myofasciitis and chronic fatigue syndrome
http://www.medical-hypotheses.com/…/S0306-9877(08)…/abstract
Aluminum as an adjuvant in Crohn’s disease induction
http://lup.sagepub.com/content/21/2/231.abstract
Aluminum is a potential environmental factor for Crohn’s disease induction: extended hypothesis
http://www.ncbi.nlm.nih.gov/pubmed/17804561
DNA released from dying host cells mediates aluminum adjuvant activity
http://www.nature.com/nm/journal/v17/n8/full/nm.2403.html
Mercury
Sorting out the spinning of autism: heavy metals and the question of incidence
This file is a PDF http://www.ane.pl/pdf/7021.pdf
Comparison of blood and brain mercury levels in infant monkeys exposed to methylmercury or vaccines containing thimerosal
http://www.ncbi.nlm.nih.gov/pubmed/16079072
A Case Series of Children with Apparent Mercury Toxic Encephalopathies Manifesting with Clinical Symptoms of Regressive Autistic Disorders
http://www.ncbi.nlm.nih.gov/pubmed/17454560
Neurodevelopmental disorders following thimerosal-containing childhood immunizations: a follow-up analysis
http://www.ncbi.nlm.nih.gov/pubmed/15764492
Persistent behavioral impairments and alterations of brain dopamine system after early postnatal administration of thimerosal in rats
http://www.ncbi.nlm.nih.gov/pubmed/21549155
Maternal thimerosal exposure results in aberrant cerebellar oxidative stress, thyroid hormone metabolism, and motor behavior in rat pups; sex- and strain-dependent effects
http://www.ncbi.nlm.nih.gov/pubmed/22015705
Neonatal administration of thimerosal causes persistent changes in mu opioid receptors in the rat brain
http://www.ncbi.nlm.nih.gov/pubmed/20803069
Integrating experimental (in vitro and in vivo) neurotoxicity studies of low-dose thimerosal relevant to vaccines
http://www.ncbi.nlm.nih.gov/pubmed/21350943
Thimerosal-Derived Ethylmercury Is a Mitochondrial Toxin in Human Astrocytes: Possible Role of Fenton Chemistry in the Oxidation and Breakage of mtDNA
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395253/
Activation of methionine synthase by insulin-like growth factor-1 and dopamine: a target for neurodevelopmental toxins and thimerosal
http://www.ncbi.nlm.nih.gov/pubmed/14745455
Administration of thimerosal to infant rats increases overflow of glutamate and aspartate in the prefrontal cortex: protective role of dehydroepiandrosterone sulfate.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264864/
Neurologic and Immune Development
The Emerging Link Between Autoimmune Disorders and Neuropsychiatric Disease
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086677/
Influence of pediatric vaccines on amygdala growth and opioid ligand binding in rhesus macaque infants: A pilot study
This file is a PDF http://www.ane.pl/pdf/7020.pdf
Primary Immunization of Premature Infants with Gestational Age <35 Weeks: Cardiorespiratory Complications and C-Reactive Protein Responses Associated with Administration of Single and Multiple Separate Vaccines Simultaneously
http://www.jpeds.com/article/S0022-3476(07)00185-0/abstract
Neonatal administration of thimerosal causes persistent changes in mu opioid receptors in the rat brain
http://www.ncbi.nlm.nih.gov/pubmed/20803069
Maternal thimerosal exposure results in aberrant cerebellar oxidative stress, thyroid hormone metabolism, and motor behavior in rat pups; sex- and strain-dependent effects
http://www.ncbi.nlm.nih.gov/pubmed/22015705
Administration of thimerosal to infant rats increases overflow of glutamate and aspartate in the prefrontal cortex: protective role of dehydroepiandrosterone sulfate.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264864/
Molecular mechanisms underlying anti-inflammatory phenotype of neonatal splenic macrophages
http://www.jleukbio.org/content/82/2/403.full.pdf+html
Abnormal measles-mumps-rubella antibodies and CNS autoimmunity in children with autism
http://www.ncbi.nlm.nih.gov/pubmed/12145534
Integrating experimental (in vitro and in vivo) neurotoxicity studies of low-dose thimerosal relevant to vaccines
http://www.ncbi.nlm.nih.gov/pubmed/21350943
Serological association of measles virus and human herpesvirus-6 with brain autoantibodies in autism
http://www.ncbi.nlm.nih.gov/pubmed/9756729
In Harm’s Way: Toxic Threats to Child Development
http://action.psr.org/site/DocServer/frontmatter.pdf
Novel roles for immune molecules in neural development: implications for neurodevelopmental disorders (Many toxic insults discussed but not vaccines.)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059681/
Immune Activation in Brain Aging and Neurodegeneration: Too Much or Too Little?
http://www.sciencedirect.com/…/article/pii/S0896627309006771
Neurologic and Immune Dysfunction
Primary Immunization of Premature Infants with Gestational Age <35 Weeks: Cardiorespiratory Complications and C-Reactive Protein Responses Associated with Administration of Single and Multiple Separate Vaccines Simultaneously
http://www.jpeds.com/article/S0022-3476(07)00185-0/abstract
Neurodevelopmental disorders following thimerosal-containing childhood immunizations: a follow-up analysis
http://www.ncbi.nlm.nih.gov/pubmed/15764492
Persistent behavioral impairments and alterations of brain dopamine system after early postnatal administration of thimerosal in rats
http://www.ncbi.nlm.nih.gov/pubmed/21549155
Maternal thimerosal exposure results in aberrant cerebellar oxidative stress, thyroid hormone metabolism, and motor behavior in rat pups; sex- and strain-dependent effects
http://www.ncbi.nlm.nih.gov/pubmed/22015705
Administration of thimerosal to infant rats increases overflow of glutamate and aspartate in the prefrontal cortex: protective role of dehydroepiandrosterone sulfate
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264864/
A possible central mechanism in autism spectrum disorders, part 1
http://www.ncbi.nlm.nih.gov/pubmed/19043938
A possible central mechanism in autism spectrum disorders, part 2: immunoexcitotoxicity
http://www.ncbi.nlm.nih.gov/pubmed/19161050
A possible central mechanism in autism spectrum disorders, part 3: the role of excitotoxin food additives and the synergistic effects of other environmental toxins
http://www.ncbi.nlm.nih.gov/pubmed/19284184
Oily adjuvants and autoimmunity: now time for reconsideration?
http://lup.sagepub.com/content/21/2/217.abstract
Evidence of Mitochondrial Dysfunction in Autism and Implications for Treatment
This file is a PDF http://www.icdrc.org/documents/Mitoandautism2008.pdf
Fatal outcome after postexposure rabies vaccination in a patient with Parkinson’s disease
http://www.ncbi.nlm.nih.gov/pubmed/15675624
Specific Vaccines
Neurological Complications of Pertussis Immunization
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025848/?page=1
DPT Vaccine and Chronic Nervous System Dysfunction: A New Analysis
http://www.nap.edu/catalog.php?record_id=9814#toc
Abnormal measles-mumps-rubella antibodies and CNS autoimmunity in children with autism
http://www.ncbi.nlm.nih.gov/pubmed/12145534
Pertussis toxin is required for pertussis vaccine encephalopathy
This file is a PDF http://www.ncbi.nlm.nih.gov/…/PMC391…/pdf/pnas00364-0469.pdf
Hepatitis B triple series vaccine and developmental disability in US children aged 1-9 years
http://www.tandfonline.com/doi/abs/10.1080/02772240701806501
CNS demyelination and quadrivalent HPV vaccination
http://msj.sagepub.com/content/15/1/116.short
Increased Incidence and Clinical Picture of Childhood Narcolepsy following the 2009 H1N1 Pandemic Vaccination Campaign in Finland
http://www.plosone.org/…/info%3Adoi%2F10.1371%2Fjournal.pon…
Safety and immunogenicity of H5N1 vaccine
http://www.thelancet.com/…/PIIS0140-6736(06)69891-7/fulltext
Child influenza vaccination: Ramifications of adverse events in children in Australia
http://www.bmj.com/content/340/bmj.c2994
Progression of Renal Disease in Henoch-Schönlein Purpura After Influenza Vaccination
(Click PDF in upper right corner for full text)
http://jama.jamanetwork.com/article.aspx?articleid=367705
Henoch–Schönlein purpura following meningitis C vaccination
http://rheumatology.oxfordjournals.org/content/40/3/345.full
Fatal outcome after postexposure rabies vaccination in a patient with Parkinson’s disease
http://www.ncbi.nlm.nih.gov/pubmed/15675624
Brain Inflammation (encephalitis) Post Vaccination
Neurological Complications of Pertussis Immunization
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025848/?page=1
Acute disseminated encephalomyelitis
http://www.neurology.org/content/68/16_suppl_2/S23.abstract
Acute disseminated encephalomyelitis following influenza vaccination
Full text available by clicking PDF in upper right corner
http://archneur.jamanetwork.com/article.aspx
A Case Series of Children with Apparent Mercury Toxic Encephalopathies Manifesting with Clinical Symptoms of Regressive Autistic Disorders
http://www.ncbi.nlm.nih.gov/pubmed/17454560
Vaccination against Whooping-Cough: Efficacy versus Risks
http://www.sciencedirect.com/…/article/pii/S0140673677910285
DPT Vaccine and Chronic Nervous System Dysfunction: A New Analysis
http://www.nap.edu/catalog.php?record_id=9814#toc
Acute disseminated encephalomyelitis
http://pmj.bmj.com/content/79/927/11.full
Pertussis toxin is required for pertussis vaccine encephalopathy
This file is a PDF http://www.ncbi.nlm.nih.gov/…/PMC391…/pdf/pnas00364-0469.pdf
Acute necrotizing encephalopathy secondary to diphtheria, tetanus toxoid and whole-cell pertussis vaccination: diffusion-weighted imaging and proton MR spectroscopy findings
http://www.springerlink.com/content/44xt417387hx4877/
The smallpox vaccine and postvaccinal encephalitis
http://www.ncbi.nlm.nih.gov/pubmed/12170398
Encephalo-Myelitis following Vaccination
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2047920/
Encephalo-Myelitis following Vaccination
http://actx.beta.download.thelancet.com/…/PIIS0140…/fulltext
Subacute sclerosing panencephalitis–the continuing threat
Deaths Attributable to Smallpox Vaccination, 1959 to 1966, and 1968
Click PDF in upper right corner for full text.
http://jama.jamanetwork.com/article.aspx
Acute encephalopathy and chronic neurological damage after pertussis vaccine
http://www.ncbi.nlm.nih.gov/pubmed/7906066
Encephalopathies following prophylactic pertussis vaccine
http://pediatrics.aappublications.org/content/…/437.abstract
Treatment of lethal pertussis vaccine reaction with histamine H1 antagonists
http://www.neurology.org/content/37/6/1068
Murine model for pertussis vaccine encephalopathy: linkage to H-2
http://www.nature.com/…/journal/v299/n5885/abs/299738a0.html
Autoimmune Disease
‘ASIA’ – Autoimmune/Inflammatory Syndrome
‘ASIA’ – Autoimmune/Inflammatory Syndrome Induced by Adjuvants
http://www.ncbi.nlm.nih.gov/pubmed/20708902
The spectrum of ASIA: ‘Autoimmune (Auto-inflammatory) Syndrome induced by Adjuvants’
http://lup.sagepub.com/content/21/2/118.full.pdf+html
ASIA: A New Way to Put the Puzzle Together: Autoimmune (autoinflammatory) syndrome induced by adjuvants provides a diagnostic framework for enigmatic conditions
http://www.the-rheumatologist.org/…/ASIA_A_New_Way_to_Put_t…
Induction of the ‘ASIA’ syndrome in NZB/NZWF1 mice after injection of complete Freund’s adjuvant (CFA)
http://lup.sagepub.com/content/21/2/203.abstract
The common immunogenic etiology of chronic fatigue syndrome: from infections to vaccines via adjuvants to the ASIA syndrome
http://www.ncbi.nlm.nih.gov/pubmed/22054760
Shoenfeld’s Syndrome After Pandemic Influenza A/H1N1 Vaccination (Download free full text by clicking ACTA Reumatologica Portuguesa in upper right corner.)
http://www.ncbi.nlm.nih.gov/pubmed/21483283
Human Adjuvant Disease Induced by Foreign Substances: A New Model of ASIA
http://lup.sagepub.com/content/21/2/128.full.pdf+html
Gulf War Syndrome as a part of the autoimmune (autoinflammatory) syndrome induced by adjuvant (ASIA)
http://lup.sagepub.com/content/21/2/190.abstract
Adjuvant Immunization Induces High Levels of Pathogenic Antiphospholipid Antibodies in Genetically Prone Mice: Another Facet of the ASIA Syndrome
http://lup.sagepub.com/content/21/2/210.abstract
Autoimmunity Following Hepatitis B Vaccine as Part of the Spectrum of ‘Autoimmune (Auto-inflammatory) Syndrome Induced by Adjuvants’ (ASIA): analysis of 93 cases
http://lup.sagepub.com/content/21/2/146.abstract
Macrophagic Myofasciitis
Macrophagic myofasciitis lesions assess long-term persistence of vaccine-derived aluminium hydroxide in muscle
http://brain.oxfordjournals.org/content/…/1821.full.pdf+html
Macrophagic myofasciitis: characterization and pathophysiology
http://lup.sagepub.com/content/21/2/184.abstract
Lessons From Macrophagic Myofasciitis: Towards Definition of a Vaccine Adjuvant-Related Syndrome
http://www.ncbi.nlm.nih.gov/pubmed/12660567
AlOH3-adjuvanted vaccine-induced macrophagic myofasciitis in rats is influenced by the genetic background
http://www.ncbi.nlm.nih.gov/pubmed/16616846
Multiple Sclerosis and Demyelinating Disease
Recombinant Hepatitis B Vaccine and the Risk of Multiple Sclerosis: a Prospective Study
http://www.ncbi.nlm.nih.gov/pubmed/15365133
CNS Demyelination and Quadrivalent HPV Vaccination
http://msj.sagepub.com/content/15/1/116.short
Asthma and Allergy
Is infant immunization a risk factor for childhood asthma or allergy?
http://www.ncbi.nlm.nih.gov/pubmed/9345669
Infection of Human B Lymphocytes with MMR Vaccine Induces IgE Class Switching
http://www.ncbi.nlm.nih.gov/pubmed/11513549
Delay in diphtheria, pertussis, tetanus vaccination is associated with a reduced risk of childhood asthma
http://www.jacionline.org/ar…/S0091-6749(07)02379-2/fulltext
Effects of diphtheria-tetanus-pertussis or tetanus vaccination on allergies and allergy-related respiratory symptoms among children and adolescents in the United States
http://www.ncbi.nlm.nih.gov/pubmed/10714532
Vaccination and Allergic Disease: A Birth Cohort Study
(Interesting to note that the data show a risk of allergic disease after vaccination but the authors dismiss it in their conclusion.)
http://ajph.aphapublications.org/…/pdf/10.2105/AJPH.94.6.985
The relationship between vaccine refusal and self-report of atopic disease in children
http://www.sciencedirect.com/…/article/pii/S0091674905000266
Rheumatic Disease
Immunization of patients with autoimmune inflammatory rheumatic diseases (the EULAR recommendations)
http://lup.sagepub.com/content/21/2/162.abstract
Chronic Arthritis after Rubella Vaccination
http://cid.oxfordjournals.org/content/15/2/307.short
Autoimmune response following influenza vaccination in patients with autoimmune inflammatory rheumatic disease
http://lup.sagepub.com/content/21/2/175.abstract
Giant cell arteritis and polymyalgia rheumatica after influenza vaccination: report of 10 cases and review of the literature
http://lup.sagepub.com/content/21/2/153.abstract
Diabetes
Pertussis infections, vaccines and Type 1 diabetes
http://onlinelibrary.wiley.com/…/j.1464-5491.2004.0114…/full
Clustering of cases of type 1 diabetes mellitus occurring 2-4 years after vaccination is consistent with clustering after infections and progression to type 1 diabetes mellitus in autoantibody positive individuals
http://www.ncbi.nlm.nih.gov/pubmed/12793601
Clustering of cases of insulin dependent diabetes (IDDM) occurring three years after hemophilus influenza B (HiB) immunization support causal relationship between immunization and IDDM
http://www.ncbi.nlm.nih.gov/pubmed/12482192
Vaccines and the risk of insulin-dependent diabetes (IDDM): potential mechanism of action
http://www.medical-hypotheses.com/…/S0306-9877(01)…/abstract
Italian pediatric data support hypothesis that simultaneous epidemics of type 1 diabetes and type 2 diabetes/metabolic syndrome/obesity are polar opposite responses (i.e., symptoms) to a primary inflammatory condition
http://www.degruyter.com/…/…/jpem.2011.023/jpem.2011.023.xml
Specific Vaccines and Autoimmunity
Abnormal measles-mumps-rubella antibodies and CNS autoimmunity in children with autism
http://www.ncbi.nlm.nih.gov/pubmed/12145534
Autoimmune hazards of hepatitis B vaccine
http://www.sciencedirect.com/…/article/pii/S1568997204002010
Vaccine Model of Antiphospholipid Syndrome Induced by Tetanus Vaccine
http://lup.sagepub.com/content/21/2/195.abstract
Influenza vaccination can induce new-onset anticardiolipins but not ß2-glycoprotein-I antibodies among patients with systemic lupus erythematosus
http://lup.sagepub.com/content/21/2/168.abstract
Influenza and autoimmunity
http://onlinelibrary.wiley.com/…/j.1749-6632.2009.…/abstract
Systemic lupus erythematosus following HPV immunization or infection?
http://lup.sagepub.com/content/21/2/158.abstract
Early diphtheria-tetanus-pertussis vaccination associated with higher female mortality and no difference in male mortality in a cohort of low birthweight children: an observational study within a randomised trial
http://adc.bmj.com/…/20…/02/13/archdischild-2011-300646.full
Effects of diphtheria-tetanus-pertussis or tetanus vaccination on allergies and allergy-related respiratory symptoms among children and adolescents in the United States
http://www.ncbi.nlm.nih.gov/pubmed/10714532
Henoch–Schönlein purpura following meningitis C vaccination
http://rheumatology.oxfordjournals.org/content/40/3/345.full
Other Autoimmune Diseases
Characterization of antigen-presenting dendritic cells in the peripheral blood and colonic mucosa of patients with ulcerative colitis
http://www.ncbi.nlm.nih.gov/pubmed/11474315
Polymerase chain reaction detection of the hemagglutinin gene from an attenuated measles vaccine strain in the peripheral mononuclear cells of children with autoimmune hepatitis
http://www.springerlink.com/content/tln20u18374r4q30/
Early Childhood Membranous Nephropathy Due to Cationic Bovine Serum Albumin (Though not mentioned by the authors, Bovine Serum is in vaccines.)
http://www.nejm.org/doi/full/10.1056/NEJMoa1013792
The common immunogenic etiology of chronic fatigue syndrome: from infections to vaccines via adjuvants to the ASIA syndrome
http://www.ncbi.nlm.nih.gov/pubmed/22054760
General Autoimmunity Issues
Vaccines and autoimmunity
http://www.nature.com/…/jo…/v5/n11/abs/nrrheum.2009.196.html
Vaccine-induced Autoimmunity
http://www.sciencedirect.com/…/article/pii/S0896841196900918
Mechanisms of aluminum adjuvant toxicity and autoimmunity in pediatric populations
http://lup.sagepub.com/content/21/2/223.short
The Emerging Link Between Autoimmune Disorders and Neuropsychiatric Disease
This file is a PDF http://www.ncbi.nlm.nih.gov/…/PMC3086677/pdf/nihms284704.pdf
Serological association of measles virus and human herpesvirus-6 with brain autoantibodies in autism
http://www.ncbi.nlm.nih.gov/pubmed/9756729
Adjuvant Immunization Induces High Levels of Pathogenic Antiphospholipid Antibodies in Genetically Prone Mice: Another Facet of the ASIA Syndrome
http://lup.sagepub.com/content/21/2/210.abstract
Self-Organized Criticality Theory of Autoimmunity
http://www.plosone.org/…/info%3Adoi%2F10.1371%2Fjournal.pon…
Gut-Brain-Immune System Connection and Function Development
Autism: an emerging ‘neuroimmune disorder’ in search of therapy
http://informahealthcare.com/…/abs/10.1517/14656560903107789
Normal gut microbiota modulates brain development and behavior
http://www.pnas.org/content/108/7/3047.full
Novel roles for immune molecules in neural development: implications for neurodevelopmental disorders
(Many toxic insults discussed but not vaccines.)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059681/
Immune Proteins in Brain Development and Synaptic Plasticity
http://www.sciencedirect.com/…/article/pii/S0896627309006783
Function
Gastrointestinal Pathology in Autism Spectrum Disorders: The Venezuelan Experience
http://www.scribd.com/…/Gastrointestinal-Pathology-in-Autis…
Clinical Presentation and Histologic Findings at Ileocolonoscopy in Children with Autistic Spectrum Disorder and Chronic Gastrointestinal Symptoms
(Click “Download Paper” for full text)
http://www.la-press.com/clinical-presentation-and-histologi
Characterization of antigen-presenting dendritic cells in the peripheral blood and colonic mucosa of patients with ulcerative colitis
http://www.ncbi.nlm.nih.gov/pubmed/11474315
A possible central mechanism in autism spectrum disorders, part 1
http://www.ncbi.nlm.nih.gov/pubmed/19043938
A possible central mechanism in autism spectrum disorders, part 2: immunoexcitotoxicity
http://www.ncbi.nlm.nih.gov/pubmed/19161050
A possible central mechanism in autism spectrum disorders, part 3: the role of excitotoxin food additives and the synergistic effects of other environmental toxins
http://www.ncbi.nlm.nih.gov/pubmed/19284184
Efficacy of methylcobalamin and folinic acid treatment on glutathione redox status in children with autism
http://www.ajcn.org/content/89/1/425.long
Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2610366/
Oxidative stress-related biomarkers in autism: Systematic review and meta-analyses
http://www.sciencedirect.com/…/article/pii/S0891584912001827
Immune-glutamatergic dysfunction as a central mechanism of the autism spectrum disorders
http://www.benthamdirect.org/pages/content.php
Central and Peripheral Cytokines Mediate Immune-Brain Connectivity
http://www.springerlink.com/content/f6718rl3g2k75656/
No Antibodies Required For Immunity Against Some Viruses: B Cell Maintenance of Subcapsular Sinus Macrophages Protects against a Fatal Viral Infection Independent of Adaptive Immunity
http://www.cell.com/immunity/abstract/S1074-7613(12)00057-X
Immune Activation in Brain Aging and Neurodegeneration: Too Much or Too Little?
http://www.sciencedirect.com/…/article/pii/S0896627309006771
Connection
Autism: an emerging ‘neuroimmune disorder’ in search of therapy
http://informahealthcare.com/…/abs/10.1517/14656560903107789
Molecular mechanisms underlying anti-inflammatory phenotype of neonatal splenic macrophages
http://www.jleukbio.org/content/82/2/403.full.pdf+html
Central and Peripheral Cytokines Mediate Immune-Brain Connectivity
http://www.springerlink.com/content/f6718rl3g2k75656/
Children with autism spectrum disorders (ASD) who exhibit chronic gastrointestinal (GI) symptoms and marked fluctuation of behavioral symptoms exhibit distinct innate immune abnormalities and transcriptional profiles of peripheral blood (PB) monocytes
http://www.jni-journal.com/a…/S0165-5728(11)00191-3/abstract
Panenteric IBD-Like Disease in a Patient with Regressive Autism Shown for the First Time by the Wireless Capsule Enteroscopy: Another Piece in the Jigsaw of this Gut-Brain Syndrome?
http://www.nature.com/…/journ…/v100/n4/full/ajg2005166a.html
Clinical Presentation and Histologic Findings at Ileocolonoscopy in Children with Autistic Spectrum Disorder and Chronic Gastrointestinal Symptoms
(Click “Download Paper” for full text)
http://www.la-press.com/clinical-presentation-and-histologi
Effectiveness of the gluten-free, casein-free diet for children diagnosed with autism spectrum disorder:
(Based on parental report)
http://www.ncbi.nlm.nih.gov/pubmed/22564339
Hypothesis: Conjugate vaccines may predispose children to autism spectrum disorders
http://www.sciencedirect.com/…/article/pii/S0306987711004117
A possible central mechanism in autism spectrum disorders, part 1
http://www.ncbi.nlm.nih.gov/pubmed/19043938
A possible central mechanism in autism spectrum disorders, part 2: immunoexcitotoxicity
http://www.ncbi.nlm.nih.gov/pubmed/19161050
A possible central mechanism in autism spectrum disorders, part 3: the role of excitotoxin food additives and the synergistic effects of other environmental toxins
http://www.ncbi.nlm.nih.gov/pubmed/19284184
Immune-glutamatergic dysfunction as a central mechanism of the autism spectrum disorders
http://www.benthamdirect.org/pages/content.php
Immune Activation in Brain Aging and Neurodegeneration: Too Much or Too Little?
http://www.sciencedirect.com/…/article/pii/S0896627309006771
Autism
Metals and Environmental Toxins in Autism
Sorting out the spinning of autism: heavy metals and the question of incidence
This file is a PDF http://www.ane.pl/pdf/7021.pdf
Neurodevelopmental disorders following thimerosal-containing childhood immunizations: a follow-up analysis
http://www.ncbi.nlm.nih.gov/pubmed/15764492
A Case Series of Children with Apparent Mercury Toxic Encephalopathies Manifesting with Clinical Symptoms of Regressive Autistic Disorders
http://www.ncbi.nlm.nih.gov/pubmed/17454560
Persistent behavioral impairments and alterations of brain dopamine system after early postnatal administration of thimerosal in rats
http://www.ncbi.nlm.nih.gov/pubmed/21549155
Neonatal administration of thimerosal causes persistent changes in mu opioid receptors in the rat brain
http://www.ncbi.nlm.nih.gov/pubmed/20803069
Do aluminum vaccine adjuvants contribute to the rising prevalence of autism?
This file is a PDF http://omsj.org/reports/tomljenovic%202011.pdf
Administration of thimerosal to infant rats increases overflow of glutamate and aspartate in the prefrontal cortex: protective role of dehydroepiandrosterone sulfate
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264864/
Mercury in first-cut baby hair of children with autism versus typically-developing children
http://www.tandfonline.com/d…/abs/10.1080/02772240701699294…
Mercury induces inflammatory mediator release from human mast cells
http://www.biomedcentral.com/1742-2094/7/20
Maternal thimerosal exposure results in aberrant cerebellar oxidative stress, thyroid hormone metabolism, and motor behavior in rat pups; sex- and strain-dependent effects
http://www.ncbi.nlm.nih.gov/pubmed/22015705
How environmental and genetic factors combine to cause autism: A redox/methylation hypothesis
http://www.sciencedirect.com/…/article/pii/S0161813X0700215X
Comparison of blood and brain mercury levels in infant monkeys exposed to methylmercury or vaccines containing thimerosal
http://www.ncbi.nlm.nih.gov/pubmed/16079072
Integrating experimental (in vitro and in vivo) neurotoxicity studies of low-dose thimerosal relevant to vaccines
http://www.ncbi.nlm.nih.gov/pubmed/21350943
Thimerosal-Derived Ethylmercury Is a Mitochondrial Toxin in Human Astrocytes: Possible Role of Fenton Chemistry in the Oxidation and Breakage of mtDNA
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395253/
Neuroimmune Disorders in Autism
Influence of pediatric vaccines on amygdala growth and opioid ligand binding in rhesus macaque infants: A pilot study
This file is a PDF http://www.ane.pl/pdf/7020.pdf
Persistent behavioral impairments and alterations of brain dopamine system after early postnatal administration of thimerosal in rats
http://www.ncbi.nlm.nih.gov/pubmed/21549155
Neurodevelopmental disorders following thimerosal-containing childhood immunizations: a follow-up analysis
http://www.ncbi.nlm.nih.gov/pubmed/15764492
Neonatal administration of thimerosal causes persistent changes in mu opioid receptors in the rat brain
http://www.ncbi.nlm.nih.gov/pubmed/20803069
Abnormal measles-mumps-rubella antibodies and CNS autoimmunity in children with autism
http://www.ncbi.nlm.nih.gov/pubmed/12145534
Maternal thimerosal exposure results in aberrant cerebellar oxidative stress, thyroid hormone metabolism, and motor behavior in rat pups; sex- and strain-dependent effects
http://www.ncbi.nlm.nih.gov/pubmed/22015705
Serological association of measles virus and human herpesvirus-6 with brain autoantibodies in autism
http://www.ncbi.nlm.nih.gov/pubmed/9756729
Autism: an emerging ‘neuroimmune disorder’ in search of therapy
http://informahealthcare.com/…/abs/10.1517/14656560903107789
Administration of thimerosal to infant rats increases overflow of glutamate and aspartate in the prefrontal cortex: protective role of dehydroepiandrosterone sulfate.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264864/
A possible central mechanism in autism spectrum disorders, part 1
http://www.ncbi.nlm.nih.gov/pubmed/19043938
A possible central mechanism in autism spectrum disorders, part 2: immunoexcitotoxicity
http://www.ncbi.nlm.nih.gov/pubmed/19161050
A possible central mechanism in autism spectrum disorders, part 3: the role of excitotoxin food additives and the synergistic effects of other environmental toxins
http://www.ncbi.nlm.nih.gov/pubmed/19284184
Evidence of Mitochondrial Dysfunction in Autism and Implications for Treatment
This file is a PDF http://www.icdrc.org/documents/Mitoandautism2008.pdf
Neuroglial activation and neuroinflammation in the brain of patients with autism
http://www.ncbi.nlm.nih.gov/pubmed/15546155
Thimerosal-Derived Ethylmercury Is a Mitochondrial Toxin in Human Astrocytes: Possible Role of Fenton Chemistry in the Oxidation and Breakage of mtDNA
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395253/
Environment and Genetics in Autism
Genetic Heritability and Shared Environmental Factors Among Twin Pairs With Autism
http://archpsyc.jamanetwork.com/article.aspx
How environmental and genetic factors combine to cause autism: A redox/methylation hypothesis
http://www.sciencedirect.com/…/article/pii/S0161813X0700215X
Theoretical aspects of autism: Causes—A review
http://informahealthcare.com/…/abs/10.…/1547691X.2010.545086
Gastrointestinal Disease in Autism
Children with autism spectrum disorders (ASD) who exhibit chronic gastrointestinal (GI) symptoms and marked fluctuation of behavioral symptoms exhibit distinct innate immune abnormalities and transcriptional profiles of peripheral blood (PB) monocytes
http://www.jni-journal.com/a…/S0165-5728(11)00191-3/abstract
Panenteric IBD-Like Disease in a Patient with Regressive Autism Shown for the First Time by the Wireless Capsule Enteroscopy: Another Piece in the Jigsaw of this Gut-Brain Syndrome?
http://www.nature.com/…/journ…/v100/n4/full/ajg2005166a.html
Clinical Presentation and Histologic Findings at Ileocolonoscopy in Children with Autistic Spectrum Disorder and Chronic Gastrointestinal Symptoms
(Click “Download Paper” for full text)
http://www.la-press.com/clinical-presentation-and-histologi
Gastrointestinal Pathology in Autism Spectrum Disorders: The Venezuelan Experience
http://www.scribd.com/…/Gastrointestinal-Pathology-in-Autis…
Autistic enterocolitis: Fact or fiction?
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694587/
Autistic Enterocolitis: Confirmation of a New Inflammatory Bowel Disease in An Italian Cohort of Patients
http://www.latitudes.org/forums/index.php?showtopic=1409
Specific Vaccines and Autism
Abnormal measles-mumps-rubella antibodies and CNS autoimmunity in children with autism
http://www.ncbi.nlm.nih.gov/pubmed/12145534
Hypothesis: Conjugate vaccines may predispose children to autism spectrum disorders
http://www.sciencedirect.com/…/article/pii/S0306987711004117
Hepatitis B Vaccination of Male Neonates and Autism, NHIS 1997–2002
http://www.tandfonline.com/…/p…/10.1080/15287394.2010.519317
Elevated levels of measles antibodies in children with autism
http://www.sciencedirect.com/…/article/pii/S0887899402006276
Methylation in Autism
Efficacy of methylcobalamin and folinic acid treatment on glutathione redox status in children with autism
http://www.ajcn.org/content/89/1/425.long
Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2610366/
Oxidative stress-related biomarkers in autism: Systematic review and meta-analyses
http://www.sciencedirect.com/…/article/pii/S0891584912001827
How environmental and genetic factors combine to cause autism: A redox/methylation hypothesis
http://www.sciencedirect.com/…/article/pii/S0161813X0700215X
Thimerosal-Derived Ethylmercury Is a Mitochondrial Toxin in Human Astrocytes: Possible Role of Fenton Chemistry in the Oxidation and Breakage of mtDNA
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395253/
Unexplained Infant Death
Infant mortality rates regressed against number of vaccine doses routinely given: is there a biochemical or synergistic toxicity?
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170075/
Primary Immunization of Premature Infants with Gestational Age <35 Weeks: cardiorespiratory Complications and C-Reactive Protein Responses Associated with Administration of Single and Multiple Separate Vaccines Simultaneously
http://www.jpeds.com/article/S0022-3476(07)00185-0/abstract
Unexplained cases of sudden infant death shortly after hexavalent vaccination
http://www.sciencedirect.com/…/article/pii/S0264410X05004688
Unexplained cases of sudden infant death shortly after hexavalent vaccination – rebuttal
http://www.murciasalud.es/archivo.php?id=88521
Simultaneous sudden infant death syndrome
http://www.ncbi.nlm.nih.gov/pubmed/17654772
Treatment of lethal pertussis vaccine reaction with histamine H1 antagonists.
http://www.neurology.org/content/37/6/1068
Murine model for pertussis vaccine encephalopathy: linkage to H-2.
http://www.nature.com/…/journal/v299/n5885/abs/299738a0.html
Chronic Illness
Emergent Human Pathogen Simian Virus 40 and Its Role in Cancer
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC452549/
‘ASIA’ – autoimmune/inflammatory syndrome induced by adjuvants
http://www.ncbi.nlm.nih.gov/pubmed/20708902
The common immunogenic etiology of chronic fatigue syndrome: from infections to vaccines via adjuvants to the ASIA syndrome
http://www.ncbi.nlm.nih.gov/pubmed/22054760
Aluminum as an adjuvant in Crohn’s disease induction
http://lup.sagepub.com/content/21/2/231.abstract
Aluminum is a potential environmental factor for Crohn’s disease induction: extended hypothesis
http://www.ncbi.nlm.nih.gov/pubmed/17804561
Characterization of antigen-presenting dendritic cells in the peripheral blood and colonic mucosa of patients with ulcerative colitis
http://www.ncbi.nlm.nih.gov/pubmed/11474315
The relationship between vaccine refusal and self-report of atopic disease in children
http://www.sciencedirect.com/…/article/pii/S0091674905000266
Antibodies to Saccharomyces cerevisiae in Crohn’s disease: Higher titers are associated with a greater frequency of mutant NOD2/CARD15 alleles and with a higher probability of complicated disease
http://onlinelibrary.wiley.com/doi/10.1002/ibd.20031/full
This item pairs with the link just above: The antigen is harvested and purified from fermentation cultures of a recombinant strain of the yeast Saccharomyces cerevisiae
This file is a PDF http://www.merck.com/…/pi…/r/recombivax_hb/recombivax_pi.pdf
Thimerosal-Derived Ethylmercury Is a Mitochondrial Toxin in Human Astrocytes: Possible Role of Fenton Chemistry in the Oxidation and Breakage of mtDNA
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395253/
Viral Infection and Neurologic Dysfunction
Antibodies to measles in individuals with recent onset psychosis
http://www.schres-journal.com/…/S0920-9964(09)0060…/abstract
Elevated levels of measles antibodies in children with autism
http://www.pedneur.com/artic…/S0887-8994(02)00627-6/abstract
The human endogenous retrovirus link between genes and environment in multiple sclerosis and in multifactorial diseases associating neuroinflammation
http://www.ncbi.nlm.nih.gov/pubmed/19697163
Endogenous retroviral genes, Herpesviruses and gender in Multiple Sclerosis
http://www.ncbi.nlm.nih.gov/pubmed/19447411
Endogenous retrovirus type W GAG and envelope protein antigenemia in serum of schizophrenic patients
http://www.ncbi.nlm.nih.gov/pubmed/18760403
The multiple sclerosis-associated retrovirus and its HERV-W endogenous family: a biological interface between virology, genetics, and immunology in human physiology and disease
http://www.ncbi.nlm.nih.gov/pubmed/19039700
Infection and Autoimmunity
http://wwwnc.cdc.gov/eid/article/12/3/05-1409_article.htm
The common immunogenic etiology of chronic fatigue syndrome: from infections to vaccines via adjuvants to the ASIA syndrome
http://www.ncbi.nlm.nih.gov/pubmed/22054760
Influenza and autoimmunity
http://onlinelibrary.wiley.com/…/j.1749-6632.2009.…/abstract
Subacute sclerosing panencephalitis–the continuing threat
(cut and paste link to download PDF)
hrcak.srce.hr/file/43654
Other Complications Post Vaccination
Emergent Human Pathogen Simian Virus 40 and Its Role in Cancer
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC452549/
Adverse Events following 12 and 18 Month Vaccinations: a Population-Based, Self-Controlled Case Series Analysis
http://www.plosone.org/…/info%3Adoi%2F10.1371%2Fjournal.pon…
Increased Incidence and Clinical Picture of Childhood Narcolepsy following the 2009 H1N1 Pandemic Vaccination Campaign in Finland
http://www.plosone.org/…/info%3Adoi%2F10.1371%2Fjournal.pon…
Henoch–Schönlein purpura following meningitis C vaccination
http://rheumatology.oxfordjournals.org/content/40/3/345.full
Fatal outcome after postexposure rabies vaccination in a patient with Parkinson’s disease
http://www.ncbi.nlm.nih.gov/pubmed/15675624
Discolored Leg Syndrome Following Vaccines:
http://www.ncbi.nlm.nih.gov/pubmed/18546020
Adverse Effects of Vaccines: Evidence and Causality
(From the text: The committee finds that evidence convincingly supports a causal relationship between some vaccines and some adverse events…evidence favors rejection of five vaccine-adverse event relationships… However, for the majority of cases (135 vaccine-adverse event pairs), the evidence was inadequate to accept or reject a causal relationship.”
http://www.iom.edu/…/Adverse-Effects-of-Vaccines-Evidence-a…
Vaccination Efficacy, Failure, and Disease Transmission
Disease Transmission
Attenuated vaccines can recombine to form virulent field viruses
http://www.sciencemag.org/content/337/6091/188.abstract
Sibling Transmission of Vaccine-Derived Rotavirus (RotaTeq) Associated With Rotavirus Gastroenteritis
This file is a PDF http://pediatrics.aappublications.org/…/peds.2009-1901.full…
The Evolutionary Consequences of Blood-Stage Vaccination on the Rodent Malaria Plasmodium chabaudi
http://www.plosbiology.org/…/info%3Adoi%2F10.1371%2Fjournal…(Ambra+-+Biology+New+Articles
Vaccine-acquired Rotavirus Infection in Two Infants with Severe Combined Immunodeficiency
http://www.jacionline.org/ar…/S0091-6749(09)00151-1/fulltext
Long-Term Circulation of Vaccine-Derived Poliovirus That Causes Paralytic Disease
http://jvi.asm.org/content/76/13/6791.full
Molecular and Antigenic Characterization of a Highly Evolved Derivative of the Type 2 Oral Poliovaccine Strain Isolated from Sewage in Israel
http://jcm.asm.org/content/38/10/3729.full
Prevalence of vaccine-derived polioviruses in the environment
http://jgv.sgmjournals.org/content/83/5/1107.full
Transmission of mumps virus from mumps-vaccinated individuals to close contact
http://www.ncbi.nlm.nih.gov/pubmed/21983359
Adventitious Agents and Vaccines
http://www.ncbi.nlm.nih.gov/…/a…/PMC2631857/pdf/11485673.pdf
Efficacy Issues/Failure
Why Do Pertussis (Whooping Couvh) Vaccines Fail?
http://pediatrics.aappublications.org/conte…/…/5/968.extract
Unexpectedly limited durability of immunity following acellular pertussis vaccination in preadolescents in a North American outbreak
http://cid.oxfordjournals.org/content/54/12/1730.abstract
Selection of Hepatitis B Virus (HBV) Vaccine Escape Mutants in HBV-Infected and HBV/HIV-Coinfected Patients Failing Antiretroviral Drugs With Anti-HBV Activity
http://journals.lww.com/…/Selection_of_Hepatitis_B_Virus__H…
Measles outbreak in a fully immunized secondary-school population
http://www.ncbi.nlm.nih.gov/pubmed/3821823
Acellular pertussis vaccination facilitates Bordetella parapertussis infection in a rodent model of bordetellosis.
http://www.ncbi.nlm.nih.gov/pubmed/20200027
Mumps outbreak among vaccinated university students associated with a large party, the Netherlands, 2010
http://www.sciencedirect.com/…/article/pii/S0264410X12006299
Waning Protection after Fifth Dose of Acellular Pertussis Vaccine in Children
http://www.nejm.org/doi/full/10.1056/NEJMoa1200850
Review of the United States universal varicella vaccination program: Herpes zoster incidence rates, cost-effectiveness, and vaccine efficacy based
primarily on the Antelope Valley Varicella Active Surveillance Project data
http://www.sciencedirect.com/…/article/pii/S0264410X12007761
Effectiveness of Jeryl Lynn-containing vaccine in Spanish children
http://www.ncbi.nlm.nih.gov/pubmed/19356610
Mumps Orchitis in the Post-Vaccine Era (1967Y2009)
This file is a PDF http://www.vaccine-tlc.org/docs/Mumps.pdf
Considerations for Viral Disease Eradication: Lessons Learned and Future Strategies
Quote: Important and often overlooked, mass vaccinations itself can also exert tremendous selective pressures and lead to the evolution of new infectious agents.
http://books.nap.edu/openbook.php?record_id=10424&page=R1
Recent Resurgence of Mumps in the United States
http://www.nejm.org/doi/full/10.1056/NEJMoa0706589#t=article
Risk of vaccine failure after Haemophilus influenzae type b (Hib) combination vaccines with acellular pertussis
http://www.thelancet.com/…/PIIS0140-6736(03)13171-6/fulltext
Subacute sclerosing panencephalitis–the continuing threat
(cut and paste link to download PDF)
http://www.hrcak.srce.hr/file/43654
Questionable Science and Policy
Placebos
What’s in Placebos: Who Knows? Analysis of Randomized, Controlled Trials
http://www.ncbi.nlm.nih.gov/pubmed/20956710
Testing vaccines in pediatric research subjects
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831649/
Policy
Adverse Effects of Vaccines: Evidence and Causality
(From the text: The committee finds that evidence convincingly supports a causal relationship between some vaccines and some adverse events…evidence favors rejection of five vaccine-adverse event relationships… However, for the majority of cases (135 vaccine-adverse event pairs), the evidence was inadequate to accept or reject a causal relationship.”
http://www.iom.edu/…/Adverse-Effects-of-Vaccines-Evidence-a…
Human papillomavirus (HPV) vaccine policy and evidence-based medicine: Are they at odds?
http://informahealthcare.com/…/abs/10.…/07853890.2011.645353
The Number Needed to Vaccinate to Prevent Infant Pertussis Hospitalization and Death Through Parent Cocoon Immunization
http://cid.oxfordjournals.org/…/…/12/01/cid.cir836.abstract…
The Evolutionary Consequences of Blood-Stage Vaccination on the Rodent Malaria Plasmodium chabaudi
http://www.plosbiology.org/…/info%3Adoi%2F10.1371%2Fjournal…(Ambra+-+Biology+New+Articles
Selection of Hepatitis B Virus (HBV) Vaccine Escape Mutants in HBV-Infected and HBV/HIV-Coinfected Patients Failing Antiretroviral Drugs With Anti-HBV Activity
http://journals.lww.com/…/Selection_of_Hepatitis_B_Virus__H…
Influenza Vaccination During Pregnancy: A Critical Assessment of the Recommendations of the Advisory Committee on Immunization Practices (ACIP)
http://www.jpands.org/vol11no2/ayoub.pdf
Review of the United States universal varicella vaccination program: Herpes zoster incidence rates, cost-effectiveness, and vaccine efficacy based primarily on the Antelope Valley Varicella Active Surveillance Project data http://www.sciencedirect.com/…/article/pii/S0264410X12007761
Adverse events and quadrivalent human papillomavirus recombinant vaccine
http://jama.jamanetwork.com/article.aspx
Attenuated vaccines can recombine to form virulent field viruses
http://www.sciencemag.org/content/337/6091/188.abstract
Mandatory HPV Vaccination
http://jama.jamanetwork.com/article.aspx?articleid=1104867
Acellular pertussis vaccination facilitates Bordetella parapertussis infection in a rodent model of bordetellosis.
http://www.ncbi.nlm.nih.gov/pubmed/20200027
No autoimmune safety signal after vaccination with quadrivalent HPV vaccine Gardasil?
http://tinyurl.com/72uvrb2
Influenza vaccination: policy versus evidence
http://www.bmj.com/content/333/7574/912%2523TBL2.full
Human papillomavirus vaccine trials in India
http://www.thelancet.com/…/PIIS0140-6736(11)60270-5/fulltext
Australia suspends seasonal flu vaccination of young children
http://www.bmj.com/content/340/bmj.c2419
Australia suspends seasonal flu vaccination of young children
http://www.bmj.com/…/adverse-events-following-influenza-vac…
Child influenza vaccination: Ramifications of adverse events in children in Australia
http://www.bmj.com/content/340/bmj.c2994
Vaccine safety: current systems and recent findings
http://journals.lww.com/…/Vaccine_safety__current_systems_a…
Excess mortality from seasonal influenza is negligible below the age of 50 in Israel: implications for vaccine policy
http://www.springerlink.com/content/2p44p50005827585/
Adventitious Agents and Vaccines
http://www.ncbi.nlm.nih.gov/…/a…/PMC2631857/pdf/11485673.pdf
Why Do Pertussis Vaccines Fail?
http://pediatrics.aappublications.org/conte…/…/5/968.extract
Vaccine Contamination
Mercury in vaccines from the Australian childhood immunization program schedule
http://www.ncbi.nlm.nih.gov/pubmed/20391108
Quantitation of DNA and Protein Impurities in Biopharmaceuticals -Liver Cancer?
http://pubs.acs.org/doi/abs/10.1021/ac00009a003
Cloned Hepatitis B Virus DNA causes hepatitis in chimpanzees
This file is a PDF http://www.nature.com/natu…/journal/…/n5885/pdf/299740a0.pdf
The Dangerous Impurities of Vaccines
http://www.scribd.com/patro…/d/49973741-Dangerous-Impurities
Adventitious Agents and Vaccines
http://www.ncbi.nlm.nih.gov/…/a…/PMC2631857/pdf/11485673.pdf
Veterinary Research
Attenuated vaccines can recombine to form virulent field viruses
http://www.sciencemag.org/content/337/6091/188.abstract
Vaccine-associated acute polyneuropathy resembling Guillain-Barré syndrome in a dog
http://www.mendeley.com/…/vaccineassociated-acute-polyneur…/
Viral status and antibody response in cattle inoculated with recombinant bovine leukemia virus-vaccinia virus vaccines after challenge exposure with bovine leukemia virus-infected lymphocytes
http://www.ncbi.nlm.nih.gov/pubmed/8725805
Interesting Articles, etc.
Vaccines for Children Program: Vulnerabilities in Vaccine Management
http://oig.hhs.gov/oei/reports/oei-04-10-00430.pdf
Guide to Vaccine Contraindications and Precautions – CDC
http://www.cdc.gov/…/downlo…/contraindications-guide-508.pdf
Charts Comparing Dead Babies to Vaccine Timeline:
http://therefusers.com/…/dead-babies-and-stillbirths-repor…/
Unvaccinated Children Are Healthier
This file is a PDF http://www.vaccineinjury.info/imag…/stories/ias1992study.pdf
State of health of unvaccinated children
http://www.vaccineinjury.info/…/survey-results-illnesses.ht…
Interview with PhD Immunologist, Dr Tetyana Obukhanych- part 1, by Catherine Frompovich
http://tinyurl.com/7guruq6
Vaccines Backfire: Veterinary Vaccines Found to Combine Into New Infectious Viruses
http://www.sciencedaily.com/releases/2012/…/120712144754.htm
A National and State Profile of Leading Health Problems and Health Care Quality for US Children: Key Insurance Disparities and Across-State Variations
http://www.sciencedirect.com/…/article/pii/S1876285910002500
The Questionable Contribution of Medical Measures to the Decline of Mortality in the United States in the Twentieth Century
This file is a PDF http://www.columbia.edu/…/clie…/readings/week_2/mckinlay.pdf
High Rate of Acellular Pertussis Vaccine Failure in Pre-Adolescents in a North American Outbreak
This file is a PDF http://www.immunizeca.org/…/CIC-2012-Sum…/Presenter-Witt.pdf
Aluminum in vaccines may be linked to health risks
http://www.straight.com/…/aluminum-vaccines-may-be-linked-h…
Vaccine-Nation: ‘Globally-supported company is funding fatal polio shots:
http://tribune.com.pk/…/vaccine-nation-globally-supported-…/
FDA 21 CFR Part 630, [Docket No. 84N-0178] Additional Standards for Viral Vaccines; Poliovirus Vaccine, Live, Oral: “However, although the continued availability of the vaccine may not be in immediate jeopardy, any possible doubts, whether or not well founded, about the safety of the vaccine cannot be allowed to exist”
(See last page, top of middle column: click top link to download)
http://tinyurl.com/88k77o4
A Judicial Watch Special Report: Examining the FDA’s HPV Vaccine Records
This file is a PDF http://www.judicialwatch.org/…/JWReportFDAhpvVaccineRecords…
Live virus used in polio vaccine can evolve and infect, warns TAU researcher
http://www.news-medical.net/…/Live-virus-used-in-polio-vacc…
The Present Status of Polio Vaccines – Transcript published in Illinois Medical Journal
http://s45.photobucket.com/…/Ang…/Present%20Status%20Polio/…
Recombinant HPV DNA found in multiple samples of Gardasil
http://sanevax.org/sane-vax-to-fda-recombinant-hpv-dna-fou…/
Warning bells against HPV vaccines (Rate of cervical cancer in US is about 3 per 100,000)
http://www.dailymail.co.uk/…/Warning-bells-HPV-vaccines.htm…
Lies, Damned Lies, and Medical Science
http://www.theatlantic.com/…/lies-damned-lies-and-med…/8269/
Response to influenza vaccine in adjuvant 65-4
(Peanut oil used as an adjuvant)
This file is a PDF http://www.ncbi.nlm.nih.gov/…/PMC213…/pdf/jhyg00071-0101.pdf
Gut Inflammation and Autism
http://the-scientist.com/2011/02/01/opening-a-can-of-worms/
Vaccine and medication safety are parents’ top research priorities
http://www2.med.umich.edu/prmc/media/newsroom/details.cfm
Thomson Reuters-NPR health poll: Vaccines
http://healthcare.thomsonreuters.com/…/NPR_report_vaccines.…
Alternative Vaccination Schedule Preferences Among Parents of Young Children
http://pediatrics.aappublications.org/conte…/…/848.abstract…
Frequency of Alternative Immunization Schedule Use in a Metropolitan Area
http://pediatrics.aappublications.org/…/peds.2011-3154.abst…
Italian court reignites MMR vaccine debate after award over child with autism
http://tinyurl.com/bvo2puj
States ending free parent whooping vaccine
http://www.news.com.au/…/state…/story-e6frfku0-1226350174856
Public Accounts and Estimates Committee – Ending Cocooning for Whooping Cough – Committee Testimony – see pgs 26-27
http://www.parliament.vic.gov.au/…/PAEC_Budget_estimates_12…
Three Young People From the Same Danish Town Have All Suffered Loss of Hearing in the Aftermath of MMR-Vaccination
http://nbjour.wordpress.com/…/three-young-people-from-the-…/
The Insanity Virus
http://discovermagazine.com/…/03-the-insanity…/article_view…
Potential Role of Parents’ Work Exposures in Autism Risk Examined: Possible Link Between Some Work Exposures and Risk for Offspring
http://www.sciencedaily.com/releases/2012/…/120312113902.htm
Vaccine bombshell: Baby monkeys given standard doses of popular vaccines develop autism symptoms
http://www.naturalnews.com/035787_vaccines_autism_monkeys.h
Merck & Co., Inc.: Lawsuit Claims Merck Overstated Mumps Vaccine Effectiveness
http://tinyurl.com/7j877qk
A Drumbeat on Profit Takers
http://www.nytimes.com/…/…/a-drumbeat-on-profit-takers.html…
Recommendation to place a moratorium on aluminum in vaccines in France by French Assembly Committee
This file is a PDF http://pdf.20mn.fr/2012/autres/ge-vaccination.pdf
google translation:
This file is a PDF http://translate.google.com/translate
What lies behind the low rates of vaccinations among nurses who treat infants?
This file is a PDF http://www.vaccineliberationarmy.com/…/What-lies-behind-the…
Amish farm kids remarkably immune to allergies: study
http://www.reuters.com/…/us-kidsallergies-idUSBRE8431J92012…
Vaccines for Children Program: Vulnerabilities in Vaccine Management
This file is a PDF http://oig.hhs.gov/oei/reports/oei-04-10-00430.pdf

“I wish someone had told me that before I graduated”

Recently someone asked me to write a chapter in a book for new Veterinary graduates.
I thought it might be useful for many people of different walks of life, so here are my
TIWI KWIP’s — This cone of shame is a mnemonic word that specialists and “older” vintage  practitioners use to explain “Things I Wish I Knew When I was in Practice”
 I always enjoy listening to these lecturers, as their stories given with their “retrospectroscope” are illuminating and often a relief to hear that others had gone through your situation, bringing some hilarity to our subjective failings .  For instance the Professor of anaesthesiology was lecturing to us and relayed a humorous story about an Anaesthetist climbing the long ladder to heaven after he had passed away.  There was a long chalkboard next to the ladder, and after each step you had to place a chalk mark  next to the ladder for any mistakes you made in your life or any work related mishaps.  On his way up he met a surgeon he knew coming down, and he was surprised and somewhat concerned to see that this surgeon was heading the wrong way! “Hey, are you ok? Did you get rejected at the pearly gates?” he asked. “No, I just ran out of chalk, I’m coming down to get some more!” the surgeon said.
I hope, as you travel through your working life, that you realize that all the great Veterinarians that you respect, and that have gone before you, are there because they never gave up, and that they probably made all the mistakes that you perhaps will, or are going through right now.  Your licence to “practice” means just that- you will forever be “practicing” and learning. Listen to your colleagues, listen to your clients, avoid becoming judgemental, stay humble.  You are still the top of your High School league, and necessarily in the top 1% academically, so be aware that Veterinary Medicine and Surgery is not always clear sailing, and it is not always your fault. This does not mean that you shouldn’t acknowledge anything that did not go 100% smoothly, but remind yourself, and your clients, that we are dealing with biology, not changing an old tyre, and we cannot guarantee immortality at any cost. We can only do our best, with our heartfelt desire to help. The vast majority of our work will be an improvement for their pet, and we are definitely more knowledgeable than any other non- veterinarian out there giving advice on pet care.
There will be  many moments of mild, or even severe anxiety,  and several periods of doubt, during your first few years as a Veterinary Surgeon and Physician.  You will gain experience. Keep moving and seek help if you are feeling overwhelmed- because it’s actually a normal part of the process!  Many “disasters” are actually a lesson which in the future will help you to help someone else.  Cherish those, and remind yourself how well you recovered from that situation. Save your client thank you notes, and refer to the many outstanding successes you have had if you ever find yourself feeling down about your profession.
sunrise boys

First off remember that you are NOT ALONE.  You really do have friends and family that care, just go and find them.   Get social.  Talk to PEOPLE.  Off load your grief. The rate of suicide in the veterinary profession is unacceptably high.  It has been shown that those  vets who have a more balanced life, with a social supporting structure such as church, drama clubs, book clubs, soccer, netball, football have much less stress related illness. Exercise based activities that are routinely added to your week are a survival mechanism, it might seem a chore but just DO IT!  Find your TRIBE, so you have a sense of purpose and belonging. Tribes exist online (Facebook) and in real time in your community, its the niche- doing what you like together with a small group.
1) Develop an attitude of gratitude towards your boss and nurses. Bring food to share!  When you graduate you do not know everything and the nurses and staff often know a heck of a lot more than you. Be kind to the nurses especially, some of them may not seem worth it (they get stressed by new grads) but time will pass and you will improve.
2) Expect the unexpected– re spay– plan everything well, and something will happen that you didn’t expect, but don’t feel bad about that because next time you will do that better.   Everyone drops a spay pedicle in their first year, don’t panic, extend the incision and find the kidney in that area, its right under it.   Exteriorize and have good vision of the tract.  Don’t use thin  monofilament suture around the uterine stump in fat/peri-oestrous  as when the swelling happens (as it always does post) the material will cut into the tissue and the animal can bleed out from there.
3)  There are always more options than what you have been taught at Uni, consider referring if you are stumped- no shame in that: ophthalmology, Dentistry, Dermatologist, Internist referral, also “alternative medicine” to a qualified veterinarian trained in acupuncture, Chinese herbs, western herbs, essential oils, remedial massage, chiropractic, osteopathy- refer to your colleagues it will make you look AWESOME. (not dumb) if you get a patient that you cannot think of a way forward.  Visit your colleagues and watch them practice, see if you can be a trainee under their mentorship. Join the local journal club.
4) FAMILY first!  Make time for dating and looking after your partner and plan family fun times- your family is more important than work. However if they are very “needy” you might have to put in place some outside help, eg. if you are caring for elderly parents, an autistic child, or disabled partner, you need back up plans for when you are scheduled to work.  I have been both employer and employee, and understand both sides, however if an employer is looking after an family crisis member and their casual staff calls in at the last minute repeatedly to say they cannot work because their child has a head cold and cannot go to school – you can understand that this is really not the employer’s problem, even if government regulations in the workplace industry might allow some time off for parental leave. It’s important to be thoughtful of your colleague’s time.  Be kind to your workplace and have babysitters lined up to cover these incidences. There are paid agencies such as “Dial an Angel” and lovely grandmothers nearby, figure it out in advance, prior to your need!
Remember the saying “if you fail to plan, you are planninbaristag to fail”. Plan to make time for your family and help the practice plan to give you time off.
5) Nutrition! Don’t skip breakfast! Have 1gm of protein/kg of your body weight every day. If you  need to have a smoothie on the run, then do that. Plan nutritious stews for evening meals, a slow cooker and a rice cooker with steaming basket on top are essential to your growing family. Throw everything in the crockpot before you go to bed, and its done for the day!
6) Do 7 minutes of exercise everyday- this could be 1 minute of push ups, 1 minute of star jumps, 1 minute of planking, 1 minute of running on the spot, 1 minute of stair climbs and 1 minute each of side planking
fatcatI’m in shape! (Round is a shape, right?)You can watch the morning news while doing this.

7) Find a hobby- art, painting, pottery, snorkeling etc- you need to put GOOD pictures into your brain daily, to wipe out or replace the BAD pictures that will come in- the Hit by cars, the emotional client that blames you (incorrectly usually!) for not picking up their pets disease, the euthenasia where everyone cries etc- these all affect your adrenals and will give you a type of Post Traumatic Stress Disorder or PTSD.  You need to file these away and calm your hormones. Reset your Parasympathetic gut healing and remove the cortisol/adrenal rush.
8) See a Qualified Naturopath and an Integrative GP doctor–and ask for a referral to a specialist if necessary,  to help you cope and find strategies, supplements, and diet advice to get you back on track if you are feeling not quite 100%
9)  SMILE! It’s contagious–Do IT- even if you don’t feel like it. Be happy.  It is a choice.  Learn to meditate on that.
smile pup
Good luck and be well, go for the long haul– life journey!
Feel free to pop over to my wellness sites for more advice. https://www.facebook.com/Naturopathvet?fref=ts
Naturopathvet.com
Dr Elaine Cebuliak
Get your antioxidants in early in the day, and take large quantities!

Get your antioxidants in early in the day, and take large quantities!

ANIMAL WELLNESS ph 61 7 31221997
Veterinary Integrative Care Clinic AND Advanced Veterinary Dentistry
Greenslopes Shopping Mall
Shop 6B/700 Logan Road,
Greenslopes Qld 4120
www.animalwellness.com.au
http://www.facebook.com/?ref=home#!/animalwellness

https://naturopathvet.com/

Dr Elaine Cebuliak BVSc MACVSc dentistry, Dip Ed, Dip Rem Massage, Cert Chinese Herbs, Cert IVAS Qual Acupuncture, CMAVA, Adv Dip Naturopathy, Adv Dip Herbal Med, Adv Dip Nutrition       ph 61-422413404
http://www.pethealth.com.au/Page/animal-massage-brisbane

Detox your Pet!

Detox your pet!
We all want our health span to equal our life span, and we certainly want our pets  to live a happy, healthy and long life. Unfortunately we cannot make this an “eternal” or forever life – but we can try to help them bypass the poor quality events–arthritis, dermatoses, otitis externae (ear infections) and cancer caused by poor diets,  and toxins.
We know that readers of this magazine already know that the world is full of pollutants! Poisonous chemicals cumulate over time in our pet’s, and our own bodies usually stored in fat tissue which might become a nidus for tumour growth. Taking the “Rubbish out” is a life long/daily/weekly event – leading to a longer life (ask my husband!)
Harmful waste products are either flushed out –down the urine pathway filtered out  via our kidneys, or through our entero-hepatic cycle and out the other “hole”.  Some are sweated out via skin/ears which may be  represented as dermatitis and otitis
The simple answer to detox is to feed fresh, organic balanced foods that are species appropriate, and to provide ample sources of pure clean water. www.catinfo.org gives great information about feeding cats, and our clinic www.animalwellness.com.au can help with soecific diets.  Adding a good quality Spirulina or chlorella and Zeolite can help to bind out toxins that have accumulated in one’s body. If there is heavy metals- such as Lead -eg. in Mt Isa or Broken HIll mining towns, Zeolite given as small amounts weekly can help remove some of the toxicity. Each patient is an individual,  and the amount and type of detox will vary accordingly. Some animals- such as man, primates and guinea pigs require exceptional levels of vitamin C to prevent scurvy during the clearing process, and small amounts of vitamin B and Selenium are also necessary. A complete blood count and serum analysis prior to embarking on a diet change or “detox”  helpful to customize a particular organ system recovery.  For example, renal problems are helped to detoxify with the herb Rehmannia, and liver toxins are cleared with s-AME, milk thistle, dandelion root and vitamin B’s. All require thorough rehydration therapy.
  Where are these pollutants? Our pets, and us, drink them  in our water (fluoride, oestrogens “the birth control pills”, agricultural chemicals), and eat them in our food- insecticides, herbicides (GMO produce are glyphosate friendly-meaning you will get a big dose of BT toxins and Round up ready gut problems if you ingest corn, maize, wheat!  We also absorb them from our skin- which is a carrier NOT a barrier.  Avoid putting unnecessary toxins onto your, or your pet’s skin: Did you know that your skin is a carrier, NOT a barrier- as was previously thought. That means whatever you put On your skin is carried INTO your body and absorbed until it is eliminated. This has implications for nanoparticles in sunscreen (linked to cancer)  and phthalates and parabens in soaps, shampoos and cosmetics.
Bodies also produce endogenous toxins- that is stress and its dependent hormones- adrenaline, cortisol etc cause some wear and tear on internal tissues and produce some waste that also needs to be cleared out. Think your dog is chilled out and not stressed? Think again. Most little white fluffies (maltese, poodles, shitzu) just love and miss their owners so much that they can burn out their adrenals the same as their humans. Talk to an animal behaviourist to improve their attitude, and work on “Calm and mindful” pet therapy.

Check your food labels: Natural does not necessarily mean “Natural” as in “gift from Nature”.

It is commonly a marketing tool- it  means “can taste like a natural food” or smells like a “Nature derived smell” when in fact it can be entirely synthetic and made from plastics and coal tar- a by product of the petrochemical industry. Its a lot cheaper and therefore more profitable for the company  to , and make Liver, or chicken flavor and Red erythrosine dyes onto plastic “food” chews that so many dogs go Whacko from. (you know the TV commercial!)

Its the same for us- Vanilla, an orchid seed pod is very expensive to grow and then bottle.  That’s why most of your chocolate  (which of course you do NOT feed to your pets) and cookies use ethyl vanillin- its cheap, but WHAT is THAT doing to your body and organ systems- especially if your body has no way of breaking it down? Where is it stored (think fat, liver etc! ) and how is it removed from your body? Much of  it must pass through into urine and  faeces- because it is found in our seawater, which means both the liver and the kidneys had a “go” at filtering it.  What does it do the the environmental food chain then?

Some contaminants in our food chain bioaccumulate. This means that if it is in the soil or seawater (via sewerage)  the smaller organisms eat it, incorporate this into their bodies, and as the larger organisms consume them in turn, there is a greater toxic dose per gram ingested. As Man and his pet charges are  “Apex” predators we all end up with the stuff back in our bodies at a higher dose.  This is true for everything that is NOT food that is ingested and cannot get removed with the waste.  Food gets broken down by your digestive system or by your liver to its primary components: Carbon, Hydrogen, Oxygen, and Nitrogen plus some sulphur micro and macro minerals calcium, magnesium etc. Every cell gets washed in the serum that carries these molecules and each cell tries to figure out if it is food or foul—If you can’t  build cells or run enzymes with the molecules there, then the chemicals are either stored  in fat or liver–or put away in between muscle layers if it cannot be flushed out.  Its vitally important that you feed your  pet’s and your body daily with the building  blocks for your cells to regenerate and that you avoid putting bad stuff into the system.

Don’t be fooled! If a substance has “not yet been found” to cause cancer it might just mean that the correlation has not been documented in enough places- and that possibly too many doctors /research scientists are on the receiving end of a pay back! (Conspiracy theorist?  nah, its just business as usual! If  your research funding pays your mortgage who/what ya gunna call??) . You can  check pubmed entrez – the scientific research  site– for information about the anthropogenic (ie synthetic man made substances) found in the atmosphere that DO NOT BREAK DOWN in the ocean’s waters.  Type in any number of “food” preservatives and see what comes up.

As a rule of thumb: think

1) fluid therapy ensure food is hydrating (this *not * dry food)

2) avoid all “food” colourings (that are NOT food)  and most preservatives (vitamin E, C are ok)

3) Fresh is best.  The organic produce and pulp from your juicer is an awesome addition

4) add some green chlorophyll (spirulina, chlorella, kelp powder) – small amount for cat, larger for dogs.

5) seek help from an Integrative, Holistic Veterinarian.

ANIMAL WELLNESS ph 61 7 31221997
Veterinary Integrative Care Clinic AND Advanced Veterinary Dentistry
Greenslopes Shopping Mall
Shop 6B/700 Logan Road,
Greenslopes Qld 4120
www.animalwellness.com.au
http://www.facebook.com/?ref=home#!/animalwellness

https://naturopathvet.wordpress.com/

Dr Elaine Cebuliak BVSc MACVSc dentistry, Dip Ed, Dip Rem Massage, Cert Chinese Herbs, Cert IVAS Qual Acupuncture, CMAVA, Adv Dip Naturopathy, Adv Dip Herbal Med, Adv Dip Nutrition       ph 61-422413404
http://www.pethealth.com.au/Page/animal-massage-brisbane

Holistic = Homeopathy (only)??

Greetings Sentient ones!

I had an interesting weekend attending a surgery conference. On the whole it was most enjoyable, but it did raise my awareness that there is still an ignorance about what the term holistic entails. Holistic practitioners embrace a “heal the wholeness” of the individual.

There are many therapeutic models that are employed by the Naturopath, some would say this type of para-professional medical team member uses functional pathology, analysis of physical features and dietary/lifestyle/developmental history in a thorough way.

Often I am approached by clients and requested to “get to the bottom” of why they are experiencing different signs and symptoms. This means that I require a whole history and also review of their previous test results. (There is no point in spending extra dollars retesting eg. intestinal biopsies, recent blood work etc if they have recently been done!).

What I find fascinating is that some GP doctors or even specialists completely discredit the word “Holistic” as they simply have no idea about the meaning of the word. These doctors are simply confused about the terminology.
Although I have clients that tell me incredible stories about their, or their relatives healing at the hands of a Homeopathic practitioner, (ie this is a Homeopath- using a diluted water based therapy orally) many doctors assume that the word Holistic equals Homoeopathy=water=nothing in it (equates to quackery in their mind). They then further confuse the word Holistic with Naturopath and rudely disregard an entire profession of Natural healers!

I do wonder why these otherwise intelligent people (Doctors, Specialists) have no understanding of the functional pathology and mind-body medicine that Naturopaths practice. It seems that there is a separation of body parts in the minds of the standard western medical paradigm. That is the process by which emotions, and the hormones released by certain thinking processes (anxiety, worry, anger) leading to a cortisol stress response and physical body breakdown, is simply not recognised. Naturopaths like to delve down and get to the bottom of WHY this is happening, correcting the gut biome and changing diet, attitudes, and lifestyle while doing so.

It is for this reason that multiple supplements and lifestyle/nutritional changes are recommended. This may take several visits to the Naturopath while the client undergoes paradigm changes and baby steps forward. Its not too different to “going on a diet” and “getting more exercise” which is REALLY what the medical profession should be recommending anyway- instead of drug therapies!

In my Animal work I find that many of my veterinary patients reflect lifestyle concerns of the owner- that is the stresses of the home are also impinging on the health of their pet. Diet is also implicated as a factor, or cause of some of the dis-ease.

A Holistic practitioner recognises this, and although some Naturopaths also use Homoeopathy, most of us do all the above, and include diet recommendations, some form of body work, exercise, Herbal therapies and macro and micronutrient changes.

So please, inform your doctors and let them know that Naturopaths CAN and DO work with the medical profession as allied health care professionals. We ARE covered by most health care funds.

Go and drink some water now! 😉

What do I eat NOW?

I hear ya, you want 2014 to be the conquering year of getting in shape (round is a shape, right? ;-))
So here is a great kick start Joe Cross style (yes, grab that “Fat Sick and Nearly Dead” DVD http://www.fatsickandnearlydead.com/),
This means getting rid of sugar, carbs and increasing your nutrient value especially greens. Try this for breakfast and for a fast pick up during the day. Drink 6 glasses of mostly vege juices daily.

Green Smoothie Boost
Mix in high speed blender:
1 cup water (or coconut water)
1 stick celery
2 leaves kale
1 green apple
1/2 small cucumber (lebanese)
1 kiwifruit
50 gm baby spinach leaves
Juice of half lemon or lime
and organic spirulina, wheat grass, alfalfa, broccoli sprouts or phyto organic essential powder- 2 tsp.

Off you go! and have a GREAT day!

A variation to boost your detox and help your liver is to add 1-2 small pieces of turmeric. This is very helpful as an anti-inflammatory, antiarthritis, anticancer treatment. If you are detoxing for brain/neurological function (MS, Alzheimers etc) swallow 2 tablespoons of coconut oil twice a day as well.

If you have had many amalgam fillings it will take 1 month for every year you have had them to slowly detox your heavy metals out of your bones and fat deposits, your liver will need support while you do this to methylate the free radical toxins out (and into your poo! and out of your body) so you will need fibre daily. Try flax seed crackers- I love love love these ones from iherb.com http://www.iherb.com/search?sug=mary%27s+gone+crackers&kw=gone+crack&rank=2&x=0&y=0#p=1 and when you check out use my priority value code vet344 and you will receive 5-10$ off your first order! Its rewards based (not network marketing) so you will get your own code when you check out – share this and you too will gain rewards. Awesome way to shop for organics and yummy foods and supplements.

Naturopathic principles to support people with LHON Genetics

Naturopathic principles to support people with LHON Genetics
Since 1983 this Naturopath has been aware of a rare and devastating genetic disease that causes sudden irreversible blindness, with presently no treatment available and very little warning about its onset. You can read more about it here: http://www.ifond.org. and here:http://www.lhon.org/lhon/LHON.html You can read about the optic nerve here http://en.wikipedia.org/wiki/Optic_nerve
You see it was about this time that my brother, a fine and upstanding Dentist, found that he could not see the sutures he had placed the week before in his patient’s mouth. His optometrist advised him to take a break and rest his eyes from eye strain, as the optometrist could see no apparent cause to this sudden blindness while examining his retina. The ensuing months led to a bucket load of tests and hospitalisation in the London hospital for Nervous disorders, ruling out every possible brain disorder- Parasitic infection, heavy metal toxicity, MS, tumour, Parkinsons, Lou Gherigs, etc. All Nada. Negative. My bro was sent home back to Australia legally blind and unable to practice his life-long well studied career, with no obvious plan to move forward as there was no diagnosis. Hoping to regain his vision, and find a cause for this devastating disease was the focus of the next year. Unfortunately at that time there was no genetic testing, and many visits to multiple specialists were unfruitful. T he rule out factors added up and they came to the provisional diagnosis of LHON. No treatment, No CURE!
Causes: LHON is the acronym for Leber’s Hereditary Optic Neuropathy. It is a sudden blindness due to an inherited mitochondrial enzyme deficiency. There is some supportive evidence based data linking the onset to a TRIGGERED response caused by various Reactive Oxygen Species/Free Radicals . Free Radicals are by products of chemical reactions with the cell contributing to apoptosis or cells breaking down. Women can get LHON but the incidence is rarer, contributing to the theory that female hormones are somehow protective to the optic nerve.
Because there are triggering events in some cases- which lead to subsequent apoptosis of the optic nerve (=programmed cell death) it is possible that preventative steps may help.
This may also be true of many mitochondrial disease processes, and so it may be worthwhile considering possible treatment strategies that may help –especially in the early stages of the onset of blindness.
I will add a disclaimer here- it is not possible to diagnose or treat any disease via the internet, you will need to work out what is best in your own situation. What I will list below are some naturopathic principles that others- including myself– have found useful. You see a genetic test was produced in the early 90’s and I have found that all of my mitochondria and my kids are also affected. They are now in their late 20’s early 30’s. All are doing well, and are aware of their genetic potentials. Through the internet I have also found many individuals with my mutation –boys, girls, and several women- younger than I –HAVE also gone blind from this horrid disease. So far no other members of my family have been affected, except perhaps my mother who suffered from atrial fibrillation in the last 20 years of her life and eventually succumbed to a clotting stroke secondary to that. LHON also causes heart disease. Remember that mitochondria affect the WHOLE body, they are the power houses of your cells, the “eveready battery” system. It is for this reason that several LHON affected individuals have multiple health challenges. It is imperative that you seek your own pathway and visit your own GP and eye specialist to discuss these strategies. You may find some of these ideas and lifestyle hints helpful. However some herbal and orthomolecular vitamins and minerals maybe contraindicated with some medications. Speak with a medically trained herbalist and nutritionist and discuss with an integrative doctor.
AIM for a BALANCE of hormones and body function:
Specifically Insulin, Oestrogen, Progesterone, Thyroxine, and Cortisol.
“Normalising” the body’s various metabolic processes and keeping “good health” involves the disciplines of nutrition, exercise physiology, sleep cycles, Stress management, and environmental toxin awareness. Its all about what we EAT, THINK, and DO! Its Lifestyle factors: Food, Fun and Fitness. By maintaining a great diet high in plant phytochemical antioxidants, GOOD quality fat, staying well hydrated, with low levels of stress and a low/healthy BMI fat ratio, while avoiding various toxins (smoking—of all types, paint fumes, alcohol, chemical preservatives, artificial flavourings, dyes, insecticides, weedicides and drugs) you have a better chance of living WELL. This is the Naturopathic principle behind stabilising LHON mitochondria. Wild blood sugar fluctuations by eating inappropriate candy, lollies, sugar, cakes, pastry, pasta and bread are pro-inflammatory and cause insulin surges, which in turn affect adrenaline and cortisol levels. Eating a low GI (glucose index) diet with plenty of good fat, some protein and phytonutrients is key to health.
EMOTIONS:
The chemistry involved in the body is delicately balanced by hormones and food/nutrient intake. If you are releasing cortisol and adrenaline, the Calcium, Magnesium and other trace minerals are affected because every metabolic process in the body is affected! Yes even your kidneys will change their function if your brain puts out a signal that says STRESS!!! They will lose more vital nutrients to make way for other minerals to stay in the body to make more chemicals such as adrenaline and allow the blood pressure to elevate. Amazing systems our integrated organs! This is why families that are affected with a member who has/or is going blind need to acknowledge their grief and to seek counselling/meditation/or religious support to put back those “happy hormones” and return to a buzzing healthy body. Deal with it. For GOOD!
The grief and devastation to the individual and their family lasts a life- time with subsequent emotional roller coaster effects that continue to roll out over generations. Coping and living with dis-ease depends on the support structure of the family, the community, and the inherent strength of the individual. Find those groups, go to church, rotary or Lions club, or find a local community group with a similar interest (Chess or Golf—like my bro,line dancing, rock and roll, Agility dog handling, learning a new language, cooking etc).
Happy Hormones are linked to Happy emotions and will help balance your digestive system, your ability to absorb nutrients and will decrease your stress levels. Always a good thing. Seek your happiness bubble, as long as it is not self destructive! Exercise has been shown to increase happiness and decrease your risk of cancer by a whopping 37% so definitely add that to your Health achievement goal !

Research and lab rats:
Science takes at least 10-20 years to study medical phenomenon—the time PhD students work on and prepare their thesis and their Professors consider and work on the problem. To “do no harm” medically speaking scientific protocols and necessary ‘double blind placebo control” rules apply. Research grant proposals need to be garnered, and suppliers of cold hard cash need to be convinced that this research is necessary. This means that any preventative measures or possible treatments for a condition that does not affect a large percentage of the population is poorly funded and may even be stalled midway through its procedure. You can donate to this research via http://www.ifond.org.
While research is ongoing for LHON there have been only a few breakthroughs in the last 30 years that show promise. In the meantime hundreds more carriers have been identified throughout the world and many more souls have been inflicted by this optic nerve disease.
Through the gift of the internet and Facebook many LHON affected souls and their families have been able to communicate with each other, forming friendships across the globe which provid understanding and emotional support. It is through this avenue that I have been requested to write about my naturopathic understanding and personal experiences with LHON>
What has become apparent is that there is a resilience with many who have become blind, and who have gone on to develop a sense of humour about it and function well within society. Very few have regained a little vision over time, although most are still praying for a cure to restore their sight.

Let us break down some of the factors and possible triggers leading to the onset of LHON and for that matter any mitochondrial dis-ease.

Causes of Mitochondrial stress:
 Genetic (there are several areas on the mitochondrial DNA that are faulty-read about this in http://www.ifond.org)
 Obesity/Insulin Resistance / Inflammatory/dietary Metabolic reactions
 Infections
 Toxins
 Hormonal Imbalances – progesterone/oestradiol protective effects
 Stress
 Deficiencies of vitamins and other nutrients
 Exposure to environmental pollutants and radiation

Protective mechanisms for gene activity based on three main areas:
 Detoxification
 Methylation in the liver
Antioxidants

 Decrease in antioxidant status in the individual may contribute to DNA damage – increased free radical exposure without neutralisation
 As we age, the ability for the body to produce anti-oxidants declines dramatically
 Impairs the ability for damaged DNA to repair itself faster.
 Free radical damage to DNA from chemical changes alters the DNA structure and therefore gene expression
 Antioxidant status is imperative to be maintained especially as the body ages.
Important antioxidants:
 CoQ10
 Vitamin C
 Vitamin E
 Selenium
 Vitamin A
 B vitamins – especially B1,3,6,9,12 necessary for the liver to detoxify via the methylation cycle.

FOOD FACTORS:
It has been known for many years that what we eat (or don’t) is vital to how our body performs.
The role of Nutrition is key to physiological processes in the body– “the concept of health and dietary recommendations have been expanded to include achievement of genetic potential, prevention of disease and extension of longevity” Harper, AE, Am.J.clin.Nutr 1987 Vitamin and mineral deficiency at CRITICAL times are implicated in a number of pathological processes.
This is especially true in children, for instance if a child needs iron, vitamin A or iodine they NEED it NOW. Otherwise that child is going to pay for it for the rest of her life. If you meet that need the positive outcomes are glorious—2 Billion kids could be helped by supplementing these 3 things! (UNICEF. Micronutrient Initiative and United nations University).
If you have gut issues (see later blogs about gluten specifically) you may be harbouring inflammation, which releases damaging free radicals. Yep, those are the same nasty beasties that circulate through your body and bathe your optic nerve.
I hear you, you are asking: What do we need to eat?
Be aware that there is no ONE diet for everyone, as everyone has specific needs to stages of their life cycle. Growth, Pregnancy, new job, marathon running, lactating, and celiac disease all require different levels of nutrients, and specific co-factors.
There is, however ample scientific evidence to show that the advice on the Heart Tick foundation boxes of high sugar cereals is not correct. Today’s food pyramid is just WRONG—their emphasis at the bottom is on high processed sugar- refined in breads and pasta and this is fraught leading to inflammation. There is NO NEED to eat trans fats or processed margarine. Choose an unprocessed natural diet and avoid anything with numbers and preservatives. Do not eat empty calories- no sweets, cakes or candy/lollies. Avoid fried foods. Increase your omega 3 fatty acids, which should be fresh in foods such as chia, flax and other seeds and nuts and oily fish (Mackerel, salmon and a very little tuna- the latter has more mercury so should only be eaten no more than twice a month).
Nutritional imbalances are more common that frank single nutrient deficiencies in the western world. Beriberi (thiamine deficiency) Kwashiokor and Marasmus (overall protein deficiency) and Pellagra (vitamin B3 deficiency) is not common, however subclinical B6 and B12 deficiency could be underlying some neurological diseases.
The body is always changing and replacing cells. You are basically a new person every 7 years. Maybe that is why relationships suffer every 7 years. (Just kidding – no need to change partners every 7! They can change and grow with you too!).
The ability to switch on and switch off various metabolic processes using food therapy is called Nutrigenomics. We have found adding supplements and changing the diet to our chronic disease cases such as various dermatitides, cancer, arthritis, diabetes, and heart problems can greatly improve outcomes. Together with the necessary medical interventions this form of Integrative Medicine is superior to plain pharmaceutical measures.
Just a quick word about Diet: there are many different diets out there and many different types of body stages, ages and conditions. What suits one person may not suit another, and most doctors know bugger all about this! Nutritional colleges don’t even agree with each other, and certainly the RDI (Recommended Daily Intake), or RDA (Recommended daily allowance) vastly underestimates nutritional requirements for dis-ease treatments. It’s going to take some research to work out what your individual body needs, however be assured that good wholesome organic foods grown on health non toxic soil are bound to be better for you than toxic waste preservative- coal tar dyed processed crap loaded with sugar and insectide sprays.
I’m going to make this simple for you, if you follow this golden rule you will notice a huge health improvement:
Eat less CRAP:
C- carbonated drinks
R- REFINED SUGAR
A-artifical sweeteners & Colours
P- Processed foods
Diet and Nutrition are NOT the same thing. Diet refers to the foods that are consumed and chosen on a daily basis, and Nutrition is the the factors that are retained and utilised by the body. Therefore, as all good naturopaths will tell you, the state of your gut function and digestion and absorption are where you should concentrate your efforts for healthcare. See some later blogs about poo and you. Having a Bristol Stool chart comparison gives you some idea about where you need to aim your efforts. Basically on the scale of 1-6 where 1 is hard rabbit type of pellets (constipation) and 6 is diarrhoea- runny pats with no form, an ideal faecal movement is about a 4- a submarine affair with sausage like ends and about 4-5 links at least once a day. This is significant, as runny poos likely mean you are not absorbing your nutritient factors adequately and constipation means you are probably dehydrated and lacking magnesium and other elements necessary to tonify the bowel, as well as a sluggish bowel will harbour more toxicity and bad bacteria increasing inflammation in the body.
A quick way to improve your digestion is to drink 2 glasses of warm water with ½ a lemon squeezed into it first thing in the morning. Then go for a 10 minute walk or do some stretches. Disciplining yourself to do this has seen improvements in 90% of my patients. It’s a simple and achievable process- baby steps to better health! This will rehydrate you and alkalinise the body, as well as increasing the gastric enzymes and HCL required to start your digestion.
Body types and Mineral Metabolism:
Another aspect of balancing your metabolism is to pay attention to your body type, as the structure is often linked to trace mineral imbalances. Scientifically proven HTMA (Hair Tissue Mineral Analysis) may be performed- this will work out which minerals need adjusting, and help your body absorb the correct minerals. Visit a Naturopath to obtain a Naturopathic diagnosis, based on observation of your nails, tongue, diet recall, skin etc. If you cannot afford to do this, at least try the zinc test and examine your fingernails. If there are white marks on them you are likely zinc deficient, and this is a very important mineral cofactor for many metabolic processes in your body. The most common deficiencies are vitamin D3, Zinc, Selenium and omega 3 fatty acids. The most common excesses are processed foods and sugar. Fix these simple things and you will be on your way for health.
The two basic body types are the apple shape with more fat in the centre and above the middle core- this is also known as a sympathetic type. Sympathetic here refers to the autonomic nervous system and a sympathetic system is adrenaline driven, type A personality, likes or seeks stress and is present in about 30% of the western population. This is a more testosterone type, and although I have not seen any studies linking this body type to the incidence of LHON blindness, it may be possible to look at a data base and define this at some future date. There are more males falling into the sympathetic body type as well, and as more males become affected by LHON than females this might be a future research area to look at the composition of mineral balanced due to the neuro-endocrine function which determines body type. They have low levels of Calcium and Magnesium in hair and blood samples and may require these minerals to be supplemented.
The other main body type is called the parasympathetic body- it is more pear shaped and represents more than 60% of the western population (except in Scandinavia where there is an equal distribution across the board of the 2 body types!). Parasympathetic people are type B personalities and have higher levels of Calcium and phosphates in their blood and hair, are more sedentary and nurturing and less stress- seeking.
The corollary one must ask: What does the body need to make and protect myelin and optic nerve tissue?
First the body needs to be signalled and told what to do with the nutrition. This is related to hormone levels – hence this is why menopausal women are cautioned to use hormone replacement therapy to protect their capacity to make more mitochondria. Oestradiol gives the mitochondria a kick- and this is possibly why there is an increase in men going blind at around the 30 age mark. (Although to this author’s knowledge presently no one has actually done a study to measure these hormones and link them to the onselt of LHON disease in men).
Progesterone also supports myelin sheath cell makers. Wild Yam crème has been used effectively to help perimenopause and PMS women and may well help men with this genetic predisposition. The studies are yet to be done on this.
Nutritional care for the myelin: we need to feed those suckers- they are formed fromLipoproteins and B vitamins! Lipo-proteins are the structures making up cell membranes. YES: The body needs good quality fat for its cell structure. That is why the presently taught “food pyramid” which is bottom heavy on grains and flour is BAD for LHON people. Carbs are pro-inflammatory they burn quickly, do not add to structure, and cause an insulin surge followed by a dip, thereby creating a hunger for more- and linked to the present day obesity epidemic and increase in diabetes type 2. Dementia, a neurological disease is also called “Diabetes type 3” today for a good reason- a low fat high carbohydrate diet is linked to onset of dementia and Alzheimers disease. Good quality fat (butter, fish oil, flax oil) has an anti-inflammatory action and is useful for building cell structure.
There are many studies that show improvement of dementia patients if “good” fat (omega 3’s fish/flax oil and coconut oil) intake is increased with an antioxidant such as turmeric powder.
Similarly the naturopathic outcome of correcting a vitamin B12 or Fatty acid deficiency for nervous function has been well documented.
There are numerous other nutrients which act as antioxidants. These are phytochemicals found in foods, but the research from the Doheny eye institute supports the synthetic coenzyme Q 10 called Idebenone at somewhere between 300-600 mg/day.
Please be aware that if your doctor has prescribed statin drugs to lower your cholesterol you will be deficient in mitochondrial function and will need to at least supplement with coenzyme q 10 at a minimum of 300 mg twice a day. Statin drugs will decrease your ability to make vitamin D3 and a host of other hormones. They cause muscle weakness and mitochondrial deficiency. Idebenone may also be of benefit , and you may want to question your doctor carefully about the need to take these drugs and if nutritional functional foods may be of benefit, together with weight loss if you are obese.
Some functional foods include those high in antioxidants.
Antioxidants in foods include:
 Quercetin – in the skin of citrus, in pineapple core, red onions and other fruits.
 Resveratrol – in red grape skin
 Polyphenols , in many fruits, vegetables, herbs and teas
 Phytoestrogens- in clover, soya (use fermented, eg. Miso and tofu) cohosh, wild yam and sweet potatoes
A rule of thumb is if the fruit and vegetable are multicoloured (ie eat from the rainbow) you are likely to gain multiple antioxidants in your diet. Make a ton of vegetable juice fresh and eat a little fruit. Add fresh turmeric and ginger to your drinks. These will increase your ORAC scale. The higher the ORAC scale the more useful as a “free radical mopper” these drinks and foods are.
Detoxification:
This happens in the liver and free radicals and toxic substances are filtered out here (hence the requirement for no or low alcohol imbibation- and if you must choose red wine without sulphate preservatives, at least you will take in some resveratrol!) If you have a liver problem it will show up in blood tests as an elevation of ALKP and ALT.
It’s important to look after your liver. Take regular supplements of s-AME, Milk thistle, Vitamin E and Selenium, a multi B, Zinc and Sip Green tea often. Eat Artichoke and bitter herbs/lettuces (radicchio, rocket, Cap coy, Kang Kung, purslane, dandelion, spinach, parsley, Cilantro=Coriander) and collard greens regularly. Choose a mostly plant based diet and mostly organic (or wash/soak all fruit and vege in a detoxifying rinse- see www. naturopathvet.mysisel.com for organiclens)
If the liver is not cared for or abused (eg drinking alcohol- or drugs including antibiotics!) Problems with detoxification pathways will occur – this leads to DNA damage. DNA is sensitive to toxic chemicals – DNA expression and structure is altered with toxicity.
 Phase 1 – toxic metabolites are produced – need to be cleared effectively, otherwise accumulate – especially the steroid hormones.
Methylation:
Methyl groups – CH 3 – are utilised to regulate gene expression. (switches off/switches on where necessary). Therefore lack of methylation compromises this activity – gene expression is altered.
 Main nutrients for methylation processes:
o Folate, B6, B12, Methionine (1 methyl group), SAMe (3 methyl groups)
Inflammatory/neurotoxic factors:
 Higher BMI levels – more adipose tissue to store harmful steroid hormones derived from western diets – meats, poultry, eggs, dairy
 Xenoestrogens found in packaged foods, plastic containers, landfill, pesticides, fertilizers, agricultural soil, animals, fish, grains – mimic estrogen and are toxic – stored in fat tissue and contribute to carcinogenesis
Diet:
• Review your diet and consider the following:
– Food allergies/sensitivities – gluten is common and commonly missed/misunderstood. Some nuts (peanuts) sesame seeds, and milk proteins (casein) are next in line.
– Organic foods – reducing the processed and artificial components of the diet as much as possible
– Alkalinising the diet – reducing acid-forming foods if necessary cut out red meat and sugar.
– Increase anti-inflammatory foods – oily fish, onions, garlic, citrus, tumeric, leafy greens, celery, berries
– Reduce heated saturated fats, trans and hydrogenated fats – use monounsaturated fats for cooking and in salads – olive and avocado or coconut oil.
– Reduce refined sugars and carbohydrates – these are pro inflammatory
– Reduce red meat intake – inflammatory
– Increase fibre – improves excretion
– Increase sulfur foods (cruciferous veges broccoli, brussel sprouts) – liver detox
– Reduce the burden on digestion – easier to digest foods – nutritionally dense foods – eat more pumpkin, chicken soup, slow cooked stews, eggs.
– Introduce chlorophyll into the diet via juicing – increasing green leafy veg. – helps with detox and as a blood cleanser
– Maintain healthy protein intake – quality protein foods – yoghurt, eggs, salmon, nuts.
– Maintain healthy calorie intake – to avoid weight loss
– Herbal teas – ginger, rosehip, peppermint, withania, passionflower, GREEN TEA
Increase the intake of certain Phytochemicals found in plants which have undergone research are as follows:
• Genistein
– an Isoflavone found in Soy and Flaxseed – inhibits angiogenesis
– may play a major role in the prevention of breast and testicular cancers
– antioestrogenic
– mimic estrogen – attaches to same receptors
– inhibits 5-alpha reductase in prostate (Davis, SR.et.al, 1999)
– anti-tumour effects
– Curcumin
– obtained from Tumeric
– inhibit breast cancer development
curcumin and genistein – most potent inhibitors against growth of human breast tumour cells induced by pesticides
Lignans
• Insoluble fibres found in flaxseed, bran, lentils, garlic, celery, outer husks of grains
– bind to oestrogen, testosterone and DHT to increase excretion and prevent accumulation
– Flaxseed contains the highest amount of lignans (Schultz, TD et.al, 1991) Chia seeds are also helpful
– Contribute as a food source for gut bacteria to improve immunity and resistance to disease. Globe artichoke , chicory and melons are also a great source of inulin acting as a prebiotic for “good gut bugs to grow”. Good guts create a biome which manufactures helpful hormones and vitamin K and B’s. These assist in brain function, and well your optic nerve is part of your brain!
– Anti-tumour, Anti-mitotic, Anti-oxidant, oestrogen regulating effect via receptor binding
• Green Tea
– contains the polyphenol Epigallocatechin-3-Gallate (EGCG)
– anti-angiogenic, anti-inflammatory, induces apoptosis of human epidermoid carcinoma cells and regulates cell cycles
– preventative against a variety of cancer types especially skin cancers
Lycopene
– carotenoid family – found in red flesh fruits and vegetables
– highest in tomatoes – also in red capsicums, goji berries, pawpaw, carrots
– Inhibits growth promoting effects of cancer cells
– Activates tumour suppressor genes
– Indole-3-carbinol
– Found in cruciferous vegetables
– Inhibits formation of carcinogenic eostrogens – 16-HydroxyEstrone
– Prevents estrogen-dependent cancers, prevents cervical cancer from HPV (Cancer Research 59, 3991-3997, 1999)
– Enhances chemotherapy effects
– Induces detoxification pathways
– Rosemary
– Carnosol – chemical in Rosemary found to be:
– Effective against blocking tumorgenesis in human bronchial epithelial cells (Offord, EA et.al 1995)
– Reverses resistence to chemotherapy drug treatment
Fish Oils
• Quercetin
– Found in red onions, berries, apples, beetroot, citrus
– Anti-oxidant
– Inhibits drug resistant estrogen receptor treatments
Potentiates
Detoxification for various organs:
– Liver support – Sulfur amino acids – Methionine, Taurine, Glutathione, Cysteine
– A, quercetinCo-factors for enzymes – Selenium, Magnesium, B group, Vitamin C, CoQ10, Manganese, Copper, Vitamin E
– Gut Support – soluble and insoluble fibre, pre and probiotics, vitamin A, Zinc, slippery elm
– Kidney Support – All antioxidants, Vitamin C, Selenium etc. Herbs – celery, Rhemannia and other Diuretic herbs
– Lung support – broccoli, glutathione, vitamin
– Heart Health- Hawthorne berry, Selenium, Vitamin E

PHEW! That’s a lot to take in if you are new to this game of nutritional science, right?
So to go with my baby steps plan this is an easy suggestion. Buy a juicer. Listen and watch Joe Cross’s movie “Fat, Sick and Nearly Dead” and drink a juice with pineapple, carrot, beetroot, celery, turmeric and ginger daily for a week then mix up your green juices so that you are drinking fresh 3 times a week minimum. If you are having signs of blindness IMMEDIATELY jump on the juices and add more good fat (butter, coconut oil, fish oil, flax oil) to your diet and remove sugars and processed foods. Eat goji berries like they are going out of style- by the handfuls. Take your Idebenone at HIGH doses immediately, and some vitamin E. Have your vit D3 checked and see a naturopath to have your minerals analysed.
So you are probably asking how am I going? So far I have not gone blind. When we first learned about LHON it was thought to only affect males, generally at the 30 year stage. I have since found many women, girls and young boys have been struck with this blindness at all ages. Perhaps I have managed myself well, or perhaps my hormones have protected me. This is what I have found with my own body, and remember everyone is different- even if we have the same genetic mitochondrial enzyme deficiency. My particular DNA pattern is 11778- it has a poor prognosis for vision return if affected and is implicated in many LHON plus signs.
My heart is OK, with a mild murmur which is thought to be no problem at this stage, however my mother suffered from Atrial fibrillation for many years prior to her serious stroke, so I am cognisant that I must be vigilant and will take warfarin if my heart becomes a fibrillation candidate. Fortunately my other parameters seem stable and healthy.
My vitamin D3 levels were down, and everyone should have these checked as this influences all your metabolic processes. In order to make D3 you need GOOD cholesterol in your diet, and sunshine. If either are lacking you may need to supplement orally, and the dose is often a lot higher than is on the lable. I take massive doses if ever I have a sign of a cold or a flu, but only for a day or 2- like 100,000 international units. I also increase vitamin C in the bioflavonoid range and zinc. I am almost never sick.
As a desk nerd and Naturopath I have noticed signs of pre syndrome x (cortisol undoubtedly playing a part as my weight gain coincided with the stress of looking after my stroked out mother) which led to a plunge in my thyroid.
Since Mother’s passing, I am addressing this now with increasing my walking and beach visits, and adding more kelp to my diet (sushi! Yum). Also removing gluten has been a big help – which causes leaky gut and is inflammatory.
I am a 56 year old menopausal woman who has worked and studied most of my life. So far I have had what I consider 2 near miss incidences of blindness in my left eye. Both times vision has recovered immediately after taking mega doses of antioxidants. These are what I have taken:
Synthetic Idebenone (900 mg /day for a few days only when the eye went blurry- I don’t take it every day) a goji berry drink with high ORAC levels from Young Living Essential Oils called Ningxia Red, several cups of strong green tea, a Cathay chinese herb called Ming mu di huang wan, and I chewed them all down with handfuls of dried Goji berries. I also make berry smoothies once a fortnight out of mixed frozen berries (YUM!) with a blender, and take Entrapro.com probiotics occasionally. I love Turmeric and curried food and eat this almost daily, often with coconut oil. I have at various times taken Neways supplements including Revenol, and also Usana antioxidants. These are all good, but I feel the greatest “hit” has been from coconut oil and turmeric plus the Goji drink. The natural progesterone effect of the wild yam crème has also been helpful to normalise hot flashes, although the chinese formula Liu wei di huang wan (also called Rehmannia 6) has been more useful.
I have also noticed that the Blackmore’s celloid of PS (potassium sulphate) is very helpful for my energy levels and I will chew one of those when feeling tired or stressed. It is very safe and can be taken several times a day as it is such a low dose. Possibly ingesting bananas may help, as a good source of potassium. I just had a banana smoothie while writing this blog, in fact.
Recently I have been taking a bioidentical hormone with a small amount of progesterone sublingually as I noticed when I was back from a teaching mission (about diabetes prevention) in Bali that I was having small sweats- thank goodness it is NOT malaria! I had this PCR tested for! I may still have some residual infection in some root canal work I have recently had performed- but THAT is a whole new blog. Dentistry is my “pet” special field, and I have written books on it! My mouth has been an adventure in dentition since I was quite young and was dealt a monobrow short sighted overenthusiastic amalgam filling overdrilling dentist. I have been “dealing with it” ever since.
Another thing: life is not immortal, and we are best to take a philosophical stance with the cards we are dealt with.
“The Pessimist complains about the wind,
The Optimist expects it to change’
And the REALIST adjusts the sail”
William A Ward.

Adjust your sails, fix your own boat- because you are the captain of your own ship. No one else controls you but YOU!
Best in health for now-
Cheers all,
And keep your mitochondria mumbling along………… stay healthy, be wise and be gentle on your body, it’s there for LIFE!